PF3D7_1420400 (GlyRS)

Aliases : GlyRS

Description : SSF55681: No description available, SSF52954: No description available. Pfam domain(s): PF03129: Anticodon binding domain.

Gene families : OG_01_0001287 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001287_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1420400
Cluster	P. falciparum: Cluster_28

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1022800	GlyRS	SSF52954: 20-02-2019, SSF55681: 20-02-2019. Pfam...	0.03	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	None	Extended
MF	GO:0004820	glycine-tRNA ligase activity	ISS	PlasmoDB
MF	GO:0004820	glycine-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	None	Extended
BP	GO:0006426	glycyl-tRNA aminoacylation	ISS	PlasmoDB
BP	GO:0006426	glycyl-tRNA aminoacylation	IEA	PlasmoDB
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0020011	apicoplast	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000054	ribosomal subunit export from nucleus	IEP	Predicted GO
BP	GO:0000055	ribosomal large subunit export from nucleus	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0003921	GMP synthase activity	IEP	Predicted GO
MF	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004177	aminopeptidase activity	IEP	Predicted GO
MF	GO:0004347	glucose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004590	orotidine-5'-phosphate decarboxylase activity	IEP	Predicted GO
MF	GO:0004815	aspartate-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004822	isoleucine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004829	threonine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005654	nucleoplasm	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005832	chaperonin-containing T-complex	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006006	glucose metabolic process	IEP	Predicted GO
BP	GO:0006094	gluconeogenesis	IEP	Predicted GO
BP	GO:0006109	regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0006177	GMP biosynthetic process	IEP	Predicted GO
BP	GO:0006206	pyrimidine nucleobase metabolic process	IEP	Predicted GO
BP	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006405	RNA export from nucleus	IEP	Predicted GO
BP	GO:0006422	aspartyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006428	isoleucyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006435	threonyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006536	glutamate metabolic process	IEP	Predicted GO
BP	GO:0006538	glutamate catabolic process	IEP	Predicted GO
BP	GO:0006611	protein export from nucleus	IEP	Predicted GO
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008169	C-methyltransferase activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008237	metallopeptidase activity	IEP	Predicted GO
MF	GO:0008238	exopeptidase activity	IEP	Predicted GO
MF	GO:0008320	protein transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008479	queuine tRNA-ribosyltransferase activity	IEP	Predicted GO
BP	GO:0008616	queuosine biosynthetic process	IEP	Predicted GO
BP	GO:0009063	cellular amino acid catabolic process	IEP	Predicted GO
BP	GO:0009065	glutamine family amino acid catabolic process	IEP	Predicted GO
BP	GO:0009112	nucleobase metabolic process	IEP	Predicted GO
BP	GO:0009116	nucleoside metabolic process	IEP	Predicted GO
BP	GO:0009117	nucleotide metabolic process	IEP	Predicted GO
BP	GO:0009119	ribonucleoside metabolic process	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009163	nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	IEP	Predicted GO
MF	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
BP	GO:0010322	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010323	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	IEP	Predicted GO
BP	GO:0010563	negative regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0010565	regulation of cellular ketone metabolic process	IEP	Predicted GO
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	IEP	Predicted GO
MF	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016054	organic acid catabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016434	rRNA (cytosine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	IEP	Predicted GO
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
BP	GO:0018130	heterocycle biosynthetic process	IEP	Predicted GO
MF	GO:0019203	carbohydrate phosphatase activity	IEP	Predicted GO
BP	GO:0019216	regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0019319	hexose biosynthetic process	IEP	Predicted GO
BP	GO:0019747	regulation of isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0019856	pyrimidine nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
MF	GO:0022884	macromolecule transmembrane transporter activity	IEP	Predicted GO
MF	GO:0030544	Hsp70 protein binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0030686	90S preribosome	IEP	Predicted GO
CC	GO:0030687	preribosome, large subunit precursor	IEP	Predicted GO
CC	GO:0030688	preribosome, small subunit precursor	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031428	box C/D snoRNP complex	IEP	Predicted GO
BP	GO:0031503	protein-containing complex localization	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033750	ribosome localization	IEP	Predicted GO
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0034462	small-subunit processome assembly	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042273	ribosomal large subunit biogenesis	IEP	Predicted GO
BP	GO:0042451	purine nucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0042455	ribonucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043649	dicarboxylic acid catabolic process	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
BP	GO:0045827	negative regulation of isoprenoid metabolic process	IEP	Predicted GO
BP	GO:0045833	negative regulation of lipid metabolic process	IEP	Predicted GO
BP	GO:0045912	negative regulation of carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0045936	negative regulation of phosphate metabolic process	IEP	Predicted GO
BP	GO:0046037	GMP metabolic process	IEP	Predicted GO
BP	GO:0046112	nucleobase biosynthetic process	IEP	Predicted GO
BP	GO:0046116	queuosine metabolic process	IEP	Predicted GO
BP	GO:0046129	purine ribonucleoside biosynthetic process	IEP	Predicted GO
BP	GO:0046364	monosaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0046395	carboxylic acid catabolic process	IEP	Predicted GO
BP	GO:0046890	regulation of lipid biosynthetic process	IEP	Predicted GO
MF	GO:0050308	sugar-phosphatase activity	IEP	Predicted GO
BP	GO:0051055	negative regulation of lipid biosynthetic process	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0051656	establishment of organelle localization	IEP	Predicted GO
MF	GO:0051879	Hsp90 protein binding	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
BP	GO:0062012	regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0062014	negative regulation of small molecule metabolic process	IEP	Predicted GO
BP	GO:0071071	regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0071072	negative regulation of phospholipid biosynthetic process	IEP	Predicted GO
BP	GO:0071426	ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:0090407	organophosphate biosynthetic process	IEP	Predicted GO
CC	GO:0101031	chaperone complex	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901070	guanosine-containing compound biosynthetic process	IEP	Predicted GO
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Predicted GO
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Predicted GO
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Predicted GO
BP	GO:1901657	glycosyl compound metabolic process	IEP	Predicted GO
BP	GO:1901659	glycosyl compound biosynthetic process	IEP	Predicted GO
BP	GO:1903725	regulation of phospholipid metabolic process	IEP	Predicted GO
BP	GO:1903726	negative regulation of phospholipid metabolic process	IEP	Predicted GO
MF	GO:1904680	peptide transmembrane transporter activity	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004154	Anticodon-bd	773	863

External Links

PlasmoDB	811779
PlasmoDB	PF14_0198

PF3D7_1420400 (GlyRS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation