PBANKA_1125600


Description : SSF50800: Pyruvate kinase-like, insert domain superfamily, SSF52935: Pyruvate kinase, C-terminal domain superfamily, SSF51621: Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily. Pfam domain(s): PF00224: Pyruvate kinase, barrel domain, PF02887: Pyruvate kinase, alpha/beta domain.


Gene families : OG_01_0001454 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001454_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pbe RNA-seq: PBANKA_1125600
Cluster P. berghei: Cluster_36

Target Alias Description ECC score Gene Family Method Actions
PF3D7_0626800 PyrK SSF50800: "Pyruvate kinase-like, insert domain... 0.18 Orthofinderv1.1.8

Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEA Interproscan predictions
MF GO:0000287 magnesium ion binding IEA PlasmoDB
MF GO:0003824 catalytic activity IEA PlasmoDB
MF GO:0004743 pyruvate kinase activity IEA Interproscan predictions
MF GO:0004743 pyruvate kinase activity IEA PlasmoDB
BP GO:0006096 glycolytic process IEA Interproscan predictions
BP GO:0006096 glycolytic process IEA PlasmoDB
MF GO:0030955 potassium ion binding IEA Interproscan predictions
MF GO:0030955 potassium ion binding IEA PlasmoDB
Type GO Term Name Evidence Source
CC GO:0000015 phosphopyruvate hydratase complex IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
CC GO:0000323 lytic vacuole IEP Predicted GO
BP GO:0000380 alternative mRNA splicing, via spliceosome IEP Predicted GO
MF GO:0000900 translation repressor activity, mRNA regulatory element binding IEP Predicted GO
BP GO:0001678 cellular glucose homeostasis IEP Predicted GO
BP GO:0001731 formation of translation preinitiation complex IEP Predicted GO
BP GO:0001817 regulation of cytokine production IEP Predicted GO
BP GO:0001818 negative regulation of cytokine production IEP Predicted GO
MF GO:0001882 nucleoside binding IEP Predicted GO
MF GO:0001883 purine nucleoside binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003688 DNA replication origin binding IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0003735 structural constituent of ribosome IEP Predicted GO
MF GO:0003743 translation initiation factor activity IEP Predicted GO
MF GO:0003746 translation elongation factor activity IEP Predicted GO
MF GO:0003924 GTPase activity IEP Predicted GO
MF GO:0003938 IMP dehydrogenase activity IEP Predicted GO
MF GO:0004013 adenosylhomocysteinase activity IEP Predicted GO
MF GO:0004177 aminopeptidase activity IEP Predicted GO
MF GO:0004396 hexokinase activity IEP Predicted GO
MF GO:0004416 hydroxyacylglutathione hydrolase activity IEP Predicted GO
MF GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEP Predicted GO
MF GO:0004516 nicotinate phosphoribosyltransferase activity IEP Predicted GO
MF GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004619 phosphoglycerate mutase activity IEP Predicted GO
MF GO:0004634 phosphopyruvate hydratase activity IEP Predicted GO
MF GO:0004731 purine-nucleoside phosphorylase activity IEP Predicted GO
MF GO:0004766 spermidine synthase activity IEP Predicted GO
MF GO:0004814 arginine-tRNA ligase activity IEP Predicted GO
MF GO:0004828 serine-tRNA ligase activity IEP Predicted GO
MF GO:0005092 GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005093 Rab GDP-dissociation inhibitor activity IEP Predicted GO
MF GO:0005198 structural molecule activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0005525 GTP binding IEP Predicted GO
MF GO:0005536 glucose binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005622 intracellular IEP Predicted GO
CC GO:0005737 cytoplasm IEP Predicted GO
CC GO:0005764 lysosome IEP Predicted GO
CC GO:0005767 secondary lysosome IEP Predicted GO
CC GO:0005773 vacuole IEP Predicted GO
CC GO:0005829 cytosol IEP Predicted GO
CC GO:0005832 chaperonin-containing T-complex IEP Predicted GO
CC GO:0005840 ribosome IEP Predicted GO
CC GO:0005850 eukaryotic translation initiation factor 2 complex IEP Predicted GO
CC GO:0005852 eukaryotic translation initiation factor 3 complex IEP Predicted GO
CC GO:0005853 eukaryotic translation elongation factor 1 complex IEP Predicted GO
CC GO:0005854 nascent polypeptide-associated complex IEP Predicted GO
CC GO:0005856 cytoskeleton IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006089 lactate metabolic process IEP Predicted GO
BP GO:0006109 regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0006148 inosine catabolic process IEP Predicted GO
BP GO:0006152 purine nucleoside catabolic process IEP Predicted GO
BP GO:0006412 translation IEP Predicted GO
BP GO:0006413 translational initiation IEP Predicted GO
BP GO:0006414 translational elongation IEP Predicted GO
BP GO:0006417 regulation of translation IEP Predicted GO
BP GO:0006420 arginyl-tRNA aminoacylation IEP Predicted GO
BP GO:0006434 seryl-tRNA aminoacylation IEP Predicted GO
BP GO:0006449 regulation of translational termination IEP Predicted GO
BP GO:0006452 translational frameshifting IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006458 'de novo' protein folding IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006518 peptide metabolic process IEP Predicted GO
BP GO:0006595 polyamine metabolic process IEP Predicted GO
BP GO:0006596 polyamine biosynthetic process IEP Predicted GO
BP GO:0006913 nucleocytoplasmic transport IEP Predicted GO
BP GO:0007264 small GTPase mediated signal transduction IEP Predicted GO
MF GO:0008135 translation factor activity, RNA binding IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008216 spermidine metabolic process IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008237 metallopeptidase activity IEP Predicted GO
MF GO:0008238 exopeptidase activity IEP Predicted GO
BP GO:0008295 spermidine biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009143 nucleoside triphosphate catabolic process IEP Predicted GO
BP GO:0009164 nucleoside catabolic process IEP Predicted GO
BP GO:0009309 amine biosynthetic process IEP Predicted GO
BP GO:0009435 NAD biosynthetic process IEP Predicted GO
BP GO:0009438 methylglyoxal metabolic process IEP Predicted GO
BP GO:0009891 positive regulation of biosynthetic process IEP Predicted GO
BP GO:0010322 regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010323 negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEP Predicted GO
BP GO:0010557 positive regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010563 negative regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0010565 regulation of cellular ketone metabolic process IEP Predicted GO
BP GO:0010608 posttranscriptional regulation of gene expression IEP Predicted GO
BP GO:0010675 regulation of cellular carbohydrate metabolic process IEP Predicted GO
BP GO:0010677 negative regulation of cellular carbohydrate metabolic process IEP Predicted GO
CC GO:0015934 large ribosomal subunit IEP Predicted GO
CC GO:0015935 small ribosomal subunit IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016763 transferase activity, transferring pentosyl groups IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016801 hydrolase activity, acting on ether bonds IEP Predicted GO
MF GO:0016802 trialkylsulfonium hydrolase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019001 guanyl nucleotide binding IEP Predicted GO
MF GO:0019203 carbohydrate phosphatase activity IEP Predicted GO
BP GO:0019216 regulation of lipid metabolic process IEP Predicted GO
BP GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEP Predicted GO
BP GO:0019357 nicotinate nucleotide biosynthetic process IEP Predicted GO
BP GO:0019358 nicotinate nucleotide salvage IEP Predicted GO
BP GO:0019365 pyridine nucleotide salvage IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019674 NAD metabolic process IEP Predicted GO
BP GO:0019747 regulation of isoprenoid metabolic process IEP Predicted GO
CC GO:0020003 symbiont-containing vacuole IEP Predicted GO
CC GO:0020020 food vacuole IEP Predicted GO
BP GO:0020027 hemoglobin metabolic process IEP Predicted GO
CC GO:0022625 cytosolic large ribosomal subunit IEP Predicted GO
CC GO:0022627 cytosolic small ribosomal subunit IEP Predicted GO
CC GO:0030139 endocytic vesicle IEP Predicted GO
MF GO:0030371 translation repressor activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
BP GO:0031325 positive regulation of cellular metabolic process IEP Predicted GO
BP GO:0031328 positive regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031410 cytoplasmic vesicle IEP Predicted GO
CC GO:0031982 vesicle IEP Predicted GO
CC GO:0032010 phagolysosome IEP Predicted GO
BP GO:0032270 positive regulation of cellular protein metabolic process IEP Predicted GO
MF GO:0032549 ribonucleoside binding IEP Predicted GO
MF GO:0032550 purine ribonucleoside binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
MF GO:0032561 guanyl ribonucleotide binding IEP Predicted GO
BP GO:0032675 regulation of interleukin-6 production IEP Predicted GO
BP GO:0032715 negative regulation of interleukin-6 production IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
BP GO:0033500 carbohydrate homeostasis IEP Predicted GO
BP GO:0034248 regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034250 positive regulation of cellular amide metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0034656 nucleobase-containing small molecule catabolic process IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042026 protein refolding IEP Predicted GO
BP GO:0042182 ketone catabolic process IEP Predicted GO
BP GO:0042401 cellular biogenic amine biosynthetic process IEP Predicted GO
BP GO:0042454 ribonucleoside catabolic process IEP Predicted GO
BP GO:0042540 hemoglobin catabolic process IEP Predicted GO
BP GO:0042593 glucose homeostasis IEP Predicted GO
BP GO:0043043 peptide biosynthetic process IEP Predicted GO
MF GO:0043047 single-stranded telomeric DNA binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043173 nucleotide salvage IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043228 non-membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Predicted GO
BP GO:0043243 positive regulation of protein complex disassembly IEP Predicted GO
BP GO:0043603 cellular amide metabolic process IEP Predicted GO
BP GO:0043604 amide biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0044282 small molecule catabolic process IEP Predicted GO
CC GO:0044391 ribosomal subunit IEP Predicted GO
CC GO:0044422 organelle part IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
CC GO:0044445 cytosolic part IEP Predicted GO
CC GO:0044446 intracellular organelle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
MF GO:0045182 translation regulator activity IEP Predicted GO
CC GO:0045335 phagocytic vesicle IEP Predicted GO
BP GO:0045727 positive regulation of translation IEP Predicted GO
BP GO:0045827 negative regulation of isoprenoid metabolic process IEP Predicted GO
BP GO:0045833 negative regulation of lipid metabolic process IEP Predicted GO
BP GO:0045901 positive regulation of translational elongation IEP Predicted GO
BP GO:0045905 positive regulation of translational termination IEP Predicted GO
BP GO:0045912 negative regulation of carbohydrate metabolic process IEP Predicted GO
BP GO:0045936 negative regulation of phosphate metabolic process IEP Predicted GO
BP GO:0046102 inosine metabolic process IEP Predicted GO
BP GO:0046130 purine ribonucleoside catabolic process IEP Predicted GO
BP GO:0046185 aldehyde catabolic process IEP Predicted GO
BP GO:0046497 nicotinate nucleotide metabolic process IEP Predicted GO
BP GO:0046890 regulation of lipid biosynthetic process IEP Predicted GO
MF GO:0047429 nucleoside-triphosphate diphosphatase activity IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
MF GO:0050308 sugar-phosphatase activity IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
BP GO:0051055 negative regulation of lipid biosynthetic process IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051083 'de novo' cotranslational protein folding IEP Predicted GO
BP GO:0051169 nuclear transport IEP Predicted GO
BP GO:0051173 positive regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051239 regulation of multicellular organismal process IEP Predicted GO
BP GO:0051241 negative regulation of multicellular organismal process IEP Predicted GO
BP GO:0051247 positive regulation of protein metabolic process IEP Predicted GO
BP GO:0051596 methylglyoxal catabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
BP GO:0061727 methylglyoxal catabolic process to lactate IEP Predicted GO
BP GO:0062012 regulation of small molecule metabolic process IEP Predicted GO
BP GO:0062014 negative regulation of small molecule metabolic process IEP Predicted GO
CC GO:0065010 extracellular membrane-bounded organelle IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0071071 regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0071072 negative regulation of phospholipid biosynthetic process IEP Predicted GO
BP GO:0072523 purine-containing compound catabolic process IEP Predicted GO
MF GO:0090079 translation regulator activity, nucleic acid binding IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
CC GO:0097708 intracellular vesicle IEP Predicted GO
MF GO:0098847 sequence-specific single stranded DNA binding IEP Predicted GO
CC GO:0101031 chaperone complex IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901658 glycosyl compound catabolic process IEP Predicted GO
BP GO:1903725 regulation of phospholipid metabolic process IEP Predicted GO
BP GO:1903726 negative regulation of phospholipid metabolic process IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR015793 Pyrv_Knase_brl 37 376
IPR015795 Pyrv_Knase_C 395 508
PlasmoDB PB000521.02.0
PlasmoDB PB301426.00.0
PlasmoDB PBANKA_112560