PBANKA_1358600 (IDH)

Aliases : IDH

Description : SSF53659: 20-02-2019. Pfam domain(s): PF00180: Isocitrate/isopropylmalate dehydrogenase.

Gene families : OG_01_0000395 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000395_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1358600
Cluster	P. berghei: Cluster_46

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1345700	IDH	SSF53659: No description available. Pfam domain(s):...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000287	magnesium ion binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004448	isocitrate dehydrogenase activity	None	Extended
MF	GO:0004450	isocitrate dehydrogenase (NADP+) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	ISO	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006099	tricarboxylic acid cycle	ISO	PlasmoDB
BP	GO:0006101	citrate metabolic process	None	Extended
BP	GO:0006102	isocitrate metabolic process	IEA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	Interproscan predictions
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA	PlasmoDB
BP	GO:0016999	antibiotic metabolic process	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	IEA	PlasmoDB
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072350	tricarboxylic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000932	P-body	IEP	Predicted GO
MF	GO:0004139	deoxyribose-phosphate aldolase activity	IEP	Predicted GO
MF	GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	IEP	Predicted GO
MF	GO:0004352	glutamate dehydrogenase (NAD+) activity	IEP	Predicted GO
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004725	protein tyrosine phosphatase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005216	ion channel activity	IEP	Predicted GO
MF	GO:0005261	cation channel activity	IEP	Predicted GO
MF	GO:0005262	calcium channel activity	IEP	Predicted GO
MF	GO:0005381	iron ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005385	zinc ion transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005768	endosome	IEP	Predicted GO
CC	GO:0005787	signal peptidase complex	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006103	2-oxoglutarate metabolic process	IEP	Predicted GO
BP	GO:0006106	fumarate metabolic process	IEP	Predicted GO
BP	GO:0006119	oxidative phosphorylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006536	glutamate metabolic process	IEP	Predicted GO
BP	GO:0006538	glutamate catabolic process	IEP	Predicted GO
BP	GO:0006627	protein processing involved in protein targeting to mitochondrion	IEP	Predicted GO
BP	GO:0006662	glycerol ether metabolic process	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
BP	GO:0006783	heme biosynthetic process	IEP	Predicted GO
BP	GO:0006784	heme a biosynthetic process	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006874	cellular calcium ion homeostasis	IEP	Predicted GO
BP	GO:0006875	cellular metal ion homeostasis	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
CC	GO:0008541	proteasome regulatory particle, lid subcomplex	IEP	Predicted GO
BP	GO:0009063	cellular amino acid catabolic process	IEP	Predicted GO
BP	GO:0009065	glutamine family amino acid catabolic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009264	deoxyribonucleotide catabolic process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015085	calcium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
BP	GO:0016054	organic acid catabolic process	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016417	S-acyltransferase activity	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
BP	GO:0016485	protein processing	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Predicted GO
MF	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016748	succinyltransferase activity	IEP	Predicted GO
MF	GO:0016751	S-succinyltransferase activity	IEP	Predicted GO
MF	GO:0016832	aldehyde-lyase activity	IEP	Predicted GO
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
CC	GO:0017087	mitochondrial processing peptidase complex	IEP	Predicted GO
BP	GO:0018904	ether metabolic process	IEP	Predicted GO
BP	GO:0019551	glutamate catabolic process to 2-oxoglutarate	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
MF	GO:0022838	substrate-specific channel activity	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0030904	retromer complex	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	IEP	Predicted GO
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	IEP	Predicted GO
BP	GO:0034982	mitochondrial protein processing	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0043649	dicarboxylic acid catabolic process	IEP	Predicted GO
BP	GO:0044282	small molecule catabolic process	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044432	endoplasmic reticulum part	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	IEP	Predicted GO
CC	GO:0045252	oxoglutarate dehydrogenase complex	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046148	pigment biosynthetic process	IEP	Predicted GO
BP	GO:0046160	heme a metabolic process	IEP	Predicted GO
BP	GO:0046395	carboxylic acid catabolic process	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0051604	protein maturation	IEP	Predicted GO
MF	GO:0051920	peroxiredoxin activity	IEP	Predicted GO
BP	GO:0055074	calcium ion homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0071344	diphosphate metabolic process	IEP	Predicted GO
BP	GO:0072503	cellular divalent inorganic cation homeostasis	IEP	Predicted GO
BP	GO:0072507	divalent inorganic cation homeostasis	IEP	Predicted GO
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR024084	IsoPropMal-DH-like_dom	35	430

External Links

PlasmoDB	PB000917.03.0
PlasmoDB	PBANKA_135860

PBANKA_1358600 (IDH)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation