PF3D7_1343700 (Kelch13)

Aliases : Kelch13

Description : SSF117281: Kelch-type beta propeller, SSF54695: SKP1/BTB/POZ domain superfamily. Pfam domain(s): PF02214: BTB/POZ domain, PF13418: "Galactose oxidase, central domain", PF01344: Kelch motif.

Gene families : OG_01_0001956 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001956_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1343700
Cluster	P. falciparum: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1356700	Kelch13	SSF54695: SKP1/BTB/POZ domain superfamily, SSF50965:...	0.04	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IDA	PlasmoDB
CC	GO:0005783	endoplasmic reticulum	IDA	PlasmoDB
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IDA	PlasmoDB
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043933	protein-containing complex subunit organization	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051259	protein complex oligomerization	None	Extended
BP	GO:0051260	protein homooligomerization	IEA	Interproscan predictions
BP	GO:0051260	protein homooligomerization	IEA	PlasmoDB
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0002028	regulation of sodium ion transport	IEP	Predicted GO
MF	GO:0004012	phospholipid-translocating ATPase activity	IEP	Predicted GO
MF	GO:0004301	epoxide hydrolase activity	IEP	Predicted GO
MF	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity	IEP	Predicted GO
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IEP	Predicted GO
MF	GO:0004354	glutamate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004467	long-chain fatty acid-CoA ligase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006464	cellular protein modification process	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0006793	phosphorus metabolic process	IEP	Predicted GO
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006869	lipid transport	IEP	Predicted GO
BP	GO:0006900	vesicle budding from membrane	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
BP	GO:0010959	regulation of metal ion transport	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
MF	GO:0015645	fatty acid ligase activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0015908	fatty acid transport	IEP	Predicted GO
BP	GO:0015909	long-chain fatty acid transport	IEP	Predicted GO
BP	GO:0015917	aminophospholipid transport	IEP	Predicted GO
BP	GO:0016050	vesicle organization	IEP	Predicted GO
MF	GO:0016301	kinase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016405	CoA-ligase activity	IEP	Predicted GO
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	Predicted GO
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016803	ether hydrolase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0016878	acid-thiol ligase activity	IEP	Predicted GO
BP	GO:0019368	fatty acid elongation, unsaturated fatty acid	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
CC	GO:0020007	apical complex	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
BP	GO:0030497	fatty acid elongation	IEP	Predicted GO
MF	GO:0030507	spectrin binding	IEP	Predicted GO
BP	GO:0031204	posttranslational protein targeting to membrane, translocation	IEP	Predicted GO
CC	GO:0031207	Sec62/Sec63 complex	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
CC	GO:0033643	host cell part	IEP	Predicted GO
CC	GO:0033646	host intracellular part	IEP	Predicted GO
CC	GO:0033655	host cell cytoplasm part	IEP	Predicted GO
BP	GO:0036211	protein modification process	IEP	Predicted GO
BP	GO:0042000	translocation of peptides or proteins into host	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
CC	GO:0043230	extracellular organelle	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
BP	GO:0043412	macromolecule modification	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
CC	GO:0044228	host cell surface	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044417	translocation of molecules into host	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0044538	host cell periphery	IEP	Predicted GO
BP	GO:0044766	multi-organism transport	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051808	translocation of peptides or proteins into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051836	translocation of molecules into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0055088	lipid homeostasis	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:1902579	multi-organism localization	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003131	T1-type_BTB	352	438
IPR006652	Kelch_1	444	477
IPR006652	Kelch_1	631	662
IPR006652	Kelch_1	574	615
IPR006652	Kelch_1	527	572

External Links

PlasmoDB	814205
PlasmoDB	PF13_0238

PF3D7_1343700 (Kelch13)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation