PBANKA_1454000 (GyrB)

Aliases : GyrB

Description : SSF54211: Ribosomal protein S5 domain 2-type fold, SSF56719: DNA topoisomerase, type IIA-like domain superfamily, SSF55874: Histidine kinase/HSP90-like ATPase superfamily. Pfam domain(s): PF00986: DNA gyrase B subunit, carboxyl terminus, PF02518: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, PF01751: Toprim domain, PF00204: DNA gyrase B.

Gene families : OG_01_0002210 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0002210_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pbe RNA-seq: PBANKA_1454000
Cluster	P. berghei: Cluster_35

Target	Alias	Description	ECC score	Gene Family Method	Actions
PF3D7_1239500	GyrB	SSF56719: "DNA topoisomerase, type IIA-like domain...	0.01	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan predictions
MF	GO:0003677	DNA binding	IEA	PlasmoDB
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	Interproscan predictions
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan predictions
BP	GO:0006265	DNA topological change	IEA	PlasmoDB
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	DNA-dependent ATPase activity	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
CC	GO:0020011	apicoplast	ISO	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
MF	GO:0061505	DNA topoisomerase II activity	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000785	chromatin	IEP	Predicted GO
CC	GO:0000792	heterochromatin	IEP	Predicted GO
MF	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity	IEP	Predicted GO
MF	GO:0004305	ethanolamine kinase activity	IEP	Predicted GO
MF	GO:0004425	indole-3-glycerol-phosphate synthase activity	IEP	Predicted GO
MF	GO:0004831	tyrosine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005049	nuclear export signal receptor activity	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006437	tyrosyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008234	cysteine-type peptidase activity	IEP	Predicted GO
BP	GO:0008283	cell proliferation	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
BP	GO:0010033	response to organic substance	IEP	Predicted GO
BP	GO:0010243	response to organonitrogen compound	IEP	Predicted GO
BP	GO:0010498	proteasomal protein catabolic process	IEP	Predicted GO
BP	GO:0015074	DNA integration	IEP	Predicted GO
MF	GO:0016289	CoA hydrolase activity	IEP	Predicted GO
MF	GO:0016782	transferase activity, transferring sulfur-containing groups	IEP	Predicted GO
MF	GO:0016783	sulfurtransferase activity	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
CC	GO:0030117	membrane coat	IEP	Predicted GO
CC	GO:0030118	clathrin coat	IEP	Predicted GO
CC	GO:0030120	vesicle coat	IEP	Predicted GO
CC	GO:0030125	clathrin vesicle coat	IEP	Predicted GO
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	IEP	Predicted GO
CC	GO:0030132	clathrin coat of coated pit	IEP	Predicted GO
BP	GO:0030163	protein catabolic process	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
BP	GO:0030433	ubiquitin-dependent ERAD pathway	IEP	Predicted GO
MF	GO:0031071	cysteine desulfurase activity	IEP	Predicted GO
BP	GO:0031935	regulation of chromatin silencing	IEP	Predicted GO
MF	GO:0032051	clathrin light chain binding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034450	ubiquitin-ubiquitin ligase activity	IEP	Predicted GO
BP	GO:0034976	response to endoplasmic reticulum stress	IEP	Predicted GO
BP	GO:0036503	ERAD pathway	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
CC	GO:0044433	cytoplasmic vesicle part	IEP	Predicted GO
BP	GO:0048268	clathrin coat assembly	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0060968	regulation of gene silencing	IEP	Predicted GO
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Predicted GO
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Predicted GO
CC	GO:0071006	U2-type catalytic step 1 spliceosome	IEP	Predicted GO
CC	GO:0071012	catalytic step 1 spliceosome	IEP	Predicted GO
CC	GO:0071439	clathrin complex	IEP	Predicted GO
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Predicted GO
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO
BP	GO:1901698	response to nitrogen compound	IEP	Predicted GO
BP	GO:1902275	regulation of chromatin organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003594	HATPase_C	138	327
IPR002288	DNA_gyrase_B_C	854	914
IPR013506	Topo_IIA_bsu_dom2	399	571
IPR006171	TOPRIM_domain	601	733

External Links

PlasmoDB	PB000536.03.0
PlasmoDB	PBANKA_145400

PBANKA_1454000 (GyrB)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation