PF3D7_0623500 (SOD2)

Aliases : SOD2

Description : SSF54719: "Manganese/iron superoxide dismutase, C-terminal domain superfamily", SSF46609: "Manganese/iron superoxide dismutase, N-terminal domain superfamily". Pfam domain(s): PF00081: "Iron/manganese superoxide dismutases, alpha-hairpin domain", PF02777: "Iron/manganese superoxide dismutases, C-terminal domain".

Gene families : OG_01_0000087 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000087_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0623500
Cluster	P. falciparum: Cluster_44

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1422700	FeSOD	SSF46609: Manganese/iron superoxide dismutase,...	0.06	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004784	superoxide dismutase activity	ISS	PlasmoDB
MF	GO:0004784	superoxide dismutase activity	IEA	Interproscan predictions
MF	GO:0004784	superoxide dismutase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	IDA	PlasmoDB
BP	GO:0006801	superoxide metabolic process	IEA	Interproscan predictions
BP	GO:0006801	superoxide metabolic process	IEA	PlasmoDB
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006979	response to oxidative stress	ISS	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016209	antioxidant activity	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	None	Extended
BP	GO:0019430	removal of superoxide radicals	ISS	PlasmoDB
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	IEA	Interproscan predictions
MF	GO:0046872	metal ion binding	IEA	PlasmoDB
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0072593	reactive oxygen species metabolic process	None	Extended
BP	GO:0098754	detoxification	None	Extended
BP	GO:0098869	cellular oxidant detoxification	None	Extended
BP	GO:1990748	cellular detoxification	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
CC	GO:0000932	P-body	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003697	single-stranded DNA binding	IEP	Predicted GO
MF	GO:0003747	translation release factor activity	IEP	Predicted GO
MF	GO:0003756	protein disulfide isomerase activity	IEP	Predicted GO
MF	GO:0004550	nucleoside diphosphate kinase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005200	structural constituent of cytoskeleton	IEP	Predicted GO
MF	GO:0005216	ion channel activity	IEP	Predicted GO
MF	GO:0005253	anion channel activity	IEP	Predicted GO
MF	GO:0005254	chloride channel activity	IEP	Predicted GO
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Predicted GO
CC	GO:0005869	dynactin complex	IEP	Predicted GO
BP	GO:0006108	malate metabolic process	IEP	Predicted GO
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	Predicted GO
BP	GO:0006183	GTP biosynthetic process	IEP	Predicted GO
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0006228	UTP biosynthetic process	IEP	Predicted GO
BP	GO:0006241	CTP biosynthetic process	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006402	mRNA catabolic process	IEP	Predicted GO
BP	GO:0006415	translational termination	IEP	Predicted GO
BP	GO:0006662	glycerol ether metabolic process	IEP	Predicted GO
MF	GO:0008079	translation termination factor activity	IEP	Predicted GO
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009142	nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0015035	protein disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015036	disulfide oxidoreductase activity	IEP	Predicted GO
MF	GO:0015103	inorganic anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015108	chloride transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	IEP	Predicted GO
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Predicted GO
BP	GO:0018904	ether metabolic process	IEP	Predicted GO
BP	GO:0019439	aromatic compound catabolic process	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
MF	GO:0022838	substrate-specific channel activity	IEP	Predicted GO
MF	GO:0030060	L-malate dehydrogenase activity	IEP	Predicted GO
CC	GO:0030121	AP-1 adaptor complex	IEP	Predicted GO
MF	GO:0030508	obsolete thiol-disulfide exchange intermediate activity	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
MF	GO:0031404	chloride ion binding	IEP	Predicted GO
MF	GO:0032552	deoxyribonucleotide binding	IEP	Predicted GO
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034655	nucleobase-containing compound catabolic process	IEP	Predicted GO
CC	GO:0035770	ribonucleoprotein granule	IEP	Predicted GO
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	Predicted GO
BP	GO:0042278	purine nucleoside metabolic process	IEP	Predicted GO
BP	GO:0042451	purine nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
BP	GO:0043624	cellular protein complex disassembly	IEP	Predicted GO
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:0045454	cell redox homeostasis	IEP	Predicted GO
BP	GO:0046036	CTP metabolic process	IEP	Predicted GO
BP	GO:0046039	GTP metabolic process	IEP	Predicted GO
BP	GO:0046051	UTP metabolic process	IEP	Predicted GO
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0046129	purine ribonucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046700	heterocycle catabolic process	IEP	Predicted GO
BP	GO:0046939	nucleotide phosphorylation	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR019831	Mn/Fe_SOD_N	73	152
IPR019832	Mn/Fe_SOD_C	160	259

External Links

PlasmoDB	2270.t00122
PlasmoDB	3885871
PlasmoDB	MAL6P1.194
PlasmoDB	PFF1130c

PF3D7_0623500 (SOD2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation