PF3D7_1136900 (SUB2)

Aliases : SUB2

Description : SSF52743: Peptidase S8/S53 domain superfamily. Pfam domain(s): PF18513: Prodomain subtilisin 2, PF00082: Subtilase family.

Gene families : OG_01_0001086 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001086_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1136900
Cluster	P. falciparum: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_0911700	SUB2	SSF52743: Peptidase S8/S53 domain superfamily. Pfam...	0.07	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004175	endopeptidase activity	None	Extended
MF	GO:0004252	serine-type endopeptidase activity	IEA	Interproscan predictions
MF	GO:0004252	serine-type endopeptidase activity	IEA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006508	proteolysis	IDA	PlasmoDB
BP	GO:0006508	proteolysis	IEA	Interproscan predictions
BP	GO:0006508	proteolysis	IEA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008236	serine-type peptidase activity	None	Extended
MF	GO:0008236	serine-type peptidase activity	IDA	PlasmoDB
CC	GO:0016021	integral component of membrane	IDA	PlasmoDB
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0017171	serine hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020009	microneme	IDA	PlasmoDB
CC	GO:0020026	merozoite dense granule	IDA	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0031410	cytoplasmic vesicle	None	Extended
CC	GO:0031982	vesicle	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
CC	GO:0044310	osmiophilic body	IDA	PlasmoDB
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0051604	protein maturation	IDA	PlasmoDB
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
CC	GO:0097708	intracellular vesicle	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000910	cytokinesis	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	IEP	Predicted GO
MF	GO:0004354	glutamate dehydrogenase (NADP+) activity	IEP	Predicted GO
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Predicted GO
MF	GO:0004568	chitinase activity	IEP	Predicted GO
MF	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity	IEP	Predicted GO
MF	GO:0004683	calmodulin-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004789	thiamine-phosphate diphosphorylase activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
MF	GO:0005539	glycosaminoglycan binding	IEP	Predicted GO
CC	GO:0005829	cytosol	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006026	aminoglycan catabolic process	IEP	Predicted GO
BP	GO:0006030	chitin metabolic process	IEP	Predicted GO
BP	GO:0006032	chitin catabolic process	IEP	Predicted GO
BP	GO:0006470	protein dephosphorylation	IEP	Predicted GO
MF	GO:0008061	chitin binding	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008201	heparin binding	IEP	Predicted GO
MF	GO:0008525	phosphatidylcholine transporter activity	IEP	Predicted GO
MF	GO:0008526	phosphatidylinositol transporter activity	IEP	Predicted GO
BP	GO:0009228	thiamine biosynthetic process	IEP	Predicted GO
BP	GO:0009405	pathogenesis	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
BP	GO:0016311	dephosphorylation	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
CC	GO:0020039	pellicle	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
CC	GO:0031225	anchored component of membrane	IEP	Predicted GO
CC	GO:0031244	extrinsic component of cell outer membrane	IEP	Predicted GO
BP	GO:0032368	regulation of lipid transport	IEP	Predicted GO
BP	GO:0032369	negative regulation of lipid transport	IEP	Predicted GO
MF	GO:0033691	sialic acid binding	IEP	Predicted GO
CC	GO:0035097	histone methyltransferase complex	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0035891	exit from host cell	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
BP	GO:0042724	thiamine-containing compound biosynthetic process	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
BP	GO:0043271	negative regulation of ion transport	IEP	Predicted GO
BP	GO:0044070	regulation of anion transport	IEP	Predicted GO
CC	GO:0044311	exoneme	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
BP	GO:0044419	interspecies interaction between organisms	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044462	external encapsulating structure part	IEP	Predicted GO
BP	GO:0044501	modulation of signal transduction in other organism	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0046348	amino sugar catabolic process	IEP	Predicted GO
MF	GO:0046789	host cell surface receptor binding	IEP	Predicted GO
MF	GO:0046812	host cell surface binding	IEP	Predicted GO
BP	GO:0048870	cell motility	IEP	Predicted GO
MF	GO:0051015	actin filament binding	IEP	Predicted GO
BP	GO:0051051	negative regulation of transport	IEP	Predicted GO
BP	GO:0051568	histone H3-K4 methylation	IEP	Predicted GO
BP	GO:0051701	interaction with host	IEP	Predicted GO
BP	GO:0051704	multi-organism process	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052027	modulation by symbiont of host signal transduction pathway	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052250	modulation of signal transduction in other organism involved in symbiotic interaction	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
BP	GO:0075109	modulation by symbiont of host receptor-mediated signal transduction	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
BP	GO:1901071	glucosamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901072	glucosamine-containing compound catabolic process	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO
BP	GO:1903792	negative regulation of anion transport	IEP	Predicted GO
BP	GO:1905952	regulation of lipid localization	IEP	Predicted GO
BP	GO:1905953	negative regulation of lipid localization	IEP	Predicted GO
BP	GO:2001138	regulation of phospholipid transport	IEP	Predicted GO
BP	GO:2001139	negative regulation of phospholipid transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000209	Peptidase_S8/S53_dom	746	997

External Links

PlasmoDB	810927
PlasmoDB	PF11_0381

PF3D7_1136900 (SUB2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation