PF3D7_0932200 (PFN)

Aliases : PFN

Description : SSF55770: Profilin superfamily. Pfam domain(s): PF00235: Profilin.

Gene families : OG_01_0001036 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001036_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0932200
Cluster	P. falciparum: Cluster_42

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0833000	PFN	SSF55770: Profilin superfamily. Pfam domain(s): PF00235:...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003779	actin binding	ISO	PlasmoDB
MF	GO:0003779	actin binding	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005543	phospholipid binding	IDA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISO	PlasmoDB
CC	GO:0005737	cytoplasm	IDA	PlasmoDB
CC	GO:0005829	cytosol	IDA	PlasmoDB
BP	GO:0006928	movement of cell or subcellular component	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007010	cytoskeleton organization	None	Extended
BP	GO:0008064	regulation of actin polymerization or depolymerization	None	Extended
MF	GO:0008092	cytoskeletal protein binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008289	lipid binding	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010639	negative regulation of organelle organization	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0030029	actin filament-based process	None	Extended
BP	GO:0030036	actin cytoskeleton organization	IEA	PlasmoDB
BP	GO:0030260	entry into host cell	ISO	PlasmoDB
BP	GO:0030832	regulation of actin filament length	None	Extended
BP	GO:0030833	regulation of actin filament polymerization	None	Extended
BP	GO:0030837	negative regulation of actin filament polymerization	None	Extended
BP	GO:0031333	negative regulation of protein complex assembly	None	Extended
BP	GO:0032271	regulation of protein polymerization	None	Extended
BP	GO:0032272	negative regulation of protein polymerization	None	Extended
BP	GO:0032507	maintenance of protein location in cell	None	Extended
BP	GO:0032535	regulation of cellular component size	None	Extended
BP	GO:0032956	regulation of actin cytoskeleton organization	None	Extended
BP	GO:0032970	regulation of actin filament-based process	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0040011	locomotion	None	Extended
BP	GO:0042989	sequestering of actin monomers	IDA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043254	regulation of protein complex assembly	None	Extended
BP	GO:0044087	regulation of cellular component biogenesis	None	Extended
BP	GO:0044409	entry into host	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045185	maintenance of protein location	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0048870	cell motility	ISO	PlasmoDB
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051129	negative regulation of cellular component organization	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051235	maintenance of location	None	Extended
BP	GO:0051493	regulation of cytoskeleton organization	None	Extended
BP	GO:0051494	negative regulation of cytoskeleton organization	None	Extended
BP	GO:0051651	maintenance of location in cell	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051828	entry into other organism involved in symbiotic interaction	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
MF	GO:0070064	proline-rich region binding	IDA	PlasmoDB
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090066	regulation of anatomical structure size	None	Extended
BP	GO:0110053	regulation of actin filament organization	None	Extended
BP	GO:1902903	regulation of supramolecular fiber organization	None	Extended
BP	GO:1902904	negative regulation of supramolecular fiber organization	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000786	nucleosome	IEP	Predicted GO
CC	GO:0000808	origin recognition complex	IEP	Predicted GO
BP	GO:0001932	regulation of protein phosphorylation	IEP	Predicted GO
BP	GO:0002377	immunoglobulin production	IEP	Predicted GO
BP	GO:0002440	production of molecular mediator of immune response	IEP	Predicted GO
MF	GO:0003785	actin monomer binding	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003826	alpha-ketoacid dehydrogenase activity	IEP	Predicted GO
MF	GO:0004103	choline kinase activity	IEP	Predicted GO
MF	GO:0004633	phosphopantothenoylcysteine decarboxylase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0004690	cyclic nucleotide-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004692	cGMP-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004722	protein serine/threonine phosphatase activity	IEP	Predicted GO
MF	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	IEP	Predicted GO
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Predicted GO
CC	GO:0005884	actin filament	IEP	Predicted GO
CC	GO:0005886	plasma membrane	IEP	Predicted GO
CC	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex	IEP	Predicted GO
CC	GO:0005952	cAMP-dependent protein kinase complex	IEP	Predicted GO
CC	GO:0005955	calcineurin complex	IEP	Predicted GO
BP	GO:0006333	chromatin assembly or disassembly	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006465	signal peptide processing	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006656	phosphatidylcholine biosynthetic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Predicted GO
MF	GO:0008603	cAMP-dependent protein kinase regulator activity	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016831	carboxy-lyase activity	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019220	regulation of phosphate metabolic process	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
BP	GO:0030048	actin filament-based movement	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
BP	GO:0030154	cell differentiation	IEP	Predicted GO
BP	GO:0031399	regulation of protein modification process	IEP	Predicted GO
CC	GO:0031941	filamentous actin	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0032502	developmental process	IEP	Predicted GO
MF	GO:0033265	choline binding	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
MF	GO:0042165	neurotransmitter binding	IEP	Predicted GO
BP	GO:0042325	regulation of phosphorylation	IEP	Predicted GO
CC	GO:0042643	actomyosin, actin portion	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
MF	GO:0043495	protein membrane anchor	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044267	cellular protein metabolic process	IEP	Predicted GO
CC	GO:0044427	chromosomal part	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	IEP	Predicted GO
BP	GO:0046470	phosphatidylcholine metabolic process	IEP	Predicted GO
BP	GO:0048869	cellular developmental process	IEP	Predicted GO
BP	GO:0051014	actin filament severing	IEP	Predicted GO
BP	GO:0051174	regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO
BP	GO:0060327	cytoplasmic actin-based contraction involved in cell motility	IEP	Predicted GO
BP	GO:0070252	actin-mediated cell contraction	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070405	ammonium ion binding	IEP	Predicted GO
BP	GO:0097164	ammonium ion metabolic process	IEP	Predicted GO
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
CC	GO:1903293	phosphatase complex	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005455	PFN	6	169

External Links

PlasmoDB	813593
PlasmoDB	PFI1565w

PF3D7_0932200 (PFN)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation