PF3D7_1362300 (TMCO1)

Aliases : TMCO1

Description : No superfamily available. Pfam domain(s): PF01956: Integral membrane protein EMC3/TMCO1-like.

Gene families : OG_01_0001516 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001516_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1362300
Cluster	P. falciparum: Cluster_10

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005216	ion channel activity	None	Extended
MF	GO:0005261	cation channel activity	None	Extended
MF	GO:0005262	calcium channel activity	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006873	cellular ion homeostasis	None	Extended
BP	GO:0006874	cellular calcium ion homeostasis	None	Extended
BP	GO:0006875	cellular metal ion homeostasis	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008324	cation transmembrane transporter activity	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015085	calcium ion transmembrane transporter activity	None	Extended
MF	GO:0015267	channel activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
CC	GO:0016020	membrane	IEA	Interproscan predictions
CC	GO:0016020	membrane	IEA	PlasmoDB
CC	GO:0016021	integral component of membrane	None	Extended
BP	GO:0019725	cellular homeostasis	None	Extended
MF	GO:0022803	passive transmembrane transporter activity	None	Extended
MF	GO:0022838	substrate-specific channel activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0022890	inorganic cation transmembrane transporter activity	None	Extended
BP	GO:0030003	cellular cation homeostasis	None	Extended
CC	GO:0030176	integral component of endoplasmic reticulum membrane	IEA	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	None	Extended
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	IEA	PlasmoDB
BP	GO:0042592	homeostatic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044432	endoplasmic reticulum part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046873	metal ion transmembrane transporter activity	None	Extended
BP	GO:0048878	chemical homeostasis	None	Extended
BP	GO:0050801	ion homeostasis	None	Extended
BP	GO:0055065	metal ion homeostasis	None	Extended
BP	GO:0055074	calcium ion homeostasis	None	Extended
BP	GO:0055080	cation homeostasis	None	Extended
BP	GO:0055082	cellular chemical homeostasis	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0072503	cellular divalent inorganic cation homeostasis	None	Extended
BP	GO:0072507	divalent inorganic cation homeostasis	None	Extended
BP	GO:0098771	inorganic ion homeostasis	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000030	mannosyltransferase activity	IEP	Predicted GO
BP	GO:0000122	negative regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000439	transcription factor TFIIH core complex	IEP	Predicted GO
CC	GO:0000930	gamma-tubulin complex	IEP	Predicted GO
BP	GO:0001817	regulation of cytokine production	IEP	Predicted GO
BP	GO:0001818	negative regulation of cytokine production	IEP	Predicted GO
MF	GO:0003712	transcription coregulator activity	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0003714	transcription corepressor activity	IEP	Predicted GO
MF	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity	IEP	Predicted GO
MF	GO:0004661	protein geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0004663	Rab geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0004766	spermidine synthase activity	IEP	Predicted GO
MF	GO:0005253	anion channel activity	IEP	Predicted GO
MF	GO:0005254	chloride channel activity	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005732	small nucleolar ribonucleoprotein complex	IEP	Predicted GO
CC	GO:0005968	Rab-protein geranylgeranyltransferase complex	IEP	Predicted GO
BP	GO:0006289	nucleotide-excision repair	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006357	regulation of transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006493	protein O-linked glycosylation	IEP	Predicted GO
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Predicted GO
BP	GO:0006595	polyamine metabolic process	IEP	Predicted GO
BP	GO:0006596	polyamine biosynthetic process	IEP	Predicted GO
BP	GO:0007020	microtubule nucleation	IEP	Predicted GO
BP	GO:0008216	spermidine metabolic process	IEP	Predicted GO
BP	GO:0008295	spermidine biosynthetic process	IEP	Predicted GO
MF	GO:0008318	protein prenyltransferase activity	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009308	amine metabolic process	IEP	Predicted GO
BP	GO:0009309	amine biosynthetic process	IEP	Predicted GO
BP	GO:0009889	regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Predicted GO
BP	GO:0010468	regulation of gene expression	IEP	Predicted GO
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Predicted GO
MF	GO:0015103	inorganic anion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015108	chloride transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016192	vesicle-mediated transport	IEP	Predicted GO
CC	GO:0016272	prefoldin complex	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
BP	GO:0018342	protein prenylation	IEP	Predicted GO
BP	GO:0018344	protein geranylgeranylation	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
CC	GO:0030008	TRAPP complex	IEP	Predicted GO
CC	GO:0030121	AP-1 adaptor complex	IEP	Predicted GO
CC	GO:0030131	clathrin adaptor complex	IEP	Predicted GO
BP	GO:0031122	cytoplasmic microtubule organization	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Predicted GO
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Predicted GO
MF	GO:0031404	chloride ion binding	IEP	Predicted GO
BP	GO:0032675	regulation of interleukin-6 production	IEP	Predicted GO
BP	GO:0032715	negative regulation of interleukin-6 production	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	IEP	Predicted GO
CC	GO:0034399	nuclear periphery	IEP	Predicted GO
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Predicted GO
BP	GO:0044106	cellular amine metabolic process	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044450	microtubule organizing center part	IEP	Predicted GO
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0048519	negative regulation of biological process	IEP	Predicted GO
BP	GO:0050794	regulation of cellular process	IEP	Predicted GO
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0051239	regulation of multicellular organismal process	IEP	Predicted GO
BP	GO:0051241	negative regulation of multicellular organismal process	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Predicted GO
CC	GO:0071013	catalytic step 2 spliceosome	IEP	Predicted GO
BP	GO:0080090	regulation of primary metabolic process	IEP	Predicted GO
BP	GO:0097164	ammonium ion metabolic process	IEP	Predicted GO
BP	GO:0097354	prenylation	IEP	Predicted GO
BP	GO:0097435	supramolecular fiber organization	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1990234	transferase complex	IEP	Predicted GO
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002809	EMC3/TMCO1	11	169

External Links

PlasmoDB	814291
PlasmoDB	PF13_0331

PF3D7_1362300 (TMCO1)

Expression Profile

Co-expression Networks

Functional Annotation