PBANKA_0605300 (EIF5)

Aliases : EIF5

Description : SSF100966: Translation initiation factor IF2/IF5, N-terminal, SSF75689: Translation initiation factor IF2/IF5, zinc-binding. Pfam domain(s): PF01873: Domain found in IF2B/IF5, PF02020: eIF4-gamma/eIF5/eIF2-epsilon.

Gene families : OG_01_0000774 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000774_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_0605300
Cluster	P. berghei: Cluster_4

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	None	Extended
MF	GO:0003743	translation initiation factor activity	ISS	PlasmoDB
MF	GO:0003743	translation initiation factor activity	IEA	Interproscan predictions
MF	GO:0003743	translation initiation factor activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	Interproscan predictions
MF	GO:0005515	protein binding	IEA	PlasmoDB
BP	GO:0006413	translational initiation	IEA	Interproscan predictions
BP	GO:0006413	translational initiation	IEA	PlasmoDB
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006446	regulation of translational initiation	ISS	PlasmoDB
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0000175	3'-5'-exoribonuclease activity	IEP	Predicted GO
CC	GO:0000177	cytoplasmic exosome (RNase complex)	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0001522	pseudouridine synthesis	IEP	Predicted GO
BP	GO:0002143	tRNA wobble position uridine thiolation	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004476	mannose-6-phosphate isomerase activity	IEP	Predicted GO
MF	GO:0004651	polynucleotide 5'-phosphatase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004816	asparagine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005092	GDP-dissociation inhibitor activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005666	RNA polymerase III complex	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006399	tRNA metabolic process	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006421	asparaginyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Predicted GO
BP	GO:0007264	small GTPase mediated signal transduction	IEP	Predicted GO
BP	GO:0008033	tRNA processing	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEP	Predicted GO
BP	GO:0009266	response to temperature stimulus	IEP	Predicted GO
BP	GO:0009408	response to heat	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0016049	cell growth	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016073	snRNA metabolic process	IEP	Predicted GO
BP	GO:0016556	mRNA modification	IEP	Predicted GO
MF	GO:0016779	nucleotidyltransferase activity	IEP	Predicted GO
MF	GO:0016785	transferase activity, transferring selenium-containing groups	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016866	intramolecular transferase activity	IEP	Predicted GO
MF	GO:0016874	ligase activity	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0030014	CCR4-NOT complex	IEP	Predicted GO
MF	GO:0030544	Hsp70 protein binding	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
BP	GO:0031120	snRNA pseudouridine synthesis	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0032774	RNA biosynthetic process	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034227	tRNA thio-modification	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0040007	growth	IEP	Predicted GO
BP	GO:0040031	snRNA modification	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043170	macromolecule metabolic process	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0046483	heterocycle metabolic process	IEP	Predicted GO
MF	GO:0051879	Hsp90 protein binding	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
MF	GO:0098518	polynucleotide phosphatase activity	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Predicted GO
BP	GO:1990481	mRNA pseudouridine synthesis	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR002735	Transl_init_fac_IF2/IF5	8	126
IPR003307	W2_domain	335	439

External Links

PlasmoDB	PB000468.02.0
PlasmoDB	PBANKA_060530

PBANKA_0605300 (EIF5)

Expression Profile

Co-expression Networks

Functional Annotation