PF3D7_1125400 (TIM44)

Aliases : TIM44

Description : SSF54427: NTF2-like domain superfamily. Pfam domain(s): PF04280: Tim44-like domain.

Gene families : OG_01_0002698 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002698_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1125400
Cluster	P. falciparum: Cluster_38

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	ISS	PlasmoDB
CC	GO:0005743	mitochondrial inner membrane	ISS	PlasmoDB
BP	GO:0006605	protein targeting	None	Extended
BP	GO:0006626	protein targeting to mitochondrion	ISS	PlasmoDB
BP	GO:0006810	transport	None	Extended
BP	GO:0006839	mitochondrial transport	None	Extended
BP	GO:0006886	intracellular protein transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008320	protein transmembrane transporter activity	None	Extended
MF	GO:0008565	protein transporter activity	None	Extended
BP	GO:0015031	protein transport	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	ISS	PlasmoDB
BP	GO:0015833	peptide transport	None	Extended
CC	GO:0016020	membrane	None	Extended
CC	GO:0019866	organelle inner membrane	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022884	macromolecule transmembrane transporter activity	None	Extended
CC	GO:0031090	organelle membrane	None	Extended
CC	GO:0031966	mitochondrial membrane	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0033365	protein localization to organelle	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0042887	amide transmembrane transporter activity	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044429	mitochondrial part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0070585	protein localization to mitochondrion	None	Extended
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
BP	GO:0072594	establishment of protein localization to organelle	None	Extended
BP	GO:0072655	establishment of protein localization to mitochondrion	None	Extended
MF	GO:1904680	peptide transmembrane transporter activity	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
BP	GO:0000302	response to reactive oxygen species	IEP	Predicted GO
BP	GO:0000304	response to singlet oxygen	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
MF	GO:0000774	adenyl-nucleotide exchange factor activity	IEP	Predicted GO
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003824	catalytic activity	IEP	Predicted GO
MF	GO:0003883	CTP synthase activity	IEP	Predicted GO
MF	GO:0004019	adenylosuccinate synthase activity	IEP	Predicted GO
MF	GO:0004152	dihydroorotate dehydrogenase activity	IEP	Predicted GO
MF	GO:0004164	diphthine synthase activity	IEP	Predicted GO
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004359	glutaminase activity	IEP	Predicted GO
MF	GO:0004364	glutathione transferase activity	IEP	Predicted GO
MF	GO:0004588	orotate phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004735	pyrroline-5-carboxylate reductase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004815	aspartate-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004822	isoleucine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
CC	GO:0005854	nascent polypeptide-associated complex	IEP	Predicted GO
BP	GO:0006081	cellular aldehyde metabolic process	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006167	AMP biosynthetic process	IEP	Predicted GO
BP	GO:0006241	CTP biosynthetic process	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006422	aspartyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006428	isoleucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006560	proline metabolic process	IEP	Predicted GO
BP	GO:0006561	proline biosynthetic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0006807	nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0006863	purine nucleobase transport	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
BP	GO:0008152	metabolic process	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0008479	queuine tRNA-ribosyltransferase activity	IEP	Predicted GO
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEP	Predicted GO
BP	GO:0008614	pyridoxine metabolic process	IEP	Predicted GO
BP	GO:0008615	pyridoxine biosynthetic process	IEP	Predicted GO
MF	GO:0008649	rRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0009058	biosynthetic process	IEP	Predicted GO
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009266	response to temperature stimulus	IEP	Predicted GO
BP	GO:0009304	tRNA transcription	IEP	Predicted GO
MF	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0009408	response to heat	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
BP	GO:0009987	cellular process	IEP	Predicted GO
BP	GO:0015851	nucleobase transport	IEP	Predicted GO
BP	GO:0015858	nucleoside transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
CC	GO:0015935	small ribosomal subunit	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016434	rRNA (cytosine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	IEP	Predicted GO
MF	GO:0016740	transferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0030150	protein import into mitochondrial matrix	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
MF	GO:0030544	Hsp70 protein binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030687	preribosome, large subunit precursor	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
MF	GO:0031072	heat shock protein binding	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
BP	GO:0032238	adenosine transport	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
MF	GO:0034038	deoxyhypusine synthase activity	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
CC	GO:0034708	methyltransferase complex	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042273	ribosomal large subunit biogenesis	IEP	Predicted GO
BP	GO:0042274	ribosomal small subunit biogenesis	IEP	Predicted GO
BP	GO:0042797	tRNA transcription by RNA polymerase III	IEP	Predicted GO
MF	GO:0042802	identical protein binding	IEP	Predicted GO
MF	GO:0042803	protein homodimerization activity	IEP	Predicted GO
BP	GO:0042822	pyridoxal phosphate metabolic process	IEP	Predicted GO
BP	GO:0042823	pyridoxal phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044237	cellular metabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044249	cellular biosynthetic process	IEP	Predicted GO
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
CC	GO:0044391	ribosomal subunit	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044445	cytosolic part	IEP	Predicted GO
BP	GO:0046033	AMP metabolic process	IEP	Predicted GO
BP	GO:0046036	CTP metabolic process	IEP	Predicted GO
BP	GO:0046184	aldehyde biosynthetic process	IEP	Predicted GO
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0046983	protein dimerization activity	IEP	Predicted GO
BP	GO:0050983	obsolete deoxyhypusine biosynthetic process from spermidine	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
MF	GO:0051087	chaperone binding	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
MF	GO:0051879	Hsp90 protein binding	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
MF	GO:0070037	rRNA (pseudouridine) methyltransferase activity	IEP	Predicted GO
CC	GO:0070545	PeBoW complex	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071704	organic substance metabolic process	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0098781	ncRNA transcription	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901576	organic substance biosynthetic process	IEP	Predicted GO
BP	GO:1901700	response to oxygen-containing compound	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR007379	Tim44-like_dom	312	448

External Links

PlasmoDB	810812
PlasmoDB	PF11_0265

PF3D7_1125400 (TIM44)

Expression Profile

Co-expression Networks

Functional Annotation