PF3D7_1464600 (UIS2)

Aliases : UIS2

Description : SSF56300: No description available. Pfam domain(s): PF00149: Calcineurin-like phosphoesterase.

Gene families : OG_01_0001845 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0001845_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_1464600
Cluster	P. falciparum: Cluster_12

Target	Alias	Description	ECC score	Gene Family Method	Actions
PBANKA_1328000	UIS2	SSF56300: 20-02-2019. Pfam domain(s): PF00149:...	0.11	Orthofinderv1.1.8

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006470	protein dephosphorylation	ISO	PlasmoDB
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016311	dephosphorylation	None	Extended
MF	GO:0016787	hydrolase activity	IEA	Interproscan predictions
MF	GO:0016787	hydrolase activity	IEA	PlasmoDB
BP	GO:0019538	protein metabolic process	None	Extended
CC	GO:0020003	symbiont-containing vacuole	IDA	PlasmoDB
CC	GO:0020005	symbiont-containing vacuole membrane	ISO	PlasmoDB
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043230	extracellular organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
CC	GO:0044217	other organism part	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044421	extracellular region part	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0065010	extracellular membrane-bounded organelle	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	IEP	Predicted GO
CC	GO:0000109	nucleotide-excision repair complex	IEP	Predicted GO
CC	GO:0000112	nucleotide-excision repair factor 3 complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000469	cleavage involved in rRNA processing	IEP	Predicted GO
BP	GO:0002028	regulation of sodium ion transport	IEP	Predicted GO
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Predicted GO
MF	GO:0004012	phospholipid-translocating ATPase activity	IEP	Predicted GO
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity	IEP	Predicted GO
MF	GO:0005215	transporter activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
MF	GO:0005539	glycosaminoglycan binding	IEP	Predicted GO
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	IEP	Predicted GO
BP	GO:0006810	transport	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008201	heparin binding	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
BP	GO:0009405	pathogenesis	IEP	Predicted GO
BP	GO:0010959	regulation of metal ion transport	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0015917	aminophospholipid transport	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
CC	GO:0020007	apical complex	IEP	Predicted GO
CC	GO:0020009	microneme	IEP	Predicted GO
CC	GO:0020026	merozoite dense granule	IEP	Predicted GO
CC	GO:0030015	CCR4-NOT core complex	IEP	Predicted GO
BP	GO:0030260	entry into host cell	IEP	Predicted GO
BP	GO:0031204	posttranslational protein targeting to membrane, translocation	IEP	Predicted GO
CC	GO:0031207	Sec62/Sec63 complex	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
CC	GO:0031410	cytoplasmic vesicle	IEP	Predicted GO
CC	GO:0031982	vesicle	IEP	Predicted GO
BP	GO:0032879	regulation of localization	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
BP	GO:0033683	nucleotide-excision repair, DNA incision	IEP	Predicted GO
MF	GO:0033691	sialic acid binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
BP	GO:0042000	translocation of peptides or proteins into host	IEP	Predicted GO
BP	GO:0042221	response to chemical	IEP	Predicted GO
BP	GO:0042493	response to drug	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043269	regulation of ion transport	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
BP	GO:0044053	translocation of peptides or proteins into host cell cytoplasm	IEP	Predicted GO
BP	GO:0044409	entry into host	IEP	Predicted GO
BP	GO:0044417	translocation of molecules into host	IEP	Predicted GO
BP	GO:0044419	interspecies interaction between organisms	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
BP	GO:0044501	modulation of signal transduction in other organism	IEP	Predicted GO
BP	GO:0044766	multi-organism transport	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
MF	GO:0046789	host cell surface receptor binding	IEP	Predicted GO
MF	GO:0046812	host cell surface binding	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051049	regulation of transport	IEP	Predicted GO
BP	GO:0051179	localization	IEP	Predicted GO
BP	GO:0051234	establishment of localization	IEP	Predicted GO
BP	GO:0051260	protein homooligomerization	IEP	Predicted GO
BP	GO:0051701	interaction with host	IEP	Predicted GO
BP	GO:0051704	multi-organism process	IEP	Predicted GO
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051808	translocation of peptides or proteins into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051828	entry into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0051836	translocation of molecules into other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0052027	modulation by symbiont of host signal transduction pathway	IEP	Predicted GO
BP	GO:0052250	modulation of signal transduction in other organism involved in symbiotic interaction	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0055088	lipid homeostasis	IEP	Predicted GO
MF	GO:0061505	DNA topoisomerase II activity	IEP	Predicted GO
MF	GO:0070567	cytidylyltransferase activity	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0071705	nitrogen compound transport	IEP	Predicted GO
BP	GO:0075109	modulation by symbiont of host receptor-mediated signal transduction	IEP	Predicted GO
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
CC	GO:0097619	PTEX complex	IEP	Predicted GO
CC	GO:0097708	intracellular vesicle	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901681	sulfur compound binding	IEP	Predicted GO
BP	GO:1902579	multi-organism localization	IEP	Predicted GO
CC	GO:1903561	extracellular vesicle	IEP	Predicted GO
CC	GO:1990391	DNA repair complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004843	Calcineurin-like_PHP_ApaH	764	941

External Links

PlasmoDB	812196
PlasmoDB	PF14_0614

PF3D7_1464600 (UIS2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation