PF3D7_1223400

Description : SSF81665: "P-type ATPase, transmembrane domain superfamily", SSF56784: HAD-like superfamily, SSF81653: "P-type ATPase, A domain superfamily", SSF81660: "P-type ATPase, cytoplasmic domain N". Pfam domain(s): PF16209: Phospholipid-translocating ATPase N-terminal, PF16212: Phospholipid-translocating P-type ATPase C-terminal, PF13246: Cation transport ATPase (P-type), PF00122: E1-E2 ATPase.

Gene families : OG_01_0002154 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002154_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1223400
Cluster	P. falciparum: Cluster_28

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004012	phospholipid-translocating ATPase activity	ISS	PlasmoDB
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005319	lipid transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	ISS	PlasmoDB
MF	GO:0005548	phospholipid transporter activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006820	anion transport	None	Extended
BP	GO:0006869	lipid transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0015711	organic anion transport	None	Extended
BP	GO:0015748	organophosphate ester transport	None	Extended
BP	GO:0015914	phospholipid transport	None	Extended
BP	GO:0015917	aminophospholipid transport	ISS	PlasmoDB
CC	GO:0016021	integral component of membrane	ISM	PlasmoDB
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000469	cleavage involved in rRNA processing	IEP	Predicted GO
BP	GO:0002028	regulation of sodium ion transport	IEP	Predicted GO
MF	GO:0003702	obsolete RNA polymerase II transcription factor activity	IEP	Predicted GO
MF	GO:0003727	single-stranded RNA binding	IEP	Predicted GO
MF	GO:0003916	DNA topoisomerase activity	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004402	histone acetyltransferase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005516	calmodulin binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
BP	GO:0006265	DNA topological change	IEP	Predicted GO
BP	GO:0006475	internal protein amino acid acetylation	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
MF	GO:0008143	poly(A) binding	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
MF	GO:0010484	H3 histone acetyltransferase activity	IEP	Predicted GO
BP	GO:0010959	regulation of metal ion transport	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015078	proton transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
BP	GO:0016573	histone acetylation	IEP	Predicted GO
MF	GO:0017025	TBP-class protein binding	IEP	Predicted GO
BP	GO:0018393	internal peptidyl-lysine acetylation	IEP	Predicted GO
BP	GO:0018394	peptidyl-lysine acetylation	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
CC	GO:0030015	CCR4-NOT core complex	IEP	Predicted GO
MF	GO:0030276	clathrin binding	IEP	Predicted GO
BP	GO:0031204	posttranslational protein targeting to membrane, translocation	IEP	Predicted GO
CC	GO:0031207	Sec62/Sec63 complex	IEP	Predicted GO
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
MF	GO:0034212	peptide N-acetyltransferase activity	IEP	Predicted GO
CC	GO:0035770	ribonucleoprotein granule	IEP	Predicted GO
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
BP	GO:0043966	histone H3 acetylation	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055088	lipid homeostasis	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
MF	GO:0070717	poly-purine tract binding	IEP	Predicted GO
BP	GO:0070897	transcription preinitiation complex assembly	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR032630	P_typ_ATPase_c	1385	1612
IPR032631	P-type_ATPase_N	57	110

External Links

PlasmoDB	2277.t00225
PlasmoDB	811277
PlasmoDB	MAL12P1.225
PlasmoDB	PFL1125w

PF3D7_1223400

Expression Profile

Co-expression Networks

Functional Annotation