PF3D7_0917600 (PRP43)


Aliases : PRP43

Description : SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF07717: Oligonucleotide/oligosaccharide-binding (OB)-fold, PF00271: Helicase conserved C-terminal domain, PF04408: Helicase associated domain (HA2), PF00270: DEAD/DEAH box helicase.


Gene families : OG_01_0000023 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000023_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0917600
Cluster P. falciparum: Cluster_34

Target Alias Description ECC score Gene Family Method Actions
PBANKA_0514100 PRP22 SSF50249: Nucleic acid-binding, OB-fold, SSF52540:... 0.02 Orthofinderv1.1.8
PBANKA_0818600 PRP43 SSF52540: P-loop containing nucleoside triphosphate... 0.04 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0003676 nucleic acid binding IEA Interproscan predictions
MF GO:0003676 nucleic acid binding IEA PlasmoDB
MF GO:0004386 helicase activity IEA Interproscan predictions
MF GO:0004386 helicase activity IEA PlasmoDB
MF GO:0005524 ATP binding IEA Interproscan predictions
MF GO:0005524 ATP binding IEA PlasmoDB
Type GO Term Name Evidence Source
BP GO:0000027 ribosomal large subunit assembly IEP Predicted GO
CC GO:0000127 transcription factor TFIIIC complex IEP Predicted GO
MF GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
CC GO:0000408 EKC/KEOPS complex IEP Predicted GO
CC GO:0000428 DNA-directed RNA polymerase complex IEP Predicted GO
CC GO:0002189 ribose phosphate diphosphokinase complex IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003724 RNA helicase activity IEP Predicted GO
MF GO:0003727 single-stranded RNA binding IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0003921 GMP synthase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0003963 RNA-3'-phosphate cyclase activity IEP Predicted GO
MF GO:0004004 ATP-dependent RNA helicase activity IEP Predicted GO
MF GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity IEP Predicted GO
MF GO:0004356 glutamate-ammonia ligase activity IEP Predicted GO
MF GO:0004551 nucleotide diphosphatase activity IEP Predicted GO
MF GO:0004749 ribose phosphate diphosphokinase activity IEP Predicted GO
MF GO:0004802 transketolase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004818 glutamate-tRNA ligase activity IEP Predicted GO
MF GO:0004824 lysine-tRNA ligase activity IEP Predicted GO
MF GO:0004832 valine-tRNA ligase activity IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005654 nucleoplasm IEP Predicted GO
CC GO:0005666 RNA polymerase III complex IEP Predicted GO
CC GO:0005667 transcription factor complex IEP Predicted GO
CC GO:0005681 spliceosomal complex IEP Predicted GO
CC GO:0005686 U2 snRNP IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005732 small nucleolar ribonucleoprotein complex IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
BP GO:0006002 fructose 6-phosphate metabolic process IEP Predicted GO
BP GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006164 purine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006360 transcription by RNA polymerase I IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006366 transcription by RNA polymerase II IEP Predicted GO
BP GO:0006383 transcription by RNA polymerase III IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006397 mRNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006424 glutamyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006430 lysyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006438 valyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006541 glutamine metabolic process IEP Predicted GO
BP GO:0006542 glutamine biosynthetic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0007050 cell cycle arrest IEP Predicted GO
MF GO:0008026 ATP-dependent helicase activity IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008186 RNA-dependent ATPase activity IEP Predicted GO
MF GO:0008187 poly-pyrimidine tract binding IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008238 exopeptidase activity IEP Predicted GO
BP GO:0008283 cell proliferation IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
MF GO:0008452 RNA ligase activity IEP Predicted GO
MF GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009165 nucleotide biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010501 RNA secondary structure unwinding IEP Predicted GO
BP GO:0015959 diadenosine polyphosphate metabolic process IEP Predicted GO
BP GO:0015960 diadenosine polyphosphate biosynthetic process IEP Predicted GO
BP GO:0015965 diadenosine tetraphosphate metabolic process IEP Predicted GO
BP GO:0015966 diadenosine tetraphosphate biosynthetic process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016071 mRNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016211 ammonia ligase activity IEP Predicted GO
CC GO:0016281 eukaryotic translation initiation factor 4F complex IEP Predicted GO
MF GO:0016433 rRNA (adenine) methyltransferase activity IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016744 transferase activity, transferring aldehyde or ketonic groups IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0016880 acid-ammonia (or amide) ligase activity IEP Predicted GO
MF GO:0016886 ligase activity, forming phosphoric ester bonds IEP Predicted GO
MF GO:0017069 snRNA binding IEP Predicted GO
MF GO:0017150 tRNA dihydrouridine synthase activity IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
BP GO:0022618 ribonucleoprotein complex assembly IEP Predicted GO
MF GO:0030515 snoRNA binding IEP Predicted GO
MF GO:0030621 U4 snRNA binding IEP Predicted GO
MF GO:0030623 U5 snRNA binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
CC GO:0030686 90S preribosome IEP Predicted GO
CC GO:0030687 preribosome, large subunit precursor IEP Predicted GO
CC GO:0030880 RNA polymerase complex IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
CC GO:0031428 box C/D snoRNP complex IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033677 DNA/RNA helicase activity IEP Predicted GO
MF GO:0033679 3'-5' DNA/RNA helicase activity IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
CC GO:0034457 Mpp10 complex IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
MF GO:0034511 U3 snoRNA binding IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0042255 ribosome assembly IEP Predicted GO
BP GO:0042256 mature ribosome assembly IEP Predicted GO
BP GO:0042273 ribosomal large subunit biogenesis IEP Predicted GO
MF GO:0043023 ribosomal large subunit binding IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043484 regulation of RNA splicing IEP Predicted GO
BP GO:0043933 protein-containing complex subunit organization IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044452 nucleolar part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
CC GO:0044798 nuclear transcription factor complex IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046391 5-phosphoribose 1-diphosphate metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
MF GO:0047334 diphosphate-fructose-6-phosphate 1-phosphotransferase activity IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
CC GO:0055029 nuclear DNA-directed RNA polymerase complex IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
BP GO:0065003 protein-containing complex assembly IEP Predicted GO
MF GO:0070035 purine NTP-dependent helicase activity IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071826 ribonucleoprotein complex subunit organization IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072522 purine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090407 organophosphate biosynthetic process IEP Predicted GO
CC GO:0090576 RNA polymerase III transcription factor complex IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
CC GO:1990234 transferase complex IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR011709 DUF1605 720 796
IPR001650 Helicase_C 365 502
IPR011545 DEAD/DEAH_box_helicase_dom 177 329
IPR007502 Helicase-assoc_dom 565 653
PlasmoDB 813452
PlasmoDB PFI0860c