PF3D7_0512200 (GS)

Aliases : GS

Description : SSF56059: No description available, SSF52440: Pre-ATP-grasp domain superfamily. Pfam domain(s): PF03199: Eukaryotic glutathione synthase, PF03917: "Eukaryotic glutathione synthase, ATP binding domain".

Gene families : OG_01_0000208 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000208_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0512200
Cluster	P. falciparum: Cluster_14

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1111800	GS	SSF56059: 20-02-2019. Pfam domain(s): PF03199:...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004363	glutathione synthase activity	ISS	PlasmoDB
MF	GO:0004363	glutathione synthase activity	IEA	Interproscan predictions
MF	GO:0004363	glutathione synthase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	ISS	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006518	peptide metabolic process	None	Extended
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006749	glutathione metabolic process	None	Extended
BP	GO:0006750	glutathione biosynthetic process	ISS	PlasmoDB
BP	GO:0006750	glutathione biosynthetic process	IEA	Interproscan predictions
BP	GO:0006750	glutathione biosynthetic process	IEA	PlasmoDB
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006979	response to oxidative stress	ISS	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	None	Extended
MF	GO:0016881	acid-amino acid ligase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019184	nonribosomal peptide biosynthetic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0043043	peptide biosynthetic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	Predicted GO
BP	GO:0001775	cell activation	IEP	Predicted GO
MF	GO:0004661	protein geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0004663	Rab geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0005194	obsolete cell adhesion molecule activity	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005968	Rab-protein geranylgeranyltransferase complex	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008192	RNA guanylyltransferase activity	IEP	Predicted GO
MF	GO:0008193	tRNA guanylyltransferase activity	IEP	Predicted GO
MF	GO:0008318	protein prenyltransferase activity	IEP	Predicted GO
MF	GO:0008479	queuine tRNA-ribosyltransferase activity	IEP	Predicted GO
BP	GO:0009106	lipoate metabolic process	IEP	Predicted GO
BP	GO:0009107	lipoate biosynthetic process	IEP	Predicted GO
BP	GO:0009249	protein lipoylation	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
BP	GO:0009966	regulation of signal transduction	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0010646	regulation of cell communication	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016866	intramolecular transferase activity	IEP	Predicted GO
MF	GO:0016979	lipoate-protein ligase activity	IEP	Predicted GO
BP	GO:0018065	protein-cofactor linkage	IEP	Predicted GO
BP	GO:0018205	peptidyl-lysine modification	IEP	Predicted GO
BP	GO:0018344	protein geranylgeranylation	IEP	Predicted GO
BP	GO:0020012	evasion or tolerance of host immune response	IEP	Predicted GO
BP	GO:0023051	regulation of signaling	IEP	Predicted GO
BP	GO:0030682	evasion or tolerance of host defense response	IEP	Predicted GO
MF	GO:0033819	lipoyl(octanoyl) transferase activity	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0042113	B cell activation	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0044413	avoidance of host defenses	IEP	Predicted GO
BP	GO:0044415	evasion or tolerance of host defenses	IEP	Predicted GO
BP	GO:0045321	leukocyte activation	IEP	Predicted GO
BP	GO:0046649	lymphocyte activation	IEP	Predicted GO
BP	GO:0051604	protein maturation	IEP	Predicted GO
BP	GO:0052200	response to host defenses	IEP	Predicted GO
BP	GO:0052572	response to host immune response	IEP	Predicted GO
MF	GO:0070568	guanylyltransferase activity	IEP	Predicted GO
BP	GO:0075136	response to host	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004887	GSH_synth_subst-bd	290	445
IPR005615	Glutathione_synthase	35	652

External Links

PlasmoDB	812930
PlasmoDB	MAL5P1.122
PlasmoDB	PFE0605c

PF3D7_0512200 (GS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation