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  5. PF3D7_0214000

PF3D7_0214000 (CCT8)


Aliases : CCT8

Description : SSF54849: TCP-1-like chaperonin intermediate domain superfamily, SSF48592: GroEL-like equatorial domain superfamily, SSF52029: GroEL-like apical domain superfamily. Pfam domain(s): PF00118: TCP-1/cpn60 chaperonin family.


Gene families : OG_01_0000575 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000575_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0214000
Cluster P. falciparum: Cluster_38

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0310900 CCT8 SSF52029: GroEL-like apical domain superfamily,... 0.07 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IPI PlasmoDB
MF GO:0005524 ATP binding IEA Interproscan predictions
MF GO:0005524 ATP binding IEA PlasmoDB
CC GO:0005829 cytosol IDA PlasmoDB
CC GO:0005832 chaperonin-containing T-complex IDA PlasmoDB
BP GO:0006457 protein folding ISS PlasmoDB
BP GO:0006457 protein folding IEA PlasmoDB
CC GO:0030430 host cell cytoplasm IDA PlasmoDB
CC GO:0045177 apical part of cell IDA PlasmoDB
MF GO:0051082 unfolded protein binding IEA PlasmoDB
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Type GO Term Name Evidence Source
BP GO:0000027 ribosomal large subunit assembly IEP Predicted GO
BP GO:0000054 ribosomal subunit export from nucleus IEP Predicted GO
BP GO:0000055 ribosomal large subunit export from nucleus IEP Predicted GO
MF GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
CC GO:0000428 DNA-directed RNA polymerase complex IEP Predicted GO
MF GO:0002161 aminoacyl-tRNA editing activity IEP Predicted GO
BP GO:0002181 cytoplasmic translation IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003724 RNA helicase activity IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003883 CTP synthase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0003921 GMP synthase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0003963 RNA-3'-phosphate cyclase activity IEP Predicted GO
MF GO:0004004 ATP-dependent RNA helicase activity IEP Predicted GO
MF GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0004164 diphthine synthase activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004347 glucose-6-phosphate isomerase activity IEP Predicted GO
MF GO:0004364 glutathione transferase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004802 transketolase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004813 alanine-tRNA ligase activity IEP Predicted GO
MF GO:0004815 aspartate-tRNA ligase activity IEP Predicted GO
MF GO:0004818 glutamate-tRNA ligase activity IEP Predicted GO
MF GO:0004820 glycine-tRNA ligase activity IEP Predicted GO
MF GO:0004822 isoleucine-tRNA ligase activity IEP Predicted GO
MF GO:0004824 lysine-tRNA ligase activity IEP Predicted GO
MF GO:0004832 valine-tRNA ligase activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005654 nucleoplasm IEP Predicted GO
CC GO:0005666 RNA polymerase III complex IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
BP GO:0006002 fructose 6-phosphate metabolic process IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006109 regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006241 CTP biosynthetic process IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006360 transcription by RNA polymerase I IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006383 transcription by RNA polymerase III IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006419 alanyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006422 aspartyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006424 glutamyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006426 glycyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006428 isoleucyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006430 lysyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006438 valyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006538 glutamate catabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006733 oxidoreduction coenzyme metabolic process IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0007050 cell cycle arrest IEP Predicted GO
MF GO:0008026 ATP-dependent helicase activity IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0008186 RNA-dependent ATPase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008238 exopeptidase activity IEP Predicted GO
BP GO:0008283 cell proliferation IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009065 glutamine family amino acid catabolic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009304 tRNA transcription IEP Predicted GO
BP GO:0010322 regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010323 negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010501 RNA secondary structure unwinding IEP Predicted GO
BP GO:0010563 negative regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0010565 regulation of cellular ketone metabolic process IEP Predicted GO
BP GO:0010675 regulation of cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0010677 negative regulation of cellular carbohydrate metabolic process IEP Predicted GO
MF GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0015959 diadenosine polyphosphate metabolic process IEP Predicted GO
BP GO:0015960 diadenosine polyphosphate biosynthetic process IEP Predicted GO
BP GO:0015965 diadenosine tetraphosphate metabolic process IEP Predicted GO
BP GO:0015966 diadenosine tetraphosphate biosynthetic process IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
CC GO:0016281 eukaryotic translation initiation factor 4F complex IEP Predicted GO
CC GO:0016324 apical plasma membrane IEP Predicted GO
MF GO:0016433 rRNA (adenine) methyltransferase activity IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016744 transferase activity, transferring aldehyde or ketonic groups IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
MF GO:0019203 carbohydrate phosphatase activity IEP Predicted GO
BP GO:0019216 regulation of lipid metabolic process IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019362 pyridine nucleotide metabolic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019747 regulation of isoprenoid metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
BP GO:0022618 ribonucleoprotein complex assembly IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
MF GO:0030515 snoRNA binding IEP Predicted GO
MF GO:0030621 U4 snRNA binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
CC GO:0030686 90S preribosome IEP Predicted GO
CC GO:0030687 preribosome, large subunit precursor IEP Predicted GO
CC GO:0030688 preribosome, small subunit precursor IEP Predicted GO
CC GO:0030880 RNA polymerase complex IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
CC GO:0031428 box C/D snoRNP complex IEP Predicted GO
BP GO:0031503 protein-containing complex localization IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
MF GO:0033677 DNA/RNA helicase activity IEP Predicted GO
MF GO:0033679 3'-5' DNA/RNA helicase activity IEP Predicted GO
BP GO:0033750 ribosome localization IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
MF GO:0034511 U3 snoRNA binding IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
BP GO:0042797 tRNA transcription by RNA polymerase III IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
MF GO:0043139 5'-3' DNA helicase activity IEP Predicted GO
MF GO:0043141 ATP-dependent 5'-3' DNA helicase activity IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0043649 dicarboxylic acid catabolic process IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044452 nucleolar part IEP Predicted GO
BP GO:0045827 negative regulation of isoprenoid metabolic process IEP Predicted GO
BP GO:0045833 negative regulation of lipid metabolic process IEP Predicted GO
BP GO:0045912 negative regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0045936 negative regulation of phosphate metabolic process IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046036 CTP metabolic process IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0046496 nicotinamide nucleotide metabolic process IEP Predicted GO
BP GO:0046890 regulation of lipid biosynthetic process IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity IEP Predicted GO
BP GO:0048523 negative regulation of cellular process IEP Predicted GO
MF GO:0050308 sugar-phosphatase activity IEP Predicted GO
BP GO:0051055 negative regulation of lipid biosynthetic process IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051656 establishment of organelle localization IEP Predicted GO
BP GO:0051726 regulation of cell cycle IEP Predicted GO
MF GO:0052689 carboxylic ester hydrolase activity IEP Predicted GO
CC GO:0055029 nuclear DNA-directed RNA polymerase complex IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
BP GO:0062012 regulation of small molecule metabolic process IEP Predicted GO
BP GO:0062014 negative regulation of small molecule metabolic process IEP Predicted GO
MF GO:0070035 purine NTP-dependent helicase activity IEP Predicted GO
BP GO:0071071 regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071072 negative regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071426 ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071826 ribonucleoprotein complex subunit organization IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072524 pyridine-containing compound metabolic process IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
CC GO:0098590 plasma membrane region IEP Predicted GO
BP GO:0098781 ncRNA transcription IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
BP GO:1903725 regulation of phospholipid metabolic process IEP Predicted GO
BP GO:1903726 negative regulation of phospholipid metabolic process IEP Predicted GO
CC GO:1990234 transferase complex IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR002423 Cpn60/TCP-1 36 525
PlasmoDB 812727
PlasmoDB PF02_0131
PlasmoDB PFB0635w