PF3D7_1416500 (GDH1)

Aliases : GDH1

Description : SSF51735: NAD(P)-binding domain superfamily, SSF53223: No description available. Pfam domain(s): PF00208: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase, PF02812: "Glu/Leu/Phe/Val dehydrogenase, dimerisation domain".

Gene families : OG_01_0000138 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000138_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1416500
Cluster	P. falciparum: Cluster_12

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004353	glutamate dehydrogenase [NAD(P)+] activity	None	Extended
MF	GO:0004354	glutamate dehydrogenase (NADP+) activity	IDA	PlasmoDB
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005829	cytosol	IDA	PlasmoDB
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	IEA	Interproscan predictions
BP	GO:0006520	cellular amino acid metabolic process	IEA	PlasmoDB
BP	GO:0006536	glutamate metabolic process	IDA	PlasmoDB
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009064	glutamine family amino acid metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016491	oxidoreductase activity	IEA	Interproscan predictions
MF	GO:0016491	oxidoreductase activity	IEA	PlasmoDB
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	None	Extended
MF	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	IEA	PlasmoDB
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0043648	dicarboxylic acid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0055114	oxidation-reduction process	IEA	Interproscan predictions
BP	GO:0055114	oxidation-reduction process	IEA	PlasmoDB
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain	IEP	Predicted GO
BP	GO:0000910	cytokinesis	IEP	Predicted GO
MF	GO:0004108	citrate (Si)-synthase activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004307	ethanolaminephosphotransferase activity	IEP	Predicted GO
MF	GO:0004467	long-chain fatty acid-CoA ligase activity	IEP	Predicted GO
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEP	Predicted GO
MF	GO:0004568	chitinase activity	IEP	Predicted GO
BP	GO:0006022	aminoglycan metabolic process	IEP	Predicted GO
BP	GO:0006026	aminoglycan catabolic process	IEP	Predicted GO
BP	GO:0006030	chitin metabolic process	IEP	Predicted GO
BP	GO:0006032	chitin catabolic process	IEP	Predicted GO
BP	GO:0006195	purine nucleotide catabolic process	IEP	Predicted GO
BP	GO:0006629	lipid metabolic process	IEP	Predicted GO
BP	GO:0006631	fatty acid metabolic process	IEP	Predicted GO
BP	GO:0006869	lipid transport	IEP	Predicted GO
MF	GO:0008061	chitin binding	IEP	Predicted GO
MF	GO:0008525	phosphatidylcholine transporter activity	IEP	Predicted GO
MF	GO:0008526	phosphatidylinositol transporter activity	IEP	Predicted GO
BP	GO:0009109	coenzyme catabolic process	IEP	Predicted GO
BP	GO:0009154	purine ribonucleotide catabolic process	IEP	Predicted GO
BP	GO:0009261	ribonucleotide catabolic process	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0015645	fatty acid ligase activity	IEP	Predicted GO
BP	GO:0015711	organic anion transport	IEP	Predicted GO
BP	GO:0015908	fatty acid transport	IEP	Predicted GO
BP	GO:0015909	long-chain fatty acid transport	IEP	Predicted GO
MF	GO:0016405	CoA-ligase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0016878	acid-thiol ligase activity	IEP	Predicted GO
MF	GO:0017169	CDP-alcohol phosphatidyltransferase activity	IEP	Predicted GO
BP	GO:0019368	fatty acid elongation, unsaturated fatty acid	IEP	Predicted GO
CC	GO:0020005	symbiont-containing vacuole membrane	IEP	Predicted GO
CC	GO:0020009	microneme	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
CC	GO:0020039	pellicle	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
BP	GO:0030497	fatty acid elongation	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0032368	regulation of lipid transport	IEP	Predicted GO
BP	GO:0032369	negative regulation of lipid transport	IEP	Predicted GO
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Predicted GO
BP	GO:0033869	nucleoside bisphosphate catabolic process	IEP	Predicted GO
BP	GO:0034031	ribonucleoside bisphosphate catabolic process	IEP	Predicted GO
BP	GO:0034034	purine nucleoside bisphosphate catabolic process	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0035891	exit from host cell	IEP	Predicted GO
MF	GO:0036440	citrate synthase activity	IEP	Predicted GO
BP	GO:0040011	locomotion	IEP	Predicted GO
BP	GO:0042777	plasma membrane ATP synthesis coupled proton transport	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
BP	GO:0043271	negative regulation of ion transport	IEP	Predicted GO
CC	GO:0043657	host cell	IEP	Predicted GO
BP	GO:0044070	regulation of anion transport	IEP	Predicted GO
CC	GO:0044216	other organism cell	IEP	Predicted GO
CC	GO:0044217	other organism part	IEP	Predicted GO
CC	GO:0044228	host cell surface	IEP	Predicted GO
BP	GO:0044255	cellular lipid metabolic process	IEP	Predicted GO
BP	GO:0044273	sulfur compound catabolic process	IEP	Predicted GO
CC	GO:0044311	exoneme	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
BP	GO:0044419	interspecies interaction between organisms	IEP	Predicted GO
CC	GO:0044421	extracellular region part	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0046348	amino sugar catabolic process	IEP	Predicted GO
BP	GO:0046356	acetyl-CoA catabolic process	IEP	Predicted GO
MF	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	IEP	Predicted GO
BP	GO:0048870	cell motility	IEP	Predicted GO
BP	GO:0051051	negative regulation of transport	IEP	Predicted GO
BP	GO:0051187	cofactor catabolic process	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051701	interaction with host	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
BP	GO:1901071	glucosamine-containing compound metabolic process	IEP	Predicted GO
BP	GO:1901072	glucosamine-containing compound catabolic process	IEP	Predicted GO
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Predicted GO
BP	GO:1903792	negative regulation of anion transport	IEP	Predicted GO
BP	GO:1905952	regulation of lipid localization	IEP	Predicted GO
BP	GO:1905953	negative regulation of lipid localization	IEP	Predicted GO
BP	GO:2001138	regulation of phospholipid transport	IEP	Predicted GO
BP	GO:2001139	negative regulation of phospholipid transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006097	Glu/Leu/Phe/Val_DH_dimer_dom	77	205
IPR006096	Glu/Leu/Phe/Val_DH_C	222	468

External Links

PlasmoDB	811745
PlasmoDB	PF14_0164

PF3D7_1416500 (GDH1)

Expression Profile

Co-expression Networks

Functional Annotation