PBANKA_1440700 (UBA1)

Aliases : UBA1

Description : SSF69572: Ubiquitin-activating enzyme. Pfam domain(s): PF09358: Ubiquitin fold domain, PF00899: ThiF family, PF16190: Ubiquitin-activating enzyme E1 FCCH domain, PF10585: Ubiquitin-activating enzyme active site, PF16191: Ubiquitin-activating enzyme E1 four-helix bundle.

Gene families : OG_01_0002166 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002166_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1440700
Cluster	P. berghei: Cluster_40

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1225800	UBA1	SSF69572: Ubiquitin-activating enzyme. Pfam domain(s):...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004839	ubiquitin activating enzyme activity	ISO	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	ISO	PlasmoDB
BP	GO:0006464	cellular protein modification process	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEA	Interproscan predictions
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain	IEP	Predicted GO
CC	GO:0000502	proteasome complex	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003729	mRNA binding	IEP	Predicted GO
MF	GO:0003923	GPI-anchor transamidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004345	glucose-6-phosphate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity	IEP	Predicted GO
MF	GO:0004512	inositol-3-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004824	lysine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004830	tryptophan-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005087	Ran guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005672	transcription factor TFIIA complex	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0005975	carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006020	inositol metabolic process	IEP	Predicted GO
BP	GO:0006021	inositol biosynthetic process	IEP	Predicted GO
BP	GO:0006098	pentose-phosphate shunt	IEP	Predicted GO
BP	GO:0006430	lysyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006436	tryptophanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006498	N-terminal protein lipidation	IEP	Predicted GO
BP	GO:0006499	N-terminal protein myristoylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006606	protein import into nucleus	IEP	Predicted GO
BP	GO:0006739	NADP metabolic process	IEP	Predicted GO
BP	GO:0006771	riboflavin metabolic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008374	O-acyltransferase activity	IEP	Predicted GO
MF	GO:0008531	riboflavin kinase activity	IEP	Predicted GO
CC	GO:0008537	proteasome activator complex	IEP	Predicted GO
BP	GO:0009231	riboflavin biosynthetic process	IEP	Predicted GO
MF	GO:0010181	FMN binding	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0015959	diadenosine polyphosphate metabolic process	IEP	Predicted GO
BP	GO:0015960	diadenosine polyphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0015965	diadenosine tetraphosphate metabolic process	IEP	Predicted GO
BP	GO:0015966	diadenosine tetraphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0016051	carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
BP	GO:0016255	attachment of GPI anchor to protein	IEP	Predicted GO
MF	GO:0016872	intramolecular lyase activity	IEP	Predicted GO
BP	GO:0017038	protein import	IEP	Predicted GO
MF	GO:0017057	6-phosphogluconolactonase activity	IEP	Predicted GO
BP	GO:0018377	protein myristoylation	IEP	Predicted GO
MF	GO:0019107	myristoyltransferase activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030119	AP-type membrane coat adaptor complex	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030126	COPI vesicle coat	IEP	Predicted GO
CC	GO:0030131	clathrin adaptor complex	IEP	Predicted GO
MF	GO:0030276	clathrin binding	IEP	Predicted GO
BP	GO:0031365	N-terminal protein amino acid modification	IEP	Predicted GO
MF	GO:0032266	phosphatidylinositol-3-phosphate binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0033365	protein localization to organelle	IEP	Predicted GO
BP	GO:0034504	protein localization to nucleus	IEP	Predicted GO
BP	GO:0034613	cellular protein localization	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0042176	regulation of protein catabolic process	IEP	Predicted GO
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Predicted GO
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0042765	GPI-anchor transamidase complex	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044161	host cell cytoplasmic vesicle	IEP	Predicted GO
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044431	Golgi apparatus part	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
CC	GO:0044437	vacuolar part	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048193	Golgi vesicle transport	IEP	Predicted GO
BP	GO:0051156	glucose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051170	import into nucleus	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
MF	GO:0061608	nuclear import signal receptor activity	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
BP	GO:0070727	cellular macromolecule localization	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0072594	establishment of protein localization to organelle	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
MF	GO:0140104	molecular carrier activity	IEP	Predicted GO
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Predicted GO
CC	GO:1905368	peptidase complex	IEP	Predicted GO
CC	GO:1905369	endopeptidase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000594	ThiF_NAD_FAD-bd	46	470
IPR018965	Ub-activating_enz_E1_C	1023	1115
IPR032420	E1_4HB	296	397
IPR000594	ThiF_NAD_FAD-bd	487	983
IPR032418	E1_FCCH	226	292
IPR019572	UBA_E1_Cys	671	921

External Links

PlasmoDB	PB000204.03.0
PlasmoDB	PBANKA_144070

PBANKA_1440700 (UBA1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation