PF3D7_0905300

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF17857: AAA+ lid domain, PF12777: Microtubule-binding stalk of dynein motor, PF08393: "Dynein heavy chain, N-terminal region 2", PF12780: P-loop containing dynein motor region D4, PF12774: Hydrolytic ATP binding site of dynein motor region, PF03028: Dynein heavy chain region D6 P-loop domain, PF12781: ATP-binding dynein motor region, PF18199: Dynein heavy chain C-terminal domain, PF18198: Dynein heavy chain AAA lid domain, PF12775: P-loop containing dynein motor region.

Gene families : OG_01_0000020 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000020_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0905300
Cluster	P. falciparum: Cluster_15

Target	Alias	Description	ECC score	Gene Family Method
PBANKA_0416100	MG1	SSF52540: P-loop containing nucleoside triphosphate...	0.11	Orthofinderv1.1.8
PBANKA_0507300	No alias	SSF52540: P-loop containing nucleoside triphosphate...	0.1	Orthofinderv1.1.8
PBANKA_0925400	No alias	SSF117281: Kelch-type beta propeller, SSF52540: P-loop...	0.08	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003774	motor activity	None	Extended
MF	GO:0003777	microtubule motor activity	IEA	Interproscan predictions
MF	GO:0003777	microtubule motor activity	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005875	microtubule associated complex	None	Extended
BP	GO:0006928	movement of cell or subcellular component	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007018	microtubule-based movement	IEA	Interproscan predictions
BP	GO:0007018	microtubule-based movement	IEA	PlasmoDB
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0030286	dynein complex	IEA	Interproscan predictions
CC	GO:0030286	dynein complex	IEA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044430	cytoskeletal part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1902494	catalytic complex	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003690	double-stranded DNA binding	IEP	Predicted GO
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Predicted GO
MF	GO:0004012	phospholipid-translocating ATPase activity	IEP	Predicted GO
MF	GO:0004523	RNA-DNA hybrid ribonuclease activity	IEP	Predicted GO
MF	GO:0004550	nucleoside diphosphate kinase activity	IEP	Predicted GO
MF	GO:0004655	porphobilinogen synthase activity	IEP	Predicted GO
MF	GO:0004708	MAP kinase kinase activity	IEP	Predicted GO
MF	GO:0004712	protein serine/threonine/tyrosine kinase activity	IEP	Predicted GO
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005102	signaling receptor binding	IEP	Predicted GO
MF	GO:0005544	calcium-dependent phospholipid binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005874	microtubule	IEP	Predicted GO
CC	GO:0005929	cilium	IEP	Predicted GO
CC	GO:0005930	axoneme	IEP	Predicted GO
BP	GO:0006183	GTP biosynthetic process	IEP	Predicted GO
BP	GO:0006228	UTP biosynthetic process	IEP	Predicted GO
BP	GO:0006241	CTP biosynthetic process	IEP	Predicted GO
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0007219	Notch signaling pathway	IEP	Predicted GO
MF	GO:0008017	microtubule binding	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008097	5S rRNA binding	IEP	Predicted GO
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
CC	GO:0031514	motile cilium	IEP	Predicted GO
CC	GO:0032299	ribonuclease H2 complex	IEP	Predicted GO
BP	GO:0044007	dissemination or transmission of symbiont from host	IEP	Predicted GO
CC	GO:0044441	ciliary part	IEP	Predicted GO
CC	GO:0044463	cell projection part	IEP	Predicted GO
BP	GO:0046036	CTP metabolic process	IEP	Predicted GO
BP	GO:0046039	GTP metabolic process	IEP	Predicted GO
BP	GO:0046051	UTP metabolic process	IEP	Predicted GO
BP	GO:0046777	protein autophosphorylation	IEP	Predicted GO
MF	GO:0051010	microtubule plus-end binding	IEP	Predicted GO
BP	GO:0051821	dissemination or transmission of organism from other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	IEP	Predicted GO
CC	GO:0099080	supramolecular complex	IEP	Predicted GO
CC	GO:0099081	supramolecular polymer	IEP	Predicted GO
CC	GO:0099512	supramolecular fiber	IEP	Predicted GO
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	Predicted GO
CC	GO:0120025	plasma membrane bounded cell projection	IEP	Predicted GO
CC	GO:0120038	plasma membrane bounded cell projection part	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004273	Dynein_heavy_D6_P-loop	5401	5517
IPR024743	Dynein_HC_stalk	4373	4731
IPR013602	Dynein_heavy_dom-2	1963	2067
IPR013602	Dynein_heavy_dom-2	2263	2563
IPR035699	AAA_6	2707	3038
IPR024317	Dynein_heavy_chain_D4_dom	4218	4359
IPR024317	Dynein_heavy_chain_D4_dom	4025	4164
IPR035706	AAA_9	4760	4983

External Links

PlasmoDB	813332
PlasmoDB	PFI0260c

PF3D7_0905300

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation