PF3D7_0420900 (VAR)


Aliases : VAR

Description : SSF140924: No description available. Pfam domain(s): PF15447: N-terminal segments of PfEMP1, PF05424: Duffy binding domain, PF18562: Cysteine-Rich Interdomain Region 1 gamma, PF15445: "acidic terminal segments, variant surface antigen of PfEMP1", PF03011: PFEMP DBL domain.


Gene families : OG_01_0000012 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000012_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Pfa RNA-seq: PF3D7_0420900
Cluster P. falciparum: Cluster_13

Target Alias Description ECC score Gene Family Method Actions
PF3D7_0421300 VAR SSF140924: No description available. Pfam domain(s):... 0.04 Orthofinderv1.1.8

Type GO Term Name Evidence Source
BP GO:0009405 pathogenesis IEA Interproscan predictions
BP GO:0009405 pathogenesis IEA PlasmoDB
CC GO:0016021 integral component of membrane IEA Interproscan predictions
CC GO:0016021 integral component of membrane IEA PlasmoDB
CC GO:0020002 host cell plasma membrane TAS PlasmoDB
BP GO:0020013 modulation by symbiont of host erythrocyte aggregation TAS PlasmoDB
CC GO:0020030 infected host cell surface knob TAS PlasmoDB
BP GO:0020033 antigenic variation TAS PlasmoDB
BP GO:0020035 cytoadherence to microvasculature, mediated by symbiont protein TAS PlasmoDB
MF GO:0046789 host cell surface receptor binding IEA Interproscan predictions
MF GO:0046789 host cell surface receptor binding IEA PlasmoDB
MF GO:0050839 cell adhesion molecule binding TAS PlasmoDB
Type GO Term Name Evidence Source
BP GO:0009106 lipoate metabolic process IEP Predicted GO
BP GO:0009107 lipoate biosynthetic process IEP Predicted GO
BP GO:0009249 protein lipoylation IEP Predicted GO
MF GO:0016979 lipoate-protein ligase activity IEP Predicted GO
BP GO:0018065 protein-cofactor linkage IEP Predicted GO
CC GO:0020003 symbiont-containing vacuole IEP Predicted GO
CC GO:0020036 Maurer's cleft IEP Predicted GO
MF GO:0033819 lipoyl(octanoyl) transferase activity IEP Predicted GO
CC GO:0043230 extracellular organelle IEP Predicted GO
CC GO:0044421 extracellular region part IEP Predicted GO
CC GO:0065010 extracellular membrane-bounded organelle IEP Predicted GO
InterPro domains Description Start Stop
IPR029211 PfEMP1_ATS 1763 2201
IPR004258 DBL 656 805
IPR004258 DBL 1475 1621
IPR029210 PfEMP1_NTS 20 55
IPR008602 Duffy-antigen_binding 126 279
IPR008602 Duffy-antigen_binding 934 1123
PlasmoDB 4794161
PlasmoDB MAL4P1.195
PlasmoDB PFD1000c