PF3D7_1247800 (DPAP2)

Aliases : DPAP2

Description : SSF54001: Papain-like cysteine peptidase superfamily, SSF75001: "Cathepsin C, exclusion domain superfamily". Pfam domain(s): PF08773: Cathepsin C exclusion domain, PF00112: Papain family cysteine protease.

Gene families : OG_01_0000432 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000432_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1247800
Cluster	P. falciparum: Cluster_21

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1460700	DPAP2	SSF54001: Papain-like cysteine peptidase superfamily,...	0.19	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004177	aminopeptidase activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IDA	PlasmoDB
BP	GO:0006508	proteolysis	ISS	PlasmoDB
BP	GO:0006508	proteolysis	IEA	Interproscan predictions
BP	GO:0006508	proteolysis	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	IEA	Interproscan predictions
MF	GO:0008234	cysteine-type peptidase activity	IEA	PlasmoDB
MF	GO:0008238	exopeptidase activity	None	Extended
MF	GO:0008239	dipeptidyl-peptidase activity	ISS	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
BP	GO:0035890	exit from host	None	Extended
BP	GO:0035891	exit from host cell	IMP	PlasmoDB
BP	GO:0040011	locomotion	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044310	osmiophilic body	IDA	PlasmoDB
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0052126	movement in host environment	None	Extended
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0071944	cell periphery	IDA	PlasmoDB
CC	GO:0097708	intracellular vesicle	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000150	recombinase activity	IEP	Predicted GO
BP	GO:0000270	peptidoglycan metabolic process	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
BP	GO:0000902	cell morphogenesis	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0005044	scavenger receptor activity	IEP	Predicted GO
MF	GO:0005201	extracellular matrix structural constituent	IEP	Predicted GO
CC	GO:0005576	extracellular region	IEP	Predicted GO
CC	GO:0005581	collagen trimer	IEP	Predicted GO
CC	GO:0005868	cytoplasmic dynein complex	IEP	Predicted GO
CC	GO:0005892	acetylcholine-gated channel complex	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006004	fucose metabolic process	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006023	aminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006024	glycosaminoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0006817	phosphate ion transport	IEP	Predicted GO
BP	GO:0006820	anion transport	IEP	Predicted GO
BP	GO:0008360	regulation of cell shape	IEP	Predicted GO
MF	GO:0008446	GDP-mannose 4,6-dehydratase activity	IEP	Predicted GO
BP	GO:0008653	lipopolysaccharide metabolic process	IEP	Predicted GO
BP	GO:0009103	lipopolysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0009252	peptidoglycan biosynthetic process	IEP	Predicted GO
BP	GO:0009653	anatomical structure morphogenesis	IEP	Predicted GO
BP	GO:0015698	inorganic anion transport	IEP	Predicted GO
MF	GO:0019134	glucosamine-1-phosphate N-acetyltransferase activity	IEP	Predicted GO
BP	GO:0019236	response to pheromone	IEP	Predicted GO
BP	GO:0019673	GDP-mannose metabolic process	IEP	Predicted GO
CC	GO:0020025	subpellicular microtubule	IEP	Predicted GO
CC	GO:0020039	pellicle	IEP	Predicted GO
BP	GO:0022603	regulation of anatomical structure morphogenesis	IEP	Predicted GO
BP	GO:0022604	regulation of cell morphogenesis	IEP	Predicted GO
BP	GO:0030203	glycosaminoglycan metabolic process	IEP	Predicted GO
BP	GO:0031297	replication fork processing	IEP	Predicted GO
BP	GO:0032989	cellular component morphogenesis	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
CC	GO:0034702	ion channel complex	IEP	Predicted GO
MF	GO:0038024	cargo receptor activity	IEP	Predicted GO
MF	GO:0042800	histone methyltransferase activity (H3-K4 specific)	IEP	Predicted GO
CC	GO:0043235	receptor complex	IEP	Predicted GO
BP	GO:0044036	cell wall macromolecule metabolic process	IEP	Predicted GO
BP	GO:0044038	cell wall macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
CC	GO:0044312	crystalloid	IEP	Predicted GO
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
MF	GO:0046974	histone methyltransferase activity (H3-K9 specific)	IEP	Predicted GO
BP	GO:0051567	histone H3-K9 methylation	IEP	Predicted GO
BP	GO:0051568	histone H3-K4 methylation	IEP	Predicted GO
BP	GO:0061647	histone H3-K9 modification	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
MF	GO:0070569	uridylyltransferase activity	IEP	Predicted GO
BP	GO:0070589	cellular component macromolecule biosynthetic process	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
CC	GO:0098802	plasma membrane receptor complex	IEP	Predicted GO
BP	GO:0120009	intermembrane lipid transfer	IEP	Predicted GO
MF	GO:0120013	intermembrane lipid transfer activity	IEP	Predicted GO
BP	GO:1902298	cell cycle DNA replication maintenance of fidelity	IEP	Predicted GO
CC	GO:1902495	transmembrane transporter complex	IEP	Predicted GO
CC	GO:1990351	transporter complex	IEP	Predicted GO
BP	GO:1990426	mitotic recombination-dependent replication fork processing	IEP	Predicted GO
BP	GO:1990505	mitotic DNA replication maintenance of fidelity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR014882	CathepsinC_exc	20	201
IPR000668	Peptidase_C1A_C	295	570

External Links

PlasmoDB	2277.t00458
PlasmoDB	811510
PlasmoDB	MAL12P1.457
PlasmoDB	PFL2290w

PF3D7_1247800 (DPAP2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation