PF3D7_0610800 (TK)


Aliases : TK

Description : SSF52518: Thiamin diphosphate-binding fold, SSF52922: Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II. Pfam domain(s): PF00456: "Transketolase, thiamine diphosphate binding domain", PF02779: "Transketolase, pyrimidine binding domain".


Gene families : OG_01_0002287 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002287_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0610800
Cluster P. falciparum: Cluster_38


Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA PlasmoDB
MF GO:0004802 transketolase activity IDA PlasmoDB
MF GO:0004802 transketolase activity IEA PlasmoDB
CC GO:0005634 nucleus IDA PlasmoDB
CC GO:0005737 cytoplasm IDA PlasmoDB
BP GO:0006098 pentose-phosphate shunt ISS PlasmoDB
BP GO:0008152 metabolic process IEA PlasmoDB
Type GO Term Name Evidence Source
BP GO:0000027 ribosomal large subunit assembly IEP Predicted GO
BP GO:0000054 ribosomal subunit export from nucleus IEP Predicted GO
BP GO:0000055 ribosomal large subunit export from nucleus IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity IEP Predicted GO
MF GO:0000295 adenine nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
BP GO:0002181 cytoplasmic translation IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003724 RNA helicase activity IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003883 CTP synthase activity IEP Predicted GO
MF GO:0003921 GMP synthase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0004004 ATP-dependent RNA helicase activity IEP Predicted GO
MF GO:0004019 adenylosuccinate synthase activity IEP Predicted GO
MF GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004364 glutathione transferase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004813 alanine-tRNA ligase activity IEP Predicted GO
MF GO:0004824 lysine-tRNA ligase activity IEP Predicted GO
MF GO:0004829 threonine-tRNA ligase activity IEP Predicted GO
MF GO:0004832 valine-tRNA ligase activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005346 purine ribonucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0005347 ATP transmembrane transporter activity IEP Predicted GO
MF GO:0005471 ATP:ADP antiporter activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005654 nucleoplasm IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006002 fructose 6-phosphate metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006090 pyruvate metabolic process IEP Predicted GO
BP GO:0006096 glycolytic process IEP Predicted GO
BP GO:0006163 purine nucleotide metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006165 nucleoside diphosphate phosphorylation IEP Predicted GO
BP GO:0006167 AMP biosynthetic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006241 CTP biosynthetic process IEP Predicted GO
BP GO:0006360 transcription by RNA polymerase I IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006419 alanyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006430 lysyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006435 threonyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006438 valyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006528 asparagine metabolic process IEP Predicted GO
BP GO:0006529 asparagine biosynthetic process IEP Predicted GO
BP GO:0006757 ATP generation from ADP IEP Predicted GO
BP GO:0007050 cell cycle arrest IEP Predicted GO
MF GO:0008026 ATP-dependent helicase activity IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008186 RNA-dependent ATPase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008238 exopeptidase activity IEP Predicted GO
BP GO:0008283 cell proliferation IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
CC GO:0008537 proteasome activator complex IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009067 aspartate family amino acid biosynthetic process IEP Predicted GO
BP GO:0009123 nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009132 nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009135 purine nucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009142 nucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009150 purine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009152 purine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009166 nucleotide catabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009179 purine ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009185 ribonucleoside diphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009201 ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009259 ribonucleotide metabolic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009266 response to temperature stimulus IEP Predicted GO
BP GO:0009408 response to heat IEP Predicted GO
BP GO:0009628 response to abiotic stimulus IEP Predicted GO
BP GO:0010501 RNA secondary structure unwinding IEP Predicted GO
MF GO:0015215 nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015216 purine nucleotide transmembrane transporter activity IEP Predicted GO
MF GO:0015217 ADP transmembrane transporter activity IEP Predicted GO
MF GO:0015605 organophosphate ester transmembrane transporter activity IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0015959 diadenosine polyphosphate metabolic process IEP Predicted GO
BP GO:0015960 diadenosine polyphosphate biosynthetic process IEP Predicted GO
BP GO:0015965 diadenosine tetraphosphate metabolic process IEP Predicted GO
BP GO:0015966 diadenosine tetraphosphate biosynthetic process IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
CC GO:0016281 eukaryotic translation initiation factor 4F complex IEP Predicted GO
MF GO:0016433 rRNA (adenine) methyltransferase activity IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016879 ligase activity, forming carbon-nitrogen bonds IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0017150 tRNA dihydrouridine synthase activity IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019359 nicotinamide nucleotide biosynthetic process IEP Predicted GO
BP GO:0019363 pyridine nucleotide biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019439 aromatic compound catabolic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
BP GO:0022618 ribonucleoprotein complex assembly IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
MF GO:0030515 snoRNA binding IEP Predicted GO
MF GO:0030544 Hsp70 protein binding IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030621 U4 snRNA binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
CC GO:0030687 preribosome, large subunit precursor IEP Predicted GO
CC GO:0030688 preribosome, small subunit precursor IEP Predicted GO
MF GO:0031072 heat shock protein binding IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
BP GO:0031503 protein-containing complex localization IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033677 DNA/RNA helicase activity IEP Predicted GO
MF GO:0033679 3'-5' DNA/RNA helicase activity IEP Predicted GO
BP GO:0033750 ribosome localization IEP Predicted GO
BP GO:0034404 nucleobase-containing small molecule biosynthetic process IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
MF GO:0034511 U3 snoRNA binding IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034655 nucleobase-containing compound catabolic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0042255 ribosome assembly IEP Predicted GO
BP GO:0042256 mature ribosome assembly IEP Predicted GO
BP GO:0042273 ribosomal large subunit biogenesis IEP Predicted GO
BP GO:0042866 pyruvate biosynthetic process IEP Predicted GO
MF GO:0043023 ribosomal large subunit binding IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0043933 protein-containing complex subunit organization IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044270 cellular nitrogen compound catabolic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044421 extracellular region part IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
BP GO:0046031 ADP metabolic process IEP Predicted GO
BP GO:0046033 AMP metabolic process IEP Predicted GO
BP GO:0046036 CTP metabolic process IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046700 heterocycle catabolic process IEP Predicted GO
BP GO:0046777 protein autophosphorylation IEP Predicted GO
BP GO:0046939 nucleotide phosphorylation IEP Predicted GO
MF GO:0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051260 protein homooligomerization IEP Predicted GO
BP GO:0051262 protein tetramerization IEP Predicted GO
BP GO:0051289 protein homotetramerization IEP Predicted GO
BP GO:0051656 establishment of organelle localization IEP Predicted GO
MF GO:0051879 Hsp90 protein binding IEP Predicted GO
BP GO:0065003 protein-containing complex assembly IEP Predicted GO
MF GO:0070006 metalloaminopeptidase activity IEP Predicted GO
MF GO:0070035 purine NTP-dependent helicase activity IEP Predicted GO
BP GO:0071426 ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071826 ribonucleoprotein complex subunit organization IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072330 monocarboxylic acid biosynthetic process IEP Predicted GO
BP GO:0072521 purine-containing compound metabolic process IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0072525 pyridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901137 carbohydrate derivative biosynthetic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901292 nucleoside phosphate catabolic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901361 organic cyclic compound catabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
CC GO:1903561 extracellular vesicle IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR005475 Transketolase-like_Pyr-bd 359 529
IPR005474 Transketolase_N 9 341
PlasmoDB 2270.t00206
PlasmoDB 3885924
PlasmoDB MAL6P1.110
PlasmoDB PFF0530w