PF3D7_1116800 (HSP101)

Aliases : HSP101

Description : SSF81923: "Clp, N-terminal domain superfamily", SSF52540: P-loop containing nucleoside triphosphate hydrolase. Pfam domain(s): PF07724: AAA domain (Cdc48 subfamily), PF10431: "C-terminal, D2-small domain, of ClpB protein", PF00004: ATPase family associated with various cellular activities (AAA), PF02861: "Clp amino terminal domain, pathogenicity island component", PF17871: AAA lid domain.

Gene families : OG_01_0000034 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000034_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1116800
Cluster	P. falciparum: Cluster_39

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0931200	HSP101	SSF81923: Clp, N-terminal domain superfamily, SSF52540:...	0.11	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	PlasmoDB
MF	GO:0005524	ATP binding	IEA	Interproscan predictions
MF	GO:0005524	ATP binding	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006986	response to unfolded protein	ISS	PlasmoDB
BP	GO:0008104	protein localization	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009266	response to temperature stimulus	None	Extended
BP	GO:0009408	response to heat	ISS	PlasmoDB
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0010033	response to organic substance	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0019538	protein metabolic process	IEA	PlasmoDB
CC	GO:0020003	symbiont-containing vacuole	IDA	PlasmoDB
CC	GO:0020005	symbiont-containing vacuole membrane	IDA	PlasmoDB
CC	GO:0020007	apical complex	IDA	PlasmoDB
CC	GO:0020026	merozoite dense granule	IDA	PlasmoDB
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
BP	GO:0035966	response to topologically incorrect protein	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042000	translocation of peptides or proteins into host	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0042886	amide transport	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IMP	PlasmoDB
CC	GO:0044217	other organism part	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044417	translocation of molecules into host	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0044766	multi-organism transport	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051808	translocation of peptides or proteins into other organism involved in symbiotic interaction	None	Extended
BP	GO:0051836	translocation of molecules into other organism involved in symbiotic interaction	None	Extended
CC	GO:0065010	extracellular membrane-bounded organelle	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0097619	PTEX complex	IDA	PlasmoDB
CC	GO:0097708	intracellular vesicle	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1902579	multi-organism localization	None	Extended
CC	GO:1903561	extracellular vesicle	RCA	PlasmoDB

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Type	GO Term	Name	Evidence	Source
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
CC	GO:0000323	lytic vacuole	IEP	Predicted GO
BP	GO:0000469	cleavage involved in rRNA processing	IEP	Predicted GO
MF	GO:0004012	phospholipid-translocating ATPase activity	IEP	Predicted GO
MF	GO:0004301	epoxide hydrolase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
CC	GO:0005764	lysosome	IEP	Predicted GO
CC	GO:0005767	secondary lysosome	IEP	Predicted GO
CC	GO:0005773	vacuole	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0005977	glycogen metabolic process	IEP	Predicted GO
BP	GO:0005978	glycogen biosynthetic process	IEP	Predicted GO
BP	GO:0006073	cellular glucan metabolic process	IEP	Predicted GO
BP	GO:0006112	energy reserve metabolic process	IEP	Predicted GO
BP	GO:0006900	vesicle budding from membrane	IEP	Predicted GO
MF	GO:0008878	glucose-1-phosphate adenylyltransferase activity	IEP	Predicted GO
BP	GO:0009250	glucan biosynthetic process	IEP	Predicted GO
MF	GO:0009678	hydrogen-translocating pyrophosphatase activity	IEP	Predicted GO
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015917	aminophospholipid transport	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
BP	GO:0016050	vesicle organization	IEP	Predicted GO
MF	GO:0016801	hydrolase activity, acting on ether bonds	IEP	Predicted GO
MF	GO:0016803	ether hydrolase activity	IEP	Predicted GO
CC	GO:0020020	food vacuole	IEP	Predicted GO
CC	GO:0020036	Maurer's cleft	IEP	Predicted GO
CC	GO:0030139	endocytic vesicle	IEP	Predicted GO
MF	GO:0030507	spectrin binding	IEP	Predicted GO
CC	GO:0032010	phagolysosome	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
BP	GO:0043484	regulation of RNA splicing	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
BP	GO:0044042	glucan metabolic process	IEP	Predicted GO
CC	GO:0044164	host cell cytosol	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
CC	GO:0044228	host cell surface	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
CC	GO:0045335	phagocytic vesicle	IEP	Predicted GO
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050684	regulation of mRNA processing	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0055088	lipid homeostasis	IEP	Predicted GO
BP	GO:1902600	proton transmembrane transport	IEP	Predicted GO
BP	GO:1903311	regulation of mRNA metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003959	ATPase_AAA_core	232	351
IPR004176	Clp_N	51	96
IPR004176	Clp_N	125	170
IPR003959	ATPase_AAA_core	629	804
IPR019489	Clp_ATPase_C	810	886

External Links

PlasmoDB	810722
PlasmoDB	PF11_0175

PF3D7_1116800 (HSP101)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation