PBANKA_1143600 (AlaRS)

Aliases : AlaRS

Description : SSF101353: Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily, SSF55681: 20-02-2019, SSF55186: Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily, SSF50447: Translation protein, beta-barrel domain superfamily. Pfam domain(s): PF01411: tRNA synthetases class II (A), PF07973: Threonyl and Alanyl tRNA synthetase second additional domain.

Gene families : OG_01_0001543 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001543_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1143600
Cluster	P. berghei: Cluster_4

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1367700	AlaRS	SSF55681: No description available, SSF55186:...	0.07	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan predictions
MF	GO:0000166	nucleotide binding	IEA	PlasmoDB
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	Interproscan predictions
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0004813	alanine-tRNA ligase activity	IEA	Interproscan predictions
MF	GO:0004813	alanine-tRNA ligase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	IEA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006399	tRNA metabolic process	None	Extended
BP	GO:0006418	tRNA aminoacylation for protein translation	None	Extended
BP	GO:0006419	alanyl-tRNA aminoacylation	IEA	Interproscan predictions
BP	GO:0006419	alanyl-tRNA aminoacylation	IEA	PlasmoDB
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016874	ligase activity	None	Extended
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0020011	apicoplast	ISO	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034660	ncRNA metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043038	amino acid activation	None	Extended
BP	GO:0043039	tRNA aminoacylation	IEA	Interproscan predictions
BP	GO:0043039	tRNA aminoacylation	IEA	PlasmoDB
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:0140101	catalytic activity, acting on a tRNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000175	3'-5'-exoribonuclease activity	IEP	Predicted GO
CC	GO:0000177	cytoplasmic exosome (RNase complex)	IEP	Predicted GO
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
BP	GO:0001522	pseudouridine synthesis	IEP	Predicted GO
MF	GO:0002161	aminoacyl-tRNA editing activity	IEP	Predicted GO
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0003938	IMP dehydrogenase activity	IEP	Predicted GO
MF	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	IEP	Predicted GO
MF	GO:0004516	nicotinate phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004651	polynucleotide 5'-phosphatase activity	IEP	Predicted GO
MF	GO:0004819	glutamine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004827	proline-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004828	serine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004829	threonine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004832	valine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005092	GDP-dissociation inhibitor activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005527	macrolide binding	IEP	Predicted GO
MF	GO:0005528	FK506 binding	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
CC	GO:0005838	proteasome regulatory particle	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006002	fructose 6-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006413	translational initiation	IEP	Predicted GO
BP	GO:0006425	glutaminyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006433	prolyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006434	seryl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006435	threonyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006487	protein N-linked glycosylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0007264	small GTPase mediated signal transduction	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008237	metallopeptidase activity	IEP	Predicted GO
CC	GO:0008250	oligosaccharyltransferase complex	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
BP	GO:0009165	nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0009266	response to temperature stimulus	IEP	Predicted GO
BP	GO:0009408	response to heat	IEP	Predicted GO
BP	GO:0009435	NAD biosynthetic process	IEP	Predicted GO
BP	GO:0009451	RNA modification	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0016073	snRNA metabolic process	IEP	Predicted GO
BP	GO:0016556	mRNA modification	IEP	Predicted GO
MF	GO:0016757	transferase activity, transferring glycosyl groups	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Predicted GO
MF	GO:0016853	isomerase activity	IEP	Predicted GO
MF	GO:0016866	intramolecular transferase activity	IEP	Predicted GO
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
BP	GO:0019357	nicotinate nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019358	nicotinate nucleotide salvage	IEP	Predicted GO
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Predicted GO
BP	GO:0019365	pyridine nucleotide salvage	IEP	Predicted GO
BP	GO:0019674	NAD metabolic process	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
BP	GO:0020027	hemoglobin metabolic process	IEP	Predicted GO
CC	GO:0030014	CCR4-NOT complex	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0031120	snRNA pseudouridine synthesis	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
BP	GO:0040031	snRNA modification	IEP	Predicted GO
BP	GO:0042026	protein refolding	IEP	Predicted GO
BP	GO:0042540	hemoglobin catabolic process	IEP	Predicted GO
BP	GO:0043094	cellular metabolic compound salvage	IEP	Predicted GO
BP	GO:0043173	nucleotide salvage	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Predicted GO
BP	GO:0046497	nicotinate nucleotide metabolic process	IEP	Predicted GO
MF	GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	IEP	Predicted GO
CC	GO:0048471	perinuclear region of cytoplasm	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
MF	GO:0052689	carboxylic ester hydrolase activity	IEP	Predicted GO
MF	GO:0070006	metalloaminopeptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Predicted GO
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
MF	GO:0098518	polynucleotide phosphatase activity	IEP	Predicted GO
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1990481	mRNA pseudouridine synthesis	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012947	tRNA_SAD	955	1013
IPR018164	Ala-tRNA-synth_IIc_N	194	810

External Links

PlasmoDB	PB001101.00.0
PlasmoDB	PBANKA_114360

PBANKA_1143600 (AlaRS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation