PBANKA_1360000 (TOP3)

Aliases : TOP3

Description : SSF56712: DNA topoisomerase, type IA, core domain. Pfam domain(s): PF01751: Toprim domain, PF01131: DNA topoisomerase.

Gene families : OG_01_0000397 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000397_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1360000
Cluster	P. berghei: Cluster_28

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan predictions
MF	GO:0003916	DNA topoisomerase activity	IEA	PlasmoDB
MF	GO:0003917	DNA topoisomerase type I activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan predictions
BP	GO:0006265	DNA topological change	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000994	RNA polymerase III core binding	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006359	regulation of transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009892	negative regulation of metabolic process	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Predicted GO
BP	GO:0010629	negative regulation of gene expression	IEP	Predicted GO
BP	GO:0016480	negative regulation of transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
MF	GO:0043175	RNA polymerase core enzyme binding	IEP	Predicted GO
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
BP	GO:0048523	negative regulation of cellular process	IEP	Predicted GO
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Predicted GO
MF	GO:0070063	RNA polymerase binding	IEP	Predicted GO
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	7	150
IPR013497	Topo_IA_cen	166	639

External Links

PlasmoDB	PB000147.00.0
PlasmoDB	PB301170.00.0
PlasmoDB	PBANKA_136000

PBANKA_1360000 (TOP3)

Expression Profile

Co-expression Networks

Functional Annotation