PF3D7_1015300 (METAP1b)


Aliases : METAP1b

Description : SSF55920: Creatinase/aminopeptidase-like. Pfam domain(s): PF00557: Metallopeptidase family M24, PF15801: "zf-MYND-like zinc finger, mRNA-binding".


Gene families : OG_01_0001613 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001613_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1015300
Cluster P. falciparum: Cluster_38


Type GO Term Name Evidence Source
MF GO:0004177 aminopeptidase activity IEA PlasmoDB
BP GO:0006508 proteolysis ISM PlasmoDB
BP GO:0006508 proteolysis IEA PlasmoDB
MF GO:0008235 metalloexopeptidase activity ISS PlasmoDB
MF GO:0008235 metalloexopeptidase activity IEA PlasmoDB
Type GO Term Name Evidence Source
BP GO:0000027 ribosomal large subunit assembly IEP Predicted GO
BP GO:0000054 ribosomal subunit export from nucleus IEP Predicted GO
BP GO:0000055 ribosomal large subunit export from nucleus IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity IEP Predicted GO
CC GO:0000428 DNA-directed RNA polymerase complex IEP Predicted GO
BP GO:0001510 RNA methylation IEP Predicted GO
MF GO:0002161 aminoacyl-tRNA editing activity IEP Predicted GO
BP GO:0002181 cytoplasmic translation IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003848 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity IEP Predicted GO
MF GO:0003883 CTP synthase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0003921 GMP synthase activity IEP Predicted GO
MF GO:0003922 GMP synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0003963 RNA-3'-phosphate cyclase activity IEP Predicted GO
MF GO:0004152 dihydroorotate dehydrogenase activity IEP Predicted GO
MF GO:0004156 dihydropteroate synthase activity IEP Predicted GO
MF GO:0004164 diphthine synthase activity IEP Predicted GO
MF GO:0004347 glucose-6-phosphate isomerase activity IEP Predicted GO
MF GO:0004364 glutathione transferase activity IEP Predicted GO
MF GO:0004588 orotate phosphoribosyltransferase activity IEP Predicted GO
MF GO:0004802 transketolase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0004815 aspartate-tRNA ligase activity IEP Predicted GO
MF GO:0004820 glycine-tRNA ligase activity IEP Predicted GO
MF GO:0004822 isoleucine-tRNA ligase activity IEP Predicted GO
MF GO:0004829 threonine-tRNA ligase activity IEP Predicted GO
MF GO:0004832 valine-tRNA ligase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005654 nucleoplasm IEP Predicted GO
CC GO:0005666 RNA polymerase III complex IEP Predicted GO
CC GO:0005730 nucleolus IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006177 GMP biosynthetic process IEP Predicted GO
BP GO:0006241 CTP biosynthetic process IEP Predicted GO
BP GO:0006360 transcription by RNA polymerase I IEP Predicted GO
BP GO:0006364 rRNA processing IEP Predicted GO
BP GO:0006383 transcription by RNA polymerase III IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006399 tRNA metabolic process IEP Predicted GO
BP GO:0006400 tRNA modification IEP Predicted GO
BP GO:0006405 RNA export from nucleus IEP Predicted GO
BP GO:0006409 tRNA export from nucleus IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006422 aspartyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006426 glycyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006428 isoleucyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006435 threonyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006438 valyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006520 cellular amino acid metabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006753 nucleoside phosphate metabolic process IEP Predicted GO
BP GO:0006761 dihydrofolate biosynthetic process IEP Predicted GO
BP GO:0006863 purine nucleobase transport IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0008033 tRNA processing IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008168 methyltransferase activity IEP Predicted GO
MF GO:0008173 RNA methyltransferase activity IEP Predicted GO
MF GO:0008175 tRNA methyltransferase activity IEP Predicted GO
MF GO:0008176 tRNA (guanine-N7-)-methyltransferase activity IEP Predicted GO
MF GO:0008479 queuine tRNA-ribosyltransferase activity IEP Predicted GO
MF GO:0008649 rRNA methyltransferase activity IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009117 nucleotide metabolic process IEP Predicted GO
BP GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process IEP Predicted GO
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Predicted GO
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009260 ribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009304 tRNA transcription IEP Predicted GO
BP GO:0009451 RNA modification IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010501 RNA secondary structure unwinding IEP Predicted GO
MF GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEP Predicted GO
BP GO:0015851 nucleobase transport IEP Predicted GO
BP GO:0015858 nucleoside transport IEP Predicted GO
BP GO:0015931 nucleobase-containing compound transport IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016072 rRNA metabolic process IEP Predicted GO
MF GO:0016426 tRNA (adenine) methyltransferase activity IEP Predicted GO
MF GO:0016429 tRNA (adenine-N1-)-methyltransferase activity IEP Predicted GO
MF GO:0016433 rRNA (adenine) methyltransferase activity IEP Predicted GO
MF GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016741 transferase activity, transferring one-carbon groups IEP Predicted GO
MF GO:0016744 transferase activity, transferring aldehyde or ketonic groups IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups IEP Predicted GO
MF GO:0016874 ligase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
BP GO:0019693 ribose phosphate metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
BP GO:0022613 ribonucleoprotein complex biogenesis IEP Predicted GO
BP GO:0022618 ribonucleoprotein complex assembly IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
BP GO:0030488 tRNA methylation IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
CC GO:0030684 preribosome IEP Predicted GO
CC GO:0030686 90S preribosome IEP Predicted GO
CC GO:0030687 preribosome, large subunit precursor IEP Predicted GO
CC GO:0030688 preribosome, small subunit precursor IEP Predicted GO
CC GO:0030880 RNA polymerase complex IEP Predicted GO
MF GO:0031369 translation initiation factor binding IEP Predicted GO
BP GO:0031503 protein-containing complex localization IEP Predicted GO
CC GO:0031515 tRNA (m1A) methyltransferase complex IEP Predicted GO
CC GO:0032040 small-subunit processome IEP Predicted GO
BP GO:0032238 adenosine transport IEP Predicted GO
BP GO:0032259 methylation IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033750 ribosome localization IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
BP GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic IEP Predicted GO
BP GO:0034470 ncRNA processing IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Predicted GO
BP GO:0034660 ncRNA metabolic process IEP Predicted GO
CC GO:0034708 methyltransferase complex IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042254 ribosome biogenesis IEP Predicted GO
BP GO:0042274 ribosomal small subunit biogenesis IEP Predicted GO
BP GO:0042493 response to drug IEP Predicted GO
BP GO:0042779 tRNA 3'-trailer cleavage IEP Predicted GO
MF GO:0042781 3'-tRNA processing endoribonuclease activity IEP Predicted GO
BP GO:0042797 tRNA transcription by RNA polymerase III IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
CC GO:0043527 tRNA methyltransferase complex IEP Predicted GO
BP GO:0044085 cellular component biogenesis IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0046036 CTP metabolic process IEP Predicted GO
BP GO:0046037 GMP metabolic process IEP Predicted GO
BP GO:0046390 ribose phosphate biosynthetic process IEP Predicted GO
MF GO:0046403 polynucleotide 3'-phosphatase activity IEP Predicted GO
BP GO:0046452 dihydrofolate metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0050657 nucleic acid transport IEP Predicted GO
BP GO:0050658 RNA transport IEP Predicted GO
BP GO:0051031 tRNA transport IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051168 nuclear export IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051236 establishment of RNA localization IEP Predicted GO
BP GO:0051656 establishment of organelle localization IEP Predicted GO
MF GO:0052689 carboxylic ester hydrolase activity IEP Predicted GO
CC GO:0055029 nuclear DNA-directed RNA polymerase complex IEP Predicted GO
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Predicted GO
CC GO:0061695 transferase complex, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0070037 rRNA (pseudouridine) methyltransferase activity IEP Predicted GO
BP GO:0071426 ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus IEP Predicted GO
BP GO:0071826 ribonucleoprotein complex subunit organization IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEP Predicted GO
BP GO:0097064 ncRNA export from nucleus IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
MF GO:0098518 polynucleotide phosphatase activity IEP Predicted GO
BP GO:0098781 ncRNA transcription IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
MF GO:0140101 catalytic activity, acting on a tRNA IEP Predicted GO
MF GO:0140102 catalytic activity, acting on a rRNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901070 guanosine-containing compound biosynthetic process IEP Predicted GO
BP GO:1901135 carbohydrate derivative metabolic process IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901566 organonitrogen compound biosynthetic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1905267 endonucleolytic cleavage involved in tRNA processing IEP Predicted GO
CC GO:1990234 transferase complex IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR000994 Pept_M24 260 489
IPR031615 Zfn-C6H2 118 160
PlasmoDB 810308
PlasmoDB PF10_0150