PBANKA_1416900 (SMC2)

Aliases : SMC2

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase, SSF57997: 20-02-2019, SSF75553: SMCs flexible hinge superfamily. Pfam domain(s): PF02463: RecF/RecN/SMC N terminal domain, PF06470: SMC proteins Flexible Hinge Domain.

Gene families : OG_01_0002071 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002071_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1416900
Cluster	P. berghei: Cluster_29

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1318400	SMC2	SSF57997: No description available, SSF75553: SMCs...	0.16	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan predictions
CC	GO:0005694	chromosome	IEA	PlasmoDB
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051276	chromosome organization	IEA	Interproscan predictions
BP	GO:0051276	chromosome organization	IEA	PlasmoDB
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
MF	GO:0003677	DNA binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003916	DNA topoisomerase activity	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0005310	dicarboxylic acid transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005658	alpha DNA polymerase:primase complex	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006259	DNA metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006265	DNA topological change	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0007051	spindle organization	IEP	Predicted GO
BP	GO:0007052	mitotic spindle organization	IEP	Predicted GO
MF	GO:0008517	folic acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
MF	GO:0042887	amide transmembrane transporter activity	IEP	Predicted GO
BP	GO:0043086	negative regulation of catalytic activity	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0044092	negative regulation of molecular function	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
BP	GO:0051095	regulation of helicase activity	IEP	Predicted GO
BP	GO:0051097	negative regulation of helicase activity	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051225	spindle assembly	IEP	Predicted GO
BP	GO:0051336	regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
BP	GO:0070925	organelle assembly	IEP	Predicted GO
BP	GO:0071897	DNA biosynthetic process	IEP	Predicted GO
MF	GO:0072349	modified amino acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0090307	mitotic spindle assembly	IEP	Predicted GO
MF	GO:0090482	vitamin transmembrane transporter activity	IEP	Predicted GO
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905774	regulation of DNA helicase activity	IEP	Predicted GO
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Predicted GO
BP	GO:2001251	negative regulation of chromosome organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003395	RecF/RecN/SMC_N	2	1186
IPR010935	SMC_hinge	533	663

External Links

PlasmoDB	PB000269.01.0
PlasmoDB	PB001653.02.0
PlasmoDB	PB301085.00.0
PlasmoDB	PB301511.00.0
PlasmoDB	PBANKA_141690

PBANKA_1416900 (SMC2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation