PBANKA_1340000 (DHFS-FPGS)

Aliases : DHFS-FPGS

Description : SSF53244: Mur ligase, C-terminal domain superfamily, SSF53623: Mur-like, catalytic domain superfamily. Pfam domain(s): PF08245: Mur ligase middle domain.

Gene families : OG_01_0001896 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001896_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1340000
Cluster	P. berghei: Cluster_15

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006575	cellular modified amino acid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006732	coenzyme metabolic process	None	Extended
BP	GO:0006760	folic acid-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	IEA	Interproscan predictions
BP	GO:0009058	biosynthetic process	IEA	PlasmoDB
BP	GO:0009108	coenzyme biosynthetic process	None	Extended
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEA	PlasmoDB
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016874	ligase activity	IEA	PlasmoDB
MF	GO:0016879	ligase activity, forming carbon-nitrogen bonds	None	Extended
MF	GO:0016881	acid-amino acid ligase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042398	cellular modified amino acid biosynthetic process	None	Extended
BP	GO:0042558	pteridine-containing compound metabolic process	None	Extended
BP	GO:0042559	pteridine-containing compound biosynthetic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0043604	amide biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	Predicted GO
MF	GO:0003712	transcription coregulator activity	IEP	Predicted GO
MF	GO:0003713	transcription coactivator activity	IEP	Predicted GO
MF	GO:0004053	arginase activity	IEP	Predicted GO
MF	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004520	endodeoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004536	deoxyribonuclease activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004661	protein geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0004663	Rab geranylgeranyltransferase activity	IEP	Predicted GO
MF	GO:0004802	transketolase activity	IEP	Predicted GO
MF	GO:0005048	signal sequence binding	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005337	nucleoside transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005345	purine nucleobase transmembrane transporter activity	IEP	Predicted GO
MF	GO:0005371	tricarboxylate secondary active transmembrane transporter activity	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
CC	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	IEP	Predicted GO
CC	GO:0005768	endosome	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
CC	GO:0005956	protein kinase CK2 complex	IEP	Predicted GO
CC	GO:0005968	Rab-protein geranylgeranyltransferase complex	IEP	Predicted GO
BP	GO:0006289	nucleotide-excision repair	IEP	Predicted GO
BP	GO:0006457	protein folding	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006525	arginine metabolic process	IEP	Predicted GO
BP	GO:0006528	asparagine metabolic process	IEP	Predicted GO
BP	GO:0006529	asparagine biosynthetic process	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0006811	ion transport	IEP	Predicted GO
BP	GO:0006839	mitochondrial transport	IEP	Predicted GO
BP	GO:0006842	tricarboxylic acid transport	IEP	Predicted GO
BP	GO:0006843	mitochondrial citrate transmembrane transport	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0006863	purine nucleobase transport	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008318	protein prenyltransferase activity	IEP	Predicted GO
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009143	nucleoside triphosphate catabolic process	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015142	tricarboxylic acid transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015205	nucleobase transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015211	purine nucleoside transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015746	citrate transport	IEP	Predicted GO
BP	GO:0015851	nucleobase transport	IEP	Predicted GO
BP	GO:0015858	nucleoside transport	IEP	Predicted GO
BP	GO:0015860	purine nucleoside transmembrane transport	IEP	Predicted GO
BP	GO:0015893	drug transport	IEP	Predicted GO
BP	GO:0015931	nucleobase-containing compound transport	IEP	Predicted GO
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016744	transferase activity, transferring aldehyde or ketonic groups	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	IEP	Predicted GO
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Predicted GO
MF	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	IEP	Predicted GO
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Predicted GO
BP	GO:0018342	protein prenylation	IEP	Predicted GO
BP	GO:0018344	protein geranylgeranylation	IEP	Predicted GO
MF	GO:0019207	kinase regulator activity	IEP	Predicted GO
BP	GO:0019538	protein metabolic process	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
MF	GO:0019887	protein kinase regulator activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0022857	transmembrane transporter activity	IEP	Predicted GO
BP	GO:0030150	protein import into mitochondrial matrix	IEP	Predicted GO
MF	GO:0030943	mitochondrion targeting sequence binding	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
MF	GO:0032451	demethylase activity	IEP	Predicted GO
MF	GO:0033218	amide binding	IEP	Predicted GO
BP	GO:0035674	tricarboxylic acid transmembrane transport	IEP	Predicted GO
BP	GO:0042026	protein refolding	IEP	Predicted GO
MF	GO:0042277	peptide binding	IEP	Predicted GO
BP	GO:0042891	antibiotic transport	IEP	Predicted GO
CC	GO:0043186	P granule	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044238	primary metabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044444	cytoplasmic part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0044743	protein transmembrane import into intracellular organelle	IEP	Predicted GO
MF	GO:0047429	nucleoside-triphosphate diphosphatase activity	IEP	Predicted GO
MF	GO:0051082	unfolded protein binding	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0051920	peroxiredoxin activity	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070988	demethylation	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0072530	purine-containing compound transmembrane transport	IEP	Predicted GO
BP	GO:0097354	prenylation	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:0098656	anion transmembrane transport	IEP	Predicted GO
CC	GO:0098800	inner mitochondrial membrane protein complex	IEP	Predicted GO
BP	GO:1901264	carbohydrate derivative transport	IEP	Predicted GO
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Predicted GO
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Predicted GO
BP	GO:1901642	nucleoside transmembrane transport	IEP	Predicted GO
BP	GO:1903825	organic acid transmembrane transport	IEP	Predicted GO
BP	GO:1905039	carboxylic acid transmembrane transport	IEP	Predicted GO
BP	GO:1990542	mitochondrial transmembrane transport	IEP	Predicted GO
BP	GO:1990546	mitochondrial tricarboxylic acid transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013221	Mur_ligase_cen	47	218

External Links

PlasmoDB	PB000177.03.0
PlasmoDB	PBANKA_134000

PBANKA_1340000 (DHFS-FPGS)

Expression Profile

Co-expression Networks

Functional Annotation