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Heatmap: Cluster_43 (P. berghei)

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Gene
Asexual: SRP099925
Asexual, PbSR-MG KO: SRP109709
10 hpi, ab libitum: SRP059210
10 hpi, diet restriction: SRP059210
10 hpi, ab libitum, kin KO: SRP059210
10 hpi, diet restriction, kin KO: SRP059210
16 hpi, WT: ERP004868
16 hpi, CL: ERP004868
Trophozoite, 16 hpi: SRP027529
Schizont, predicted: ERP021229
Schizont, WT: SRP073801
Schizont, 22 hpi: SRP027529
Schizont: ERP004598
Schizont, ap2-g KO: SRP073801
Schizont, ap2-g2 KO: SRP073801
Schizont, ap2-l KO: SRP073801
Schizont, ap2-o KO: SRP073801
Schizont, ap2-o2 KO: SRP073801
Schizont, ap2-o3 KO: SRP073801
Schizont, ap2-o4 KO: SRP073801
Schizont, ap2-sp KO: SRP073801
Schizont, ap2-sp2 KO: SRP073801
Schizont, ap2-sp3 KO: SRP073801
Schizont, PBANKA_131970 KO: SRP073801
Schizont, ppm2 KO: ERP004598
Schizont, ppm5 KO: ERP004598
Gametocyte, WT: SRP073801
Gametocyte: SRP027529
Gametocyte: ERP004598
Gametocyte (male): SRP099925
Gametocyte (female): SRP099925
Gametocyte ap2-o KO: SRP073801
Gametocyte ap2-o2 KO: SRP073801
Gametocyte ap2-o3 KO: SRP073801
Gametocyte, ppm5 KO: ERP004598
Gametocyte (male), PbSR-MG KO: SRP109709
Gametocyte (female), PbSR-MG KO: SRP109709
Ookinete, WT: SRP073801
Ookinete, WT: ERP004740
Ookinete ap2-o KO: SRP073801
Ookinete ap2-o2 KO: SRP073801
Ookinete ap2-o3 KO: SRP073801
Ookinete, mutant: ERP004740
50.95 46.7 185.64 216.22 108.73 83.46 44.2 44.64 122.04 0.0 144.24 67.44 36.68 97.55 108.1 113.72 163.15 200.99 172.65 82.34 70.4 91.68 90.8 102.89 45.52 39.95 55.78 36.78 20.37 37.37 21.84 72.29 64.16 66.35 25.13 38.54 16.88 65.94 37.58 169.69 86.12 61.53 15.05
20.97 21.82 386.45 393.78 266.82 142.15 8.92 7.34 104.41 8.19 267.28 68.52 19.22 481.43 328.35 224.27 465.54 346.66 327.67 281.79 120.97 152.76 172.87 231.41 18.26 16.8 91.16 37.77 4.65 14.18 5.89 147.66 120.18 105.75 6.76 15.21 4.13 30.5 10.5 164.9 97.18 16.5 6.82
31.54 27.77 95.56 89.33 64.89 57.44 5.38 9.07 57.92 0.0 55.51 30.2 19.7 25.9 40.82 44.39 41.27 60.5 47.37 39.32 33.89 43.6 45.25 49.36 23.32 21.79 34.1 15.82 14.03 11.99 12.62 35.0 18.97 31.82 14.3 8.01 12.12 22.13 3.78 63.47 45.86 32.89 2.4
19.06 18.27 87.67 53.67 51.8 38.28 6.09 10.96 53.01 0.0 54.13 11.34 6.17 16.31 29.4 39.09 29.88 102.07 61.48 22.97 22.32 33.43 33.26 32.3 5.21 9.12 18.87 17.36 1.96 25.09 8.16 26.11 27.42 23.34 6.57 25.18 3.63 23.23 7.42 43.73 49.49 22.73 2.76
32.53 35.72 147.93 103.92 107.37 78.41 13.2 21.13 84.56 0.0 59.23 22.91 11.92 28.7 49.06 54.7 42.79 99.62 74.63 39.23 26.97 47.44 52.72 54.6 14.35 15.9 21.81 12.74 4.42 10.49 4.93 33.95 39.34 8.79 6.66 5.01 4.67 19.69 6.72 51.96 51.62 21.51 1.79
22.0 15.31 161.66 172.86 110.88 59.16 12.83 7.49 46.03 0.0 73.7 9.93 7.64 100.42 120.35 117.51 94.54 75.3 73.29 46.84 28.35 34.2 38.53 45.49 12.17 8.88 28.26 18.86 3.07 23.31 7.77 39.67 59.62 59.66 3.9 24.28 2.63 43.69 9.3 66.63 94.68 40.73 6.22
32.31 29.41 155.09 191.28 73.55 80.46 6.34 4.28 177.62 0.0 92.93 94.39 19.0 48.76 56.31 69.62 53.12 103.09 89.67 74.57 60.55 71.16 78.8 87.07 20.74 22.36 51.98 72.19 18.1 13.24 10.68 60.49 51.83 51.01 17.71 7.6 15.8 17.3 3.22 55.89 43.31 18.73 2.05
133.66 143.4 262.58 255.33 144.97 144.53 11.87 21.39 267.19 0.0 108.88 105.83 73.51 30.16 61.16 96.26 66.46 141.69 106.68 77.34 92.59 109.29 124.07 116.56 66.32 82.0 95.39 87.23 87.19 43.27 68.0 105.05 133.71 23.97 74.28 28.15 92.81 28.13 23.59 74.44 92.38 19.34 9.58
11.1 10.2 41.76 27.84 25.39 15.46 1.25 2.4 37.88 0.0 21.69 6.41 4.29 3.61 7.42 18.26 10.82 27.33 15.96 12.89 17.37 14.58 16.5 18.44 2.39 5.37 13.87 19.58 2.32 8.65 6.58 19.81 25.12 12.32 3.59 8.15 5.74 9.6 1.16 13.56 18.99 8.1 0.82
7.87 6.78 142.62 230.25 87.87 67.65 6.32 3.92 57.26 0.0 85.13 33.27 8.76 127.82 88.04 58.28 179.33 94.91 102.08 94.36 40.15 40.53 60.81 75.63 10.48 7.49 69.86 24.41 4.55 10.98 3.91 117.47 91.49 103.71 3.76 10.58 1.64 18.05 4.42 52.22 44.33 8.75 4.63
133.78 139.78 338.16 364.65 167.39 175.63 38.47 46.37 300.1 0.0 187.01 171.52 101.91 129.26 152.28 183.77 166.7 163.85 178.66 153.59 134.51 173.52 187.84 213.04 116.89 101.48 81.21 124.46 75.4 68.19 59.87 126.69 108.55 82.35 69.12 64.46 70.5 52.53 55.2 165.44 95.15 33.22 20.06
15.26 15.37 133.2 193.12 94.39 58.41 21.87 19.56 39.35 7.15 108.33 37.08 12.23 179.34 168.87 103.63 224.48 145.49 113.14 133.69 76.33 100.53 107.48 116.5 16.39 11.46 46.11 21.26 4.8 12.56 6.8 70.14 60.97 58.59 6.39 17.93 4.55 73.6 15.19 107.99 84.25 61.1 14.77
54.55 64.87 130.48 167.27 67.81 65.16 14.59 17.28 79.77 0.0 65.33 74.66 32.43 28.14 57.06 64.32 41.16 69.78 70.85 83.08 46.08 64.98 75.69 85.3 35.16 38.27 40.4 29.09 14.06 62.08 25.3 51.01 65.12 47.71 20.43 78.78 13.0 28.62 10.73 62.6 59.3 23.83 4.49
63.29 60.21 195.87 187.34 115.91 94.34 32.47 63.67 123.02 0.0 100.87 66.06 22.5 36.33 67.08 106.78 59.17 113.95 99.36 78.63 57.47 84.19 94.31 97.72 24.48 29.76 33.53 26.59 9.3 17.85 9.57 47.04 41.34 24.28 14.92 14.55 10.25 46.71 26.47 164.66 84.95 25.66 11.38
94.81 99.71 375.41 356.0 211.76 197.25 11.36 15.72 227.65 0.0 172.57 117.27 37.0 43.81 93.02 148.41 58.54 159.64 157.55 124.05 97.48 137.21 149.19 178.83 36.43 48.07 71.15 47.91 16.14 32.54 18.52 98.31 84.59 54.72 26.35 27.73 18.23 29.24 15.59 164.52 74.04 16.46 4.09
100.88 95.4 337.78 339.95 195.77 213.69 54.17 42.04 185.35 0.0 120.84 69.3 43.86 36.99 79.46 118.84 68.54 167.7 132.12 75.67 70.32 101.64 112.97 116.44 37.94 53.92 42.02 35.84 21.14 32.74 19.41 51.11 41.16 41.83 31.71 25.99 22.89 93.55 51.99 182.22 117.95 52.16 42.77
41.47 34.33 267.34 419.54 148.74 108.95 18.86 20.64 105.01 3.1 241.58 135.89 29.58 305.32 255.48 196.93 367.61 265.72 276.78 226.16 123.87 136.88 158.86 199.16 39.86 31.37 97.09 46.19 9.4 29.96 14.15 123.03 129.51 124.31 13.15 31.23 11.16 52.7 13.23 160.5 103.84 33.74 13.52
14.59 11.84 76.76 86.91 52.66 31.62 11.35 10.75 25.98 0.0 61.92 19.34 6.66 43.07 53.17 47.45 66.75 79.77 62.63 43.33 32.48 37.76 38.75 44.42 7.74 8.03 28.58 14.95 5.97 8.71 6.16 39.08 35.35 18.39 6.6 9.8 5.08 24.06 6.81 37.82 34.58 25.74 9.09
77.27 78.01 279.2 217.62 128.65 118.72 1.2 1.2 312.39 0.0 122.75 189.47 37.26 28.22 38.49 107.81 42.22 174.19 145.29 91.06 59.79 92.82 105.43 131.58 31.06 47.66 26.49 12.35 5.13 34.92 8.86 37.53 92.08 43.39 12.02 23.8 3.38 16.66 0.75 81.61 109.55 17.42 0.67
96.53 127.8 394.45 426.05 196.12 177.62 19.95 22.72 250.69 0.0 181.99 66.41 53.79 124.87 134.18 160.21 156.41 224.91 195.53 124.28 89.82 118.53 128.77 159.31 61.89 59.56 70.49 67.01 30.49 44.54 25.71 105.68 89.21 49.24 30.66 36.94 25.43 37.14 24.19 145.08 83.83 27.11 9.14
29.71 37.31 149.22 151.96 89.52 68.03 10.98 16.58 98.5 0.0 75.43 26.33 11.0 29.98 44.37 88.83 43.62 81.74 76.89 78.79 60.39 82.65 85.52 101.74 12.61 13.69 50.78 28.05 6.2 21.76 9.67 78.86 65.34 75.71 8.73 22.06 6.38 27.84 9.09 94.09 61.85 27.05 4.35
52.81 59.98 296.38 346.11 163.24 139.92 10.62 13.34 160.75 0.44 143.29 113.36 49.18 119.55 116.76 104.62 148.33 145.13 160.17 126.51 66.79 85.38 109.75 135.24 55.54 49.57 62.95 39.49 21.88 52.36 19.45 90.07 87.59 81.66 19.18 56.48 9.58 19.05 10.26 96.93 58.39 10.5 3.89
21.42 19.72 159.36 156.31 99.9 66.59 9.29 6.71 61.02 0.19 106.4 24.19 7.05 126.63 88.04 77.66 121.06 143.31 130.28 89.41 58.45 65.92 72.39 84.93 8.22 9.19 45.41 16.76 2.79 10.65 5.72 64.1 51.82 54.43 5.56 11.02 4.68 25.91 6.65 99.41 53.39 19.82 7.51
59.61 61.35 197.3 145.67 108.14 99.68 4.92 3.74 227.44 0.0 99.55 74.56 20.85 26.93 58.94 65.86 49.87 130.4 162.95 54.81 34.27 56.92 72.95 77.39 20.88 25.21 35.6 13.4 9.24 32.92 11.69 42.05 87.56 83.67 10.22 28.36 6.35 14.23 3.56 61.72 44.34 12.78 2.2
14.92 13.34 146.12 142.9 83.84 58.82 5.79 7.24 39.29 0.0 101.55 49.75 9.22 101.38 105.61 69.01 130.51 121.65 106.28 92.06 60.04 75.14 84.89 102.65 11.34 10.18 48.25 21.47 3.22 7.6 4.35 81.63 65.94 59.92 5.73 7.21 4.81 22.78 7.85 91.16 59.42 21.31 4.67
382.37 463.17 776.82 723.96 448.93 467.92 136.51 197.59 925.18 0.0 438.17 359.98 234.6 298.82 488.18 474.82 276.33 403.53 500.63 368.47 298.61 431.04 410.62 416.34 314.74 264.94 250.45 212.35 132.49 380.05 166.7 298.29 355.83 386.72 168.8 413.94 80.05 209.96 65.07 531.16 288.31 150.6 35.81
14.53 13.14 75.4 94.54 39.72 34.99 3.95 8.39 47.25 0.0 42.23 29.23 11.28 29.82 36.05 32.77 51.05 43.3 41.67 40.1 28.4 29.19 37.1 45.03 13.39 12.3 33.57 19.91 7.33 8.79 6.12 63.85 40.09 29.51 7.73 8.57 5.87 11.51 4.96 51.68 24.4 7.14 1.75
11.46 9.34 144.32 152.2 97.31 61.43 18.12 14.05 40.84 1.28 83.14 14.89 3.59 53.38 54.87 86.96 76.15 130.05 102.01 64.58 34.62 52.03 47.11 60.47 2.89 5.29 26.42 8.68 0.74 7.58 2.32 50.13 58.18 47.77 1.8 7.74 1.35 47.71 17.17 54.19 100.35 34.26 14.65
117.14 134.41 497.27 377.98 280.82 248.57 141.76 63.62 241.78 0.0 435.91 143.44 100.85 307.88 279.22 362.6 341.69 490.98 443.62 292.14 225.18 305.86 292.24 334.3 109.36 113.55 145.21 78.11 76.3 57.91 46.87 152.9 137.1 201.25 55.68 43.27 45.86 276.47 68.78 269.11 352.42 230.61 74.5
15.86 12.84 256.3 338.17 173.09 112.36 4.16 4.4 44.29 0.0 171.67 23.79 12.89 256.47 216.21 219.07 375.82 227.41 202.01 149.64 67.32 93.48 102.61 127.46 20.56 12.68 82.4 18.22 4.79 16.79 6.38 120.75 139.62 135.28 4.91 19.68 2.55 27.2 4.6 121.16 82.49 22.05 2.42
64.07 61.5 222.1 245.75 111.27 98.42 26.0 19.28 252.45 0.0 123.49 333.12 63.99 50.15 87.17 110.13 91.16 118.6 117.12 133.04 81.58 126.82 141.56 168.86 73.81 66.71 30.49 46.73 19.52 28.57 13.6 42.03 38.95 22.08 21.87 18.87 10.84 42.16 34.18 107.19 102.67 26.91 14.01
23.54 22.29 238.85 223.15 127.77 74.08 2.89 4.51 59.68 0.0 63.99 17.17 6.68 37.01 63.53 52.98 74.22 90.69 71.76 47.06 32.93 48.52 50.68 61.64 6.22 8.12 33.51 11.32 3.21 8.23 3.49 50.42 42.68 10.69 4.01 4.81 4.04 13.07 4.07 88.49 42.89 7.26 1.72
28.33 25.04 148.36 114.32 175.83 125.66 0.0 1.86 70.28 0.0 51.13 37.04 4.79 18.73 41.58 54.1 40.68 100.69 63.14 40.11 25.79 52.6 54.74 58.39 2.32 8.18 10.03 6.65 0.17 6.16 3.8 26.74 16.3 13.61 1.27 4.18 1.69 5.96 1.41 47.39 30.03 7.55 0.0
14.33 13.68 50.55 46.46 26.03 20.32 3.18 2.86 32.64 0.0 22.85 8.15 5.02 13.62 27.11 16.58 23.63 28.23 23.36 15.37 15.55 21.95 24.1 25.57 7.0 6.37 12.01 10.62 2.97 8.4 5.52 15.04 23.62 9.71 4.3 6.95 5.45 11.59 2.51 18.57 32.07 6.9 2.16
43.77 48.28 284.64 266.92 143.09 112.36 2.81 3.72 145.54 0.0 133.36 101.93 21.48 52.81 105.82 116.34 78.55 152.31 147.5 110.6 66.78 109.01 129.62 155.34 22.24 26.68 46.97 24.66 6.04 28.23 11.44 68.93 70.14 71.68 10.81 27.28 6.58 15.89 5.37 95.55 55.02 10.07 2.73
37.18 35.85 189.4 185.84 100.52 82.15 4.61 4.84 115.96 0.0 94.64 38.57 23.91 60.4 72.27 86.95 82.89 105.43 95.06 80.35 66.08 70.6 77.5 90.69 27.84 25.4 74.13 49.49 19.56 19.86 13.6 104.97 75.6 84.08 14.48 20.51 12.87 17.01 5.01 60.58 38.47 14.88 2.81
43.1 36.89 178.71 231.46 102.01 112.49 30.63 47.27 91.93 0.0 103.38 61.09 27.81 30.43 51.66 88.61 53.72 107.5 95.11 77.95 86.32 85.88 94.68 100.49 26.84 31.96 82.28 57.25 28.06 51.83 29.61 95.26 109.63 86.39 30.32 51.72 26.23 44.22 22.73 96.55 64.49 26.43 11.93
246.71 254.27 577.92 604.13 249.21 281.49 43.58 58.8 555.99 0.0 305.58 296.41 134.32 169.88 255.17 310.86 140.29 252.05 312.46 260.87 181.48 301.49 286.65 319.09 148.0 142.2 107.89 80.99 53.04 162.45 63.29 120.92 129.71 146.46 58.98 136.36 38.86 94.04 20.87 216.72 119.58 55.58 11.11
9.38 8.34 66.11 54.72 53.65 25.4 7.55 15.64 38.16 0.0 62.52 9.88 5.38 77.79 65.83 45.97 89.97 78.43 62.61 53.64 25.61 33.87 32.58 36.17 5.14 5.87 15.24 12.52 1.62 3.55 1.74 22.29 21.34 11.61 1.96 2.19 1.93 32.32 8.31 53.19 32.69 23.79 5.12
120.61 106.53 295.82 356.89 192.67 194.25 103.58 188.4 207.41 0.0 118.3 74.49 61.87 29.82 52.57 135.07 50.36 147.08 106.65 90.19 95.35 111.22 116.73 127.37 48.17 73.38 66.7 61.84 46.49 54.65 43.97 85.74 67.01 68.48 66.63 37.27 52.52 87.37 93.15 157.76 110.56 89.19 36.5
PBANKA_1357200 (GRP170)
