PF3D7_0826100 (HEUL)

Aliases : HEUL

Description : SSF56204: "HECT, E3 ligase catalytic domain". Pfam domain(s): PF00632: HECT-domain (ubiquitin-transferase).

Gene families : OG_01_0000058 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000058_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0826100
Cluster	P. falciparum: Cluster_8

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0704500	HEUL	SSF56204: HECT, E3 ligase catalytic domain. Pfam...	0.13	Orthofinderv1.1.8
PBANKA_0928700	No alias	SSF56204: HECT, E3 ligase catalytic domain. Pfam...	0.02	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	ISS	PlasmoDB
MF	GO:0004842	ubiquitin-protein transferase activity	IEA	Interproscan predictions
MF	GO:0004842	ubiquitin-protein transferase activity	IEA	PlasmoDB
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006511	ubiquitin-dependent protein catabolic process	ISS	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009405	pathogenesis	ISO	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016049	cell growth	ISO	PlasmoDB
MF	GO:0016740	transferase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0019941	modification-dependent protein catabolic process	None	Extended
BP	GO:0040007	growth	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043632	modification-dependent macromolecule catabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
CC	GO:0000177	cytoplasmic exosome (RNase complex)	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006607	NLS-bearing protein import into nucleus	IEP	Predicted GO
BP	GO:0006896	Golgi to vacuole transport	IEP	Predicted GO
BP	GO:0006913	nucleocytoplasmic transport	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008270	zinc ion binding	IEP	Predicted GO
BP	GO:0009790	embryo development	IEP	Predicted GO
BP	GO:0009913	epidermal cell differentiation	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0030216	keratinocyte differentiation	IEP	Predicted GO
BP	GO:0030855	epithelial cell differentiation	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
BP	GO:0032012	regulation of ARF protein signal transduction	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0045095	keratin filament	IEP	Predicted GO
BP	GO:0046578	regulation of Ras protein signal transduction	IEP	Predicted GO
BP	GO:0051056	regulation of small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0051169	nuclear transport	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
BP	GO:1902531	regulation of intracellular signal transduction	IEP	Predicted GO
BP	GO:1902626	assembly of large subunit precursor of preribosome	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000569	HECT_dom	8286	8590

External Links

PlasmoDB	2655229
PlasmoDB	MAL8P1.23

PF3D7_0826100 (HEUL)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation