PF3D7_0217500 (CDPK1)

Aliases : CDPK1

Description : SSF56112: Protein kinase-like domain superfamily, SSF47473: EF-hand domain pair. Pfam domain(s): PF13499: EF-hand domain pair, PF00069: Protein kinase domain.

Gene families : OG_01_0000029 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000029_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0217500
Cluster	P. falciparum: Cluster_20

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0314200	CDPK1	SSF56112: Protein kinase-like domain superfamily,...	0.08	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0004674	protein serine/threonine kinase activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005509	calcium ion binding	IEA	Interproscan predictions
MF	GO:0005509	calcium ion binding	IEA	PlasmoDB
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005886	plasma membrane	IDA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	IDA	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0009931	calcium-dependent protein serine/threonine kinase activity	IDA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
MF	GO:0010857	calcium-dependent protein kinase activity	None	Extended
CC	GO:0016020	membrane	IDA	PlasmoDB
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020003	symbiont-containing vacuole	IDA	PlasmoDB
CC	GO:0020005	symbiont-containing vacuole membrane	IDA	PlasmoDB
BP	GO:0030260	entry into host cell	IMP	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
BP	GO:0035890	exit from host	None	Extended
BP	GO:0035891	exit from host cell	IMP	PlasmoDB
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0040011	locomotion	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
CC	GO:0044217	other organism part	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0044409	entry into host	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051828	entry into other organism involved in symbiotic interaction	None	Extended
BP	GO:0052126	movement in host environment	None	Extended
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	None	Extended
CC	GO:0065010	extracellular membrane-bounded organelle	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003823	antigen binding	IEP	Predicted GO
MF	GO:0004016	adenylate cyclase activity	IEP	Predicted GO
MF	GO:0004103	choline kinase activity	IEP	Predicted GO
MF	GO:0004383	guanylate cyclase activity	IEP	Predicted GO
MF	GO:0004690	cyclic nucleotide-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004692	cGMP-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0005096	GTPase activator activity	IEP	Predicted GO
CC	GO:0005884	actin filament	IEP	Predicted GO
BP	GO:0006182	cGMP biosynthetic process	IEP	Predicted GO
BP	GO:0006656	phosphatidylcholine biosynthetic process	IEP	Predicted GO
BP	GO:0007165	signal transduction	IEP	Predicted GO
BP	GO:0007265	Ras protein signal transduction	IEP	Predicted GO
BP	GO:0007266	Rho protein signal transduction	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
BP	GO:0009187	cyclic nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009190	cyclic nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009268	response to pH	IEP	Predicted GO
MF	GO:0009975	cyclase activity	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0015095	magnesium ion transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015693	magnesium ion transport	IEP	Predicted GO
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
CC	GO:0020008	rhoptry	IEP	Predicted GO
MF	GO:0030234	enzyme regulator activity	IEP	Predicted GO
MF	GO:0030695	GTPase regulator activity	IEP	Predicted GO
CC	GO:0033016	rhoptry membrane	IEP	Predicted GO
MF	GO:0033265	choline binding	IEP	Predicted GO
BP	GO:0035556	intracellular signal transduction	IEP	Predicted GO
MF	GO:0042165	neurotransmitter binding	IEP	Predicted GO
CC	GO:0042643	actomyosin, actin portion	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0045121	membrane raft	IEP	Predicted GO
BP	GO:0046068	cGMP metabolic process	IEP	Predicted GO
BP	GO:0046470	phosphatidylcholine metabolic process	IEP	Predicted GO
BP	GO:0052652	cyclic purine nucleotide metabolic process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070405	ammonium ion binding	IEP	Predicted GO
BP	GO:0070838	divalent metal ion transport	IEP	Predicted GO
BP	GO:0072511	divalent inorganic cation transport	IEP	Predicted GO
CC	GO:0098589	membrane region	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
CC	GO:0098857	membrane microdomain	IEP	Predicted GO
CC	GO:0099080	supramolecular complex	IEP	Predicted GO
CC	GO:0099081	supramolecular polymer	IEP	Predicted GO
CC	GO:0099512	supramolecular fiber	IEP	Predicted GO
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990225	rhoptry neck	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002048	EF_hand_dom	454	515
IPR002048	EF_hand_dom	375	444
IPR000719	Prot_kinase_dom	58	325

External Links

PlasmoDB	812762
PlasmoDB	PF02_0166
PlasmoDB	PFB0815w

PF3D7_0217500 (CDPK1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation