PBANKA_1426500 (CUL1)

Aliases : CUL1

Description : SSF75632: Cullin homology domain superfamily, SSF46785: Winged helix DNA-binding domain superfamily, SSF74788: Cullin repeat-like-containing domain superfamily. Pfam domain(s): PF00888: Cullin family, PF10557: Cullin protein neddylation domain.

Gene families : OG_01_0000412 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000412_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1426500
Cluster	P. berghei: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_0811000	CUL1	SSF74788: Cullin repeat-like-containing domain...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	Interproscan predictions
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010498	proteasomal protein catabolic process	None	Extended
CC	GO:0019005	SCF ubiquitin ligase complex	ISS	PlasmoDB
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0030163	protein catabolic process	None	Extended
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
CC	GO:0031461	cullin-RING ubiquitin ligase complex	None	Extended
MF	GO:0031625	ubiquitin protein ligase binding	IEA	Interproscan predictions
MF	GO:0031625	ubiquitin protein ligase binding	IEA	PlasmoDB
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
MF	GO:0044389	ubiquitin-like protein ligase binding	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
CC	GO:1990234	transferase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000139	Golgi membrane	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
BP	GO:0001932	regulation of protein phosphorylation	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0004333	fumarate hydratase activity	IEP	Predicted GO
MF	GO:0004652	polynucleotide adenylyltransferase activity	IEP	Predicted GO
MF	GO:0004768	stearoyl-CoA 9-desaturase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005310	dicarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005326	neurotransmitter transporter activity	IEP	Predicted GO
MF	GO:0005328	neurotransmitter:sodium symporter activity	IEP	Predicted GO
CC	GO:0005783	endoplasmic reticulum	IEP	Predicted GO
CC	GO:0005886	plasma membrane	IEP	Predicted GO
CC	GO:0005952	cAMP-dependent protein kinase complex	IEP	Predicted GO
BP	GO:0006106	fumarate metabolic process	IEP	Predicted GO
BP	GO:0006260	DNA replication	IEP	Predicted GO
BP	GO:0006536	glutamate metabolic process	IEP	Predicted GO
BP	GO:0006537	glutamate biosynthetic process	IEP	Predicted GO
BP	GO:0006836	neurotransmitter transport	IEP	Predicted GO
MF	GO:0008517	folic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008603	cAMP-dependent protein kinase regulator activity	IEP	Predicted GO
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015095	magnesium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015293	symporter activity	IEP	Predicted GO
MF	GO:0015294	solute:cation symporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015370	solute:sodium symporter activity	IEP	Predicted GO
BP	GO:0015693	magnesium ion transport	IEP	Predicted GO
MF	GO:0015930	glutamate synthase activity	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016040	glutamate synthase (NADH) activity	IEP	Predicted GO
BP	GO:0016197	endosomal transport	IEP	Predicted GO
MF	GO:0016215	acyl-CoA desaturase activity	IEP	Predicted GO
BP	GO:0016482	cytosolic transport	IEP	Predicted GO
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Predicted GO
MF	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Predicted GO
MF	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030904	retromer complex	IEP	Predicted GO
CC	GO:0030906	retromer, cargo-selective complex	IEP	Predicted GO
BP	GO:0031123	RNA 3'-end processing	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
BP	GO:0042147	retrograde transport, endosome to Golgi	IEP	Predicted GO
BP	GO:0042325	regulation of phosphorylation	IEP	Predicted GO
BP	GO:0043631	RNA polyadenylation	IEP	Predicted GO
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
MF	GO:0045181	glutamate synthase activity, NAD(P)H as acceptor	IEP	Predicted GO
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0070566	adenylyltransferase activity	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
MF	GO:0072349	modified amino acid transmembrane transporter activity	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
MF	GO:0090482	vitamin transmembrane transporter activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001373	Cullin_N	26	750
IPR019559	Cullin_neddylation_domain	776	836

External Links

PlasmoDB	PB001422.02.0
PlasmoDB	PB301491.00.0
PlasmoDB	PBANKA_142650

PBANKA_1426500 (CUL1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation