PF3D7_0623800 (TKL4)

Aliases : TKL4

Description : SSF56112: Protein kinase-like domain superfamily, SSF48371: Armadillo-type fold. Pfam domain(s): PF00069: Protein kinase domain.

Gene families : OG_01_0000153 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000153_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0623800
Cluster	P. falciparum: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1122700	TKL4	SSF56112: Protein kinase-like domain superfamily. Pfam...	0.06	Orthofinderv1.1.8
PBANKA_1228800	No alias	SSF56112: Protein kinase-like domain superfamily. Pfam...	0.07	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004672	protein kinase activity	ISS	PlasmoDB
MF	GO:0004672	protein kinase activity	IEA	Interproscan predictions
MF	GO:0004672	protein kinase activity	IEA	PlasmoDB
MF	GO:0005488	binding	None	Extended
MF	GO:0005488	binding	IEA	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006468	protein phosphorylation	ISS	PlasmoDB
BP	GO:0006468	protein phosphorylation	IEA	Interproscan predictions
BP	GO:0006468	protein phosphorylation	IEA	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016301	kinase activity	None	Extended
BP	GO:0016310	phosphorylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000118	histone deacetylase complex	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0000469	cleavage involved in rRNA processing	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004012	phospholipid-translocating ATPase activity	IEP	Predicted GO
MF	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity	IEP	Predicted GO
MF	GO:0004407	histone deacetylase activity	IEP	Predicted GO
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0005977	glycogen metabolic process	IEP	Predicted GO
BP	GO:0005978	glycogen biosynthetic process	IEP	Predicted GO
BP	GO:0006073	cellular glucan metabolic process	IEP	Predicted GO
BP	GO:0006112	energy reserve metabolic process	IEP	Predicted GO
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006900	vesicle budding from membrane	IEP	Predicted GO
MF	GO:0008878	glucose-1-phosphate adenylyltransferase activity	IEP	Predicted GO
BP	GO:0009250	glucan biosynthetic process	IEP	Predicted GO
BP	GO:0010452	histone H3-K36 methylation	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015917	aminophospholipid transport	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0016050	vesicle organization	IEP	Predicted GO
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
CC	GO:0020007	apical complex	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
BP	GO:0020027	hemoglobin metabolic process	IEP	Predicted GO
MF	GO:0022804	active transmembrane transporter activity	IEP	Predicted GO
CC	GO:0030015	CCR4-NOT core complex	IEP	Predicted GO
CC	GO:0030430	host cell cytoplasm	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
MF	GO:0033558	protein deacetylase activity	IEP	Predicted GO
CC	GO:0033643	host cell part	IEP	Predicted GO
CC	GO:0033646	host intracellular part	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
CC	GO:0034399	nuclear periphery	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0042000	translocation of peptides or proteins into host	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
BP	GO:0042540	hemoglobin catabolic process	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
CC	GO:0043190	ATP-binding cassette (ABC) transporter complex	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
BP	GO:0044042	glucan metabolic process	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0044417	translocation of molecules into host	IEP	Predicted GO
BP	GO:0044766	multi-organism transport	IEP	Predicted GO
MF	GO:0046975	histone methyltransferase activity (H3-K36 specific)	IEP	Predicted GO
BP	GO:0051252	regulation of RNA metabolic process	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051808	translocation of peptides or proteins into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051836	translocation of molecules into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0055088	lipid homeostasis	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
MF	GO:0070567	cytidylyltransferase activity	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
CC	GO:0098533	ATPase dependent transmembrane transport complex	IEP	Predicted GO
BP	GO:1902579	multi-organism localization	IEP	Predicted GO
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Predicted GO
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000719	Prot_kinase_dom	2171	2395

External Links

PlasmoDB	2270.t00551
PlasmoDB	3885874
PlasmoDB	MAL6P1.191
PlasmoDB	PFF1145c

PF3D7_0623800 (TKL4)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation