PF3D7_0900100 (VAR)

Aliases : VAR

Description : SSF140924: No description available. Pfam domain(s): PF15447: N-terminal segments of PfEMP1, PF05424: Duffy binding domain, PF18562: Cysteine-Rich Interdomain Region 1 gamma, PF03011: PFEMP DBL domain, PF15445: "acidic terminal segments, variant surface antigen of PfEMP1".

Gene families : OG_01_0000012 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000012_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0900100
Cluster	P. falciparum: Cluster_19

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009405	pathogenesis	IEA	Interproscan predictions
BP	GO:0009405	pathogenesis	IEA	PlasmoDB
CC	GO:0016021	integral component of membrane	IEA	Interproscan predictions
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
CC	GO:0020002	host cell plasma membrane	TAS	PlasmoDB
CC	GO:0020030	infected host cell surface knob	TAS	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033644	host cell membrane	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
CC	GO:0044217	other organism part	None	Extended
CC	GO:0044218	other organism cell membrane	None	Extended
CC	GO:0044279	other organism membrane	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044425	membrane part	None	Extended
MF	GO:0046789	host cell surface receptor binding	IEA	Interproscan predictions
MF	GO:0046789	host cell surface receptor binding	IEA	PlasmoDB
MF	GO:0046812	host cell surface binding	None	Extended
MF	GO:0050839	cell adhesion molecule binding	TAS	PlasmoDB
BP	GO:0051704	multi-organism process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
CC	GO:0020009	microneme	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004258	DBL	644	797
IPR004258	DBL	1532	1674
IPR029211	PfEMP1_ATS	1800	2270
IPR029210	PfEMP1_NTS	15	49
IPR008602	Duffy-antigen_binding	117	268
IPR008602	Duffy-antigen_binding	951	1201

External Links

PlasmoDB	813289
PlasmoDB	PFI0005w

PF3D7_0900100 (VAR)

Expression Profile

Co-expression Networks

Functional Annotation