PF3D7_1239500 (GyrB)

Aliases : GyrB

Description : SSF56719: "DNA topoisomerase, type IIA-like domain superfamily", SSF55874: Histidine kinase/HSP90-like ATPase superfamily, SSF54211: Ribosomal protein S5 domain 2-type fold. Pfam domain(s): PF00986: "DNA gyrase B subunit, carboxyl terminus", PF02518: "Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase", PF00204: DNA gyrase B, PF01751: Toprim domain.

Gene families : OG_01_0002210 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002210_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1239500

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1454000	GyrB	SSF54211: Ribosomal protein S5 domain 2-type fold,...	0.01	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IDA	PlasmoDB
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	Interproscan predictions
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	ISS	PlasmoDB
BP	GO:0006265	DNA topological change	IEA	Interproscan predictions
BP	GO:0006265	DNA topological change	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0016887	ATPase activity	IDA	PlasmoDB
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046983	protein dimerization activity	IDA	PlasmoDB
BP	GO:0051276	chromosome organization	None	Extended
MF	GO:0061505	DNA topoisomerase II activity	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004519	endonuclease activity	IEP	Predicted GO
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004536	deoxyribonuclease activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002288	DNA_gyrase_B_C	937	997
IPR013506	Topo_IIA_bsu_dom2	465	637
IPR006171	TOPRIM_domain	667	823
IPR003594	HATPase_C	148	338

External Links

PlasmoDB	2277.t00383
PlasmoDB	811435
PlasmoDB	MAL12P1.381
PlasmoDB	PFL1915w

PF3D7_1239500 (GyrB)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation