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  5. PBANKA_1340100

PBANKA_1340100 (LDH)


Aliases : LDH

Description : SSF51735: NAD(P)-binding domain superfamily, SSF56327: Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal. Pfam domain(s): PF02866: lactate/malate dehydrogenase, alpha/beta C-terminal domain, PF00056: lactate/malate dehydrogenase, NAD binding domain.


Gene families : OG_01_0000387 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000387_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pbe RNA-seq: PBANKA_1340100
Cluster P. berghei: Cluster_36

Target Alias Description ECC score Gene Family Method Actions
PF3D7_1324900 LDH SSF51735: NAD(P)-binding domain superfamily, SSF56327:... 0.2 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA PlasmoDB
CC GO:0005622 intracellular ISO PlasmoDB
BP GO:0005975 carbohydrate metabolic process IEA PlasmoDB
MF GO:0016491 oxidoreductase activity IEA Interproscan predictions
MF GO:0016491 oxidoreductase activity IEA PlasmoDB
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA Interproscan predictions
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA PlasmoDB
BP GO:0019752 carboxylic acid metabolic process IEA PlasmoDB
BP GO:0055114 oxidation-reduction process IEA Interproscan predictions
BP GO:0055114 oxidation-reduction process IEA PlasmoDB
Toggle parental
Type GO Term Name Evidence Source
CC GO:0000015 phosphopyruvate hydratase complex IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0000287 magnesium ion binding IEP Predicted GO
CC GO:0000323 lytic vacuole IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
BP GO:0000723 telomere maintenance IEP Predicted GO
MF GO:0000900 translation repressor activity, mRNA regulatory element binding IEP Predicted GO
BP GO:0001731 formation of translation preinitiation complex IEP Predicted GO
BP GO:0001817 regulation of cytokine production IEP Predicted GO
BP GO:0001818 negative regulation of cytokine production IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
BP GO:0002181 cytoplasmic translation IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003697 single-stranded DNA binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003924 GTPase activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0004416 hydroxyacylglutathione hydrolase activity IEP Predicted GO
MF GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEP Predicted GO
MF GO:0004516 nicotinate phosphoribosyltransferase activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004634 phosphopyruvate hydratase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004807 triose-phosphate isomerase activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005737 cytoplasm IEP Predicted GO
CC GO:0005764 lysosome IEP Predicted GO
CC GO:0005767 secondary lysosome IEP Predicted GO
CC GO:0005773 vacuole IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005850 eukaryotic translation initiation factor 2 complex IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
CC GO:0005856 cytoskeleton IEP Predicted GO
BP GO:0006089 lactate metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006091 generation of precursor metabolites and energy IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006109 regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006417 regulation of translation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006754 ATP biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
CC GO:0008250 oligosaccharyltransferase complex IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009145 purine nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009206 purine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009435 NAD biosynthetic process IEP Predicted GO
BP GO:0009438 methylglyoxal metabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0010322 regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010323 negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010563 negative regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0010565 regulation of cellular ketone metabolic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010608 posttranscriptional regulation of gene expression IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
BP GO:0010675 regulation of cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0010677 negative regulation of cellular carbohydrate metabolic process IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016790 thiolester hydrolase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
MF GO:0019203 carbohydrate phosphatase activity IEP Predicted GO
BP GO:0019216 regulation of lipid metabolic process IEP Predicted GO
BP GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEP Predicted GO
BP GO:0019357 nicotinate nucleotide biosynthetic process IEP Predicted GO
BP GO:0019358 nicotinate nucleotide salvage IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019365 pyridine nucleotide salvage IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019747 regulation of isoprenoid metabolic process IEP Predicted GO
MF GO:0019843 rRNA binding IEP Predicted GO
CC GO:0020020 food vacuole IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
CC GO:0030139 endocytic vesicle IEP Predicted GO
MF GO:0030145 manganese ion binding IEP Predicted GO
MF GO:0030371 translation repressor activity IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031410 cytoplasmic vesicle IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
CC GO:0032010 phagolysosome IEP Predicted GO
BP GO:0032200 telomere organization IEP Predicted GO
BP GO:0032268 regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0032675 regulation of interleukin-6 production IEP Predicted GO
BP GO:0032715 negative regulation of interleukin-6 production IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0034248 regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042026 protein refolding IEP Predicted GO
BP GO:0042182 ketone catabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
MF GO:0043047 single-stranded telomeric DNA binding IEP Predicted GO
BP GO:0043094 cellular metabolic compound salvage IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043173 nucleotide salvage IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043244 regulation of protein complex disassembly IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
BP GO:0044283 small molecule biosynthetic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
MF GO:0045182 translation regulator activity IEP Predicted GO
CC GO:0045335 phagocytic vesicle IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045827 negative regulation of isoprenoid metabolic process IEP Predicted GO
BP GO:0045833 negative regulation of lipid metabolic process IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0045912 negative regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0045936 negative regulation of phosphate metabolic process IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046034 ATP metabolic process IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046185 aldehyde catabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0046434 organophosphate catabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046497 nicotinate nucleotide metabolic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046890 regulation of lipid biosynthetic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0047429 nucleoside-triphosphate diphosphatase activity IEP Predicted GO
BP GO:0048519 negative regulation of biological process IEP Predicted GO
MF GO:0050308 sugar-phosphatase activity IEP Predicted GO
BP GO:0051055 negative regulation of lipid biosynthetic process IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051239 regulation of multicellular organismal process IEP Predicted GO
BP GO:0051241 negative regulation of multicellular organismal process IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0051596 methylglyoxal catabolic process IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
BP GO:0060249 anatomical structure homeostasis IEP Predicted GO
BP GO:0061727 methylglyoxal catabolic process to lactate IEP Predicted GO
BP GO:0062012 regulation of small molecule metabolic process IEP Predicted GO
BP GO:0062014 negative regulation of small molecule metabolic process IEP Predicted GO
BP GO:0071071 regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071072 negative regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072523 purine-containing compound catabolic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
MF GO:0090079 translation regulator activity, nucleic acid binding IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0097708 intracellular vesicle IEP Predicted GO
MF GO:0098847 sequence-specific single stranded DNA binding IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
BP GO:1903725 regulation of phospholipid metabolic process IEP Predicted GO
BP GO:1903726 negative regulation of phospholipid metabolic process IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR022383 Lactate/malate_DH_C 153 308
IPR001236 Lactate/malate_DH_N 6 149
PlasmoDB LDH
PlasmoDB PB000185.00.0
PlasmoDB PBANKA_134010