 266.48 275.06 777.91 764.15 377.95 504.67 42.62 74.23 667.65 0.0 296.34 473.16 159.79 158.42 169.24 232.81 250.25 291.63 347.39 265.12 175.58 235.13 287.63 343.5 158.43 171.53 151.29 108.98 76.99 117.31 64.88 173.18 157.02 147.56 92.45 92.26 60.15 76.16 45.66 313.13 178.19 69.75 17.61
43.09 40.22 239.88 241.92 157.93 127.27 31.29 34.45 116.44 0.0 105.16 42.15 15.46 30.13 84.0 102.29 53.39 114.67 105.06 79.7 83.59 90.78 104.44 118.42 16.04 20.37 90.69 45.35 11.96 24.97 16.57 129.26 107.34 81.77 16.01 26.03 13.33 65.88 28.52 165.15 96.44 36.77 11.27
19.81 18.16 46.74 47.93 29.0 21.67 4.51 7.41 29.7 0.0 21.32 22.28 6.92 4.24 8.05 20.68 10.88 22.28 15.09 20.48 16.51 22.39 24.44 26.95 6.95 9.04 15.83 10.39 3.8 18.34 6.71 27.6 25.76 25.88 4.81 17.24 3.46 9.08 3.17 22.75 15.01 9.51 1.89
25.57 23.3 66.3 68.17 36.19 28.07 3.07 4.58 45.49 0.0 47.38 29.32 13.58 22.58 36.67 43.93 29.58 47.41 37.79 38.07 37.17 44.58 43.65 46.8 11.49 17.47 37.57 21.9 5.95 12.08 9.92 42.32 39.14 32.01 11.89 10.38 11.86 15.78 4.6 42.01 29.49 21.95 2.25
17.5 14.21 89.53 70.81 46.71 41.22 3.0 7.46 40.28 0.0 31.63 17.63 6.04 5.77 11.6 39.87 12.62 43.25 26.55 26.65 19.38 28.77 28.79 31.08 7.0 8.14 23.65 9.74 7.86 28.12 11.82 38.73 50.79 38.09 9.66 28.1 4.72 12.09 2.51 16.68 20.3 13.57 1.2
64.48 64.06 258.77 294.1 118.33 141.19 1.4 1.4 152.8 0.0 114.15 66.79 25.65 95.84 91.84 105.01 87.45 143.94 125.36 85.78 46.76 82.68 86.98 99.43 30.96 31.92 11.19 11.06 4.63 17.51 6.33 16.03 39.79 14.19 8.59 11.75 5.24 14.32 1.71 62.79 60.15 16.21 0.8
220.11 203.04 903.48 666.3 469.82 346.72 5.66 10.45 639.54 2.89 265.05 183.42 73.2 85.87 180.22 237.54 164.88 435.58 398.53 172.16 128.3 207.96 231.99 285.09 63.36 85.61 56.59 70.35 20.57 121.67 40.9 115.91 118.22 108.48 30.27 117.18 17.74 24.35 11.7 168.82 96.01 23.15 3.07
38.86 38.33 194.09 192.34 107.33 98.98 7.21 9.85 205.62 0.0 144.36 101.36 22.12 99.44 92.94 154.49 160.17 136.6 138.08 148.99 60.54 85.6 104.33 123.51 20.09 30.83 65.96 31.55 7.89 18.3 8.71 92.62 123.02 69.96 11.85 10.42 8.65 33.58 6.56 113.21 82.11 19.32 2.95
31.85 29.08 367.56 425.82 225.74 161.48 45.79 24.39 109.93 0.0 145.06 101.13 18.64 94.1 136.37 154.68 151.78 174.51 139.52 161.05 97.34 139.58 156.86 193.34 20.56 20.35 74.92 32.39 10.72 14.7 9.55 122.5 81.64 62.13 10.84 12.08 10.18 74.77 50.94 177.42 136.8 24.42 44.0

Details

Raw expression values (TPM normalized), Green cells indicate low expression and red high. (Dark gray cells indicate missing values)