PF3D7_1462800 (GAPDH)


Aliases : GAPDH

Description : SSF51735: NAD(P)-binding domain superfamily, SSF55347: No description available. Pfam domain(s): PF02800: "Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain", PF00044: "Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain".


Gene families : OG_01_0000378 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000378_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_1462800
Cluster P. falciparum: Cluster_11

Target Alias Description ECC score Gene Family Method Actions
PBANKA_1326400 GAPDH SSF55347: 20-02-2019, SSF51735: NAD(P)-binding domain... 0.16 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity TAS PlasmoDB
MF GO:0005515 protein binding IPI PlasmoDB
CC GO:0005829 cytosol IDA PlasmoDB
BP GO:0006006 glucose metabolic process IEA PlasmoDB
BP GO:0006094 gluconeogenesis TAS PlasmoDB
BP GO:0006096 glycolytic process TAS PlasmoDB
CC GO:0009986 cell surface ISO PlasmoDB
CC GO:0016020 membrane IDA PlasmoDB
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA Interproscan predictions
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA PlasmoDB
BP GO:0030260 entry into host cell ISO PlasmoDB
MF GO:0050661 NADP binding IEA PlasmoDB
MF GO:0051287 NAD binding IEA PlasmoDB
BP GO:0055114 oxidation-reduction process IEA Interproscan predictions
BP GO:0055114 oxidation-reduction process IEA PlasmoDB
CC GO:1903561 extracellular vesicle RCA PlasmoDB
Type GO Term Name Evidence Source
CC GO:0000015 phosphopyruvate hydratase complex IEP Predicted GO
BP GO:0000045 autophagosome assembly IEP Predicted GO
MF GO:0000287 magnesium ion binding IEP Predicted GO
BP GO:0000413 protein peptidyl-prolyl isomerization IEP Predicted GO
BP GO:0001678 cellular glucose homeostasis IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
BP GO:0002253 activation of immune response IEP Predicted GO
BP GO:0002684 positive regulation of immune system process IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003725 double-stranded RNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Predicted GO
MF GO:0003924 GTPase activity IEP Predicted GO
MF GO:0004000 adenosine deaminase activity IEP Predicted GO
MF GO:0004013 adenosylhomocysteinase activity IEP Predicted GO
MF GO:0004017 adenylate kinase activity IEP Predicted GO
MF GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity IEP Predicted GO
MF GO:0004396 hexokinase activity IEP Predicted GO
MF GO:0004457 lactate dehydrogenase activity IEP Predicted GO
MF GO:0004459 L-lactate dehydrogenase activity IEP Predicted GO
MF GO:0004601 peroxidase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004634 phosphopyruvate hydratase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004743 pyruvate kinase activity IEP Predicted GO
MF GO:0004749 ribose phosphate diphosphokinase activity IEP Predicted GO
MF GO:0004751 ribose-5-phosphate isomerase activity IEP Predicted GO
MF GO:0004784 superoxide dismutase activity IEP Predicted GO
MF GO:0004807 triose-phosphate isomerase activity IEP Predicted GO
MF GO:0004824 lysine-tRNA ligase activity IEP Predicted GO
MF GO:0005102 signaling receptor binding IEP Predicted GO
MF GO:0005125 cytokine activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
MF GO:0005536 glucose binding IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005654 nucleoplasm IEP Predicted GO
CC GO:0005746 mitochondrial respirasome IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005850 eukaryotic translation initiation factor 2 complex IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006098 pentose-phosphate shunt IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006166 purine ribonucleoside salvage IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006430 lysyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006448 regulation of translational elongation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006493 protein O-linked glycosylation IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006627 protein processing involved in protein targeting to mitochondrion IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006801 superoxide metabolic process IEP Predicted GO
BP GO:0006979 response to oxidative stress IEP Predicted GO
BP GO:0007033 vacuole organization IEP Predicted GO
BP GO:0007154 cell communication IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008379 thioredoxin peroxidase activity IEP Predicted GO
BP GO:0008614 pyridoxine metabolic process IEP Predicted GO
BP GO:0008615 pyridoxine biosynthetic process IEP Predicted GO
BP GO:0009052 pentose-phosphate shunt, non-oxidative branch IEP Predicted GO
MF GO:0009055 electron transfer activity IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009119 ribonucleoside metabolic process IEP Predicted GO
BP GO:0009124 nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009126 purine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009127 purine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009156 ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009161 ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009167 purine ribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0009893 positive regulation of metabolic process IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010604 positive regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0010628 positive regulation of gene expression IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
BP GO:0015959 diadenosine polyphosphate metabolic process IEP Predicted GO
BP GO:0015960 diadenosine polyphosphate biosynthetic process IEP Predicted GO
BP GO:0015965 diadenosine tetraphosphate metabolic process IEP Predicted GO
BP GO:0015966 diadenosine tetraphosphate biosynthetic process IEP Predicted GO
MF GO:0016209 antioxidant activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016684 oxidoreductase activity, acting on peroxide as acceptor IEP Predicted GO
MF GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016778 diphosphotransferase activity IEP Predicted GO
MF GO:0016801 hydrolase activity, acting on ether bonds IEP Predicted GO
MF GO:0016802 trialkylsulfonium hydrolase activity IEP Predicted GO
MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
MF GO:0016859 cis-trans isomerase activity IEP Predicted GO
MF GO:0016860 intramolecular oxidoreductase activity IEP Predicted GO
MF GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEP Predicted GO
MF GO:0016868 intramolecular transferase activity, phosphotransferases IEP Predicted GO
CC GO:0017087 mitochondrial processing peptidase complex IEP Predicted GO
BP GO:0018208 peptidyl-proline modification IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
CC GO:0019005 SCF ubiquitin ligase complex IEP Predicted GO
MF GO:0019153 protein-disulfide reductase (glutathione) activity IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
MF GO:0019239 deaminase activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019682 glyceraldehyde-3-phosphate metabolic process IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
BP GO:0020012 evasion or tolerance of host immune response IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
MF GO:0030246 carbohydrate binding IEP Predicted GO
MF GO:0030545 receptor regulator activity IEP Predicted GO
BP GO:0030682 evasion or tolerance of host defense response IEP Predicted GO
MF GO:0030955 potassium ion binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
MF GO:0031420 alkali metal ion binding IEP Predicted GO
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Predicted GO
BP GO:0031668 cellular response to extracellular stimulus IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033500 carbohydrate homeostasis IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
BP GO:0034982 mitochondrial protein processing IEP Predicted GO
BP GO:0042026 protein refolding IEP Predicted GO
BP GO:0042221 response to chemical IEP Predicted GO
BP GO:0042262 DNA protection IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0042493 response to drug IEP Predicted GO
BP GO:0042592 homeostatic process IEP Predicted GO
BP GO:0042593 glucose homeostasis IEP Predicted GO
BP GO:0042816 vitamin B6 metabolic process IEP Predicted GO
BP GO:0042819 vitamin B6 biosynthetic process IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
BP GO:0043094 cellular metabolic compound salvage IEP Predicted GO
BP GO:0043101 purine-containing compound salvage IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043174 nucleoside salvage IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043244 regulation of protein complex disassembly IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
BP GO:0044413 avoidance of host defenses IEP Predicted GO
BP GO:0044415 evasion or tolerance of host defenses IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
BP GO:0045116 protein neddylation IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
MF GO:0048018 receptor ligand activity IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
BP GO:0048518 positive regulation of biological process IEP Predicted GO
BP GO:0048584 positive regulation of response to stimulus IEP Predicted GO
MF GO:0050145 nucleoside monophosphate kinase activity IEP Predicted GO
BP GO:0050778 positive regulation of immune response IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051130 positive regulation of cellular component organization IEP Predicted GO
BP GO:0051156 glucose 6-phosphate metabolic process IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0051260 protein homooligomerization IEP Predicted GO
BP GO:0051262 protein tetramerization IEP Predicted GO
BP GO:0051289 protein homotetramerization IEP Predicted GO
BP GO:0051382 kinetochore assembly IEP Predicted GO
BP GO:0051383 kinetochore organization IEP Predicted GO
MF GO:0051920 peroxiredoxin activity IEP Predicted GO
BP GO:0052200 response to host defenses IEP Predicted GO
BP GO:0052572 response to host immune response IEP Predicted GO
BP GO:0065008 regulation of biological quality IEP Predicted GO
CC GO:0070469 respirasome IEP Predicted GO
BP GO:0070925 organelle assembly IEP Predicted GO
CC GO:0070971 endoplasmic reticulum exit site IEP Predicted GO
BP GO:0071496 cellular response to external stimulus IEP Predicted GO
BP GO:0072523 purine-containing compound catabolic process IEP Predicted GO
BP GO:0072593 reactive oxygen species metabolic process IEP Predicted GO
BP GO:0075136 response to host IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
BP GO:1905037 autophagosome organization IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR020828 GlycerAld_3-P_DH_NAD(P)-bd 5 104
IPR020829 GlycerAld_3-P_DH_cat 158 317
PlasmoDB 812180
PlasmoDB PF14_0598