PF3D7_1408000 (PMII)

Aliases : PMII

Description : SSF50630: Aspartic peptidase domain superfamily. Pfam domain(s): PF00026: Eukaryotic aspartyl protease.

Gene families : OG_01_0000207 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000207_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1408000
Cluster	P. falciparum: Cluster_44

Type	GO Term	Name	Evidence	Source
CC	GO:0000323	lytic vacuole	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004190	aspartic-type endopeptidase activity	TAS	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005764	lysosome	None	Extended
CC	GO:0005767	secondary lysosome	None	Extended
CC	GO:0005773	vacuole	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
CC	GO:0016020	membrane	IEA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020020	food vacuole	IDA	PlasmoDB
BP	GO:0020027	hemoglobin metabolic process	None	Extended
CC	GO:0030139	endocytic vesicle	None	Extended
BP	GO:0030163	protein catabolic process	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
CC	GO:0032010	phagolysosome	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042493	response to drug	IMP	PlasmoDB
BP	GO:0042540	hemoglobin catabolic process	TAS	PlasmoDB
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
CC	GO:0045335	phagocytic vesicle	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
MF	GO:0070001	aspartic-type peptidase activity	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0097708	intracellular vesicle	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901565	organonitrogen compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003729	mRNA binding	IEP	Predicted GO
MF	GO:0004766	spermidine synthase activity	IEP	Predicted GO
MF	GO:0004814	arginine-tRNA ligase activity	IEP	Predicted GO
BP	GO:0006420	arginyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006446	regulation of translational initiation	IEP	Predicted GO
BP	GO:0006576	cellular biogenic amine metabolic process	IEP	Predicted GO
BP	GO:0006595	polyamine metabolic process	IEP	Predicted GO
BP	GO:0006596	polyamine biosynthetic process	IEP	Predicted GO
BP	GO:0008216	spermidine metabolic process	IEP	Predicted GO
BP	GO:0008295	spermidine biosynthetic process	IEP	Predicted GO
BP	GO:0009308	amine metabolic process	IEP	Predicted GO
BP	GO:0009309	amine biosynthetic process	IEP	Predicted GO
MF	GO:0015267	channel activity	IEP	Predicted GO
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
MF	GO:0022803	passive transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030008	TRAPP complex	IEP	Predicted GO
CC	GO:0030532	small nuclear ribonucleoprotein complex	IEP	Predicted GO
CC	GO:0033647	host intracellular organelle	IEP	Predicted GO
CC	GO:0033648	host intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0035915	pore formation in membrane of other organism	IEP	Predicted GO
BP	GO:0042401	cellular biogenic amine biosynthetic process	IEP	Predicted GO
BP	GO:0044106	cellular amine metabolic process	IEP	Predicted GO
CC	GO:0044161	host cell cytoplasmic vesicle	IEP	Predicted GO
BP	GO:0044657	pore formation in membrane of other organism during symbiotic interaction	IEP	Predicted GO
BP	GO:0044658	pore formation in membrane of host by symbiont	IEP	Predicted GO
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	IEP	Predicted GO
BP	GO:0051673	membrane disruption in other organism	IEP	Predicted GO
BP	GO:0052025	modification by symbiont of host cell membrane	IEP	Predicted GO
BP	GO:0052043	modification by symbiont of host cellular component	IEP	Predicted GO
BP	GO:0052111	modification by symbiont of host structure	IEP	Predicted GO
BP	GO:0052185	modification of structure of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052188	modification of cellular component in other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052332	modification by organism of membrane in other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0097164	ammonium ion metabolic process	IEP	Predicted GO
CC	GO:0097525	spliceosomal snRNP complex	IEP	Predicted GO
CC	GO:0097526	spliceosomal tri-snRNP complex	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
CC	GO:0120114	Sm-like protein family complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR033121	PEPTIDASE_A1	140	448

External Links

PlasmoDB	811659
PlasmoDB	PF14_0077

PF3D7_1408000 (PMII)

Expression Profile

Co-expression Networks

Functional Annotation