PF3D7_1009000 (DPH5)

Aliases : DPH5

Description : SSF53790: Tetrapyrrole methylase superfamily. Pfam domain(s): PF00590: Tetrapyrrole (Corrin/Porphyrin) Methylases.

Gene families : OG_01_0001582 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001582_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1009000
Cluster	P. falciparum: Cluster_38

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1207300	DPH5	SSF53790: Tetrapyrrole methylase superfamily. Pfam...	0.05	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004164	diphthine synthase activity	ISS	PlasmoDB
MF	GO:0004164	diphthine synthase activity	IEA	PlasmoDB
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006448	regulation of translational elongation	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	IEA	PlasmoDB
MF	GO:0008168	methyltransferase activity	IEA	Interproscan predictions
MF	GO:0008168	methyltransferase activity	IEA	PlasmoDB
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0017182	peptidyl-diphthamide metabolic process	None	Extended
BP	GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	ISS	PlasmoDB
BP	GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	IEA	PlasmoDB
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018202	peptidyl-histidine modification	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:1900247	regulation of cytoplasmic translational elongation	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2000765	regulation of cytoplasmic translation	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000027	ribosomal large subunit assembly	IEP	Predicted GO
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
MF	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	IEP	Predicted GO
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	IEP	Predicted GO
CC	GO:0000408	EKC/KEOPS complex	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0002181	cytoplasmic translation	IEP	Predicted GO
CC	GO:0002189	ribose phosphate diphosphokinase complex	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003735	structural constituent of ribosome	IEP	Predicted GO
MF	GO:0003746	translation elongation factor activity	IEP	Predicted GO
MF	GO:0003921	GMP synthase activity	IEP	Predicted GO
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0003963	RNA-3'-phosphate cyclase activity	IEP	Predicted GO
MF	GO:0004152	dihydroorotate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004364	glutathione transferase activity	IEP	Predicted GO
MF	GO:0004588	orotate phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004590	orotidine-5'-phosphate decarboxylase activity	IEP	Predicted GO
MF	GO:0004735	pyrroline-5-carboxylate reductase activity	IEP	Predicted GO
MF	GO:0004749	ribose phosphate diphosphokinase activity	IEP	Predicted GO
MF	GO:0004815	aspartate-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005198	structural molecule activity	IEP	Predicted GO
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005347	ATP transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005471	ATP:ADP antiporter activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005622	intracellular	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
CC	GO:0005743	mitochondrial inner membrane	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005840	ribosome	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
CC	GO:0005853	eukaryotic translation elongation factor 1 complex	IEP	Predicted GO
CC	GO:0005854	nascent polypeptide-associated complex	IEP	Predicted GO
BP	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006177	GMP biosynthetic process	IEP	Predicted GO
BP	GO:0006206	pyrimidine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006412	translation	IEP	Predicted GO
BP	GO:0006414	translational elongation	IEP	Predicted GO
BP	GO:0006422	aspartyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006458	'de novo' protein folding	IEP	Predicted GO
BP	GO:0006518	peptide metabolic process	IEP	Predicted GO
BP	GO:0006560	proline metabolic process	IEP	Predicted GO
BP	GO:0006561	proline biosynthetic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006863	purine nucleobase transport	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008479	queuine tRNA-ribosyltransferase activity	IEP	Predicted GO
MF	GO:0008649	rRNA methyltransferase activity	IEP	Predicted GO
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009116	nucleoside metabolic process	IEP	Predicted GO
BP	GO:0009304	tRNA transcription	IEP	Predicted GO
MF	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0015215	nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015216	purine nucleotide transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015217	ADP transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015851	nucleobase transport	IEP	Predicted GO
BP	GO:0015858	nucleoside transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Predicted GO
CC	GO:0015934	large ribosomal subunit	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
BP	GO:0016075	rRNA catabolic process	IEP	Predicted GO
CC	GO:0016324	apical plasma membrane	IEP	Predicted GO
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016433	rRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016434	rRNA (cytosine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Predicted GO
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	IEP	Predicted GO
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019856	pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
CC	GO:0019866	organelle inner membrane	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predicted GO
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030686	90S preribosome	IEP	Predicted GO
CC	GO:0030687	preribosome, large subunit precursor	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
BP	GO:0032238	adenosine transport	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
BP	GO:0034661	ncRNA catabolic process	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042255	ribosome assembly	IEP	Predicted GO
BP	GO:0042273	ribosomal large subunit biogenesis	IEP	Predicted GO
BP	GO:0042274	ribosomal small subunit biogenesis	IEP	Predicted GO
MF	GO:0042781	3'-tRNA processing endoribonuclease activity	IEP	Predicted GO
BP	GO:0042797	tRNA transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0043043	peptide biosynthetic process	IEP	Predicted GO
MF	GO:0043139	5'-3' DNA helicase activity	IEP	Predicted GO
MF	GO:0043141	ATP-dependent 5'-3' DNA helicase activity	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0043603	cellular amide metabolic process	IEP	Predicted GO
BP	GO:0043604	amide biosynthetic process	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0046037	GMP metabolic process	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0046391	5-phosphoribose 1-diphosphate metabolic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051083	'de novo' cotranslational protein folding	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
MF	GO:0070037	rRNA (pseudouridine) methyltransferase activity	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
CC	GO:0098590	plasma membrane region	IEP	Predicted GO
BP	GO:0098781	ncRNA transcription	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901657	glycosyl compound metabolic process	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000878	4pyrrol_Mease	3	178

External Links

PlasmoDB	810245
PlasmoDB	PF10_0087

PF3D7_1009000 (DPH5)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation