PF3D7_0102500 (EBA181)

Aliases : EBA181

Description : SSF140924: No description available. Pfam domain(s): PF11556: Erythrocyte binding antigen 175, PF05424: Duffy binding domain.

Gene families : OG_01_0000012 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000012_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0102500
Cluster	P. falciparum: Cluster_12

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005539	glycosaminoglycan binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0008201	heparin binding	IDA	PlasmoDB
BP	GO:0009405	pathogenesis	IEA	Interproscan predictions
BP	GO:0009405	pathogenesis	IEA	PlasmoDB
CC	GO:0016021	integral component of membrane	IEA	Interproscan predictions
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
CC	GO:0020009	microneme	IDA	PlasmoDB
BP	GO:0030260	entry into host cell	IDA	PlasmoDB
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0031406	carboxylic acid binding	None	Extended
CC	GO:0031982	vesicle	None	Extended
MF	GO:0033691	sialic acid binding	IDA	PlasmoDB
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043177	organic acid binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044409	entry into host	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044425	membrane part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046789	host cell surface receptor binding	IEA	Interproscan predictions
MF	GO:0046789	host cell surface receptor binding	IEA	PlasmoDB
MF	GO:0046812	host cell surface binding	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051828	entry into other organism involved in symbiotic interaction	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901681	sulfur compound binding	None	Extended
CC	GO:1903561	extracellular vesicle	IDA	PlasmoDB

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Type	GO Term	Name	Evidence	Source
MF	GO:0001791	IgM binding	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004683	calmodulin-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008525	phosphatidylcholine transporter activity	IEP	Predicted GO
MF	GO:0008526	phosphatidylinositol transporter activity	IEP	Predicted GO
CC	GO:0009986	cell surface	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019865	immunoglobulin binding	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
CC	GO:0020008	rhoptry	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
BP	GO:0032368	regulation of lipid transport	IEP	Predicted GO
BP	GO:0032369	negative regulation of lipid transport	IEP	Predicted GO
BP	GO:0032879	regulation of localization	IEP	Predicted GO
BP	GO:0035890	exit from host	IEP	Predicted GO
BP	GO:0035891	exit from host cell	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
BP	GO:0043271	negative regulation of ion transport	IEP	Predicted GO
BP	GO:0044070	regulation of anion transport	IEP	Predicted GO
BP	GO:0044501	modulation of signal transduction in other organism	IEP	Predicted GO
CC	GO:0045177	apical part of cell	IEP	Predicted GO
BP	GO:0051049	regulation of transport	IEP	Predicted GO
BP	GO:0051051	negative regulation of transport	IEP	Predicted GO
BP	GO:0052027	modulation by symbiont of host signal transduction pathway	IEP	Predicted GO
BP	GO:0052126	movement in host environment	IEP	Predicted GO
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052250	modulation of signal transduction in other organism involved in symbiotic interaction	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
CC	GO:0070258	inner membrane pellicle complex	IEP	Predicted GO
BP	GO:0075109	modulation by symbiont of host receptor-mediated signal transduction	IEP	Predicted GO
BP	GO:1903792	negative regulation of anion transport	IEP	Predicted GO
BP	GO:1905952	regulation of lipid localization	IEP	Predicted GO
BP	GO:1905953	negative regulation of lipid localization	IEP	Predicted GO
CC	GO:1990225	rhoptry neck	IEP	Predicted GO
BP	GO:2001138	regulation of phospholipid transport	IEP	Predicted GO
BP	GO:2001139	negative regulation of phospholipid transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR021620	EBA-175_C	1402	1481
IPR008602	Duffy-antigen_binding	456	616
IPR008602	Duffy-antigen_binding	148	269

External Links

PlasmoDB	MAL1P1.16
PlasmoDB	PFA0125c

PF3D7_0102500 (EBA181)

Expression Profile

Co-expression Networks

Functional Annotation