PF3D7_0937800 (VAR)

Aliases : VAR

Description : SSF140924: No description available. Pfam domain(s): PF15447: N-terminal segments of PfEMP1, PF18562: Cysteine-Rich Interdomain Region 1 gamma, PF03011: PFEMP DBL domain, PF05424: Duffy binding domain, PF15445: "acidic terminal segments, variant surface antigen of PfEMP1".

Gene families : OG_01_0000012 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000012_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Pfa RNA-seq: PF3D7_0937800
Cluster	P. falciparum: Cluster_37

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009405	pathogenesis	IEA	Interproscan predictions
BP	GO:0009405	pathogenesis	IEA	PlasmoDB
BP	GO:0009605	response to external stimulus	None	Extended
BP	GO:0009607	response to biotic stimulus	None	Extended
CC	GO:0016021	integral component of membrane	IEA	Interproscan predictions
CC	GO:0016021	integral component of membrane	IEA	PlasmoDB
CC	GO:0020002	host cell plasma membrane	TAS	PlasmoDB
BP	GO:0020013	modulation by symbiont of host erythrocyte aggregation	TAS	PlasmoDB
CC	GO:0020030	infected host cell surface knob	TAS	PlasmoDB
BP	GO:0020033	antigenic variation	TAS	PlasmoDB
BP	GO:0020035	cytoadherence to microvasculature, mediated by symbiont protein	TAS	PlasmoDB
BP	GO:0022407	regulation of cell-cell adhesion	None	Extended
BP	GO:0022610	biological adhesion	None	Extended
BP	GO:0030155	regulation of cell adhesion	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
CC	GO:0033643	host cell part	None	Extended
CC	GO:0033644	host cell membrane	None	Extended
CC	GO:0033646	host intracellular part	None	Extended
CC	GO:0033655	host cell cytoplasm part	None	Extended
BP	GO:0034110	regulation of homotypic cell-cell adhesion	None	Extended
BP	GO:0034118	regulation of erythrocyte aggregation	None	Extended
BP	GO:0035821	modification of morphology or physiology of other organism	None	Extended
BP	GO:0043207	response to external biotic stimulus	None	Extended
BP	GO:0044003	modification by symbiont of host morphology or physiology	None	Extended
BP	GO:0044068	modulation by symbiont of host cellular process	None	Extended
CC	GO:0044217	other organism part	None	Extended
CC	GO:0044218	other organism cell membrane	None	Extended
CC	GO:0044279	other organism membrane	None	Extended
BP	GO:0044406	adhesion of symbiont to host	None	Extended
BP	GO:0044419	interspecies interaction between organisms	None	Extended
CC	GO:0044425	membrane part	None	Extended
MF	GO:0046789	host cell surface receptor binding	IEA	Interproscan predictions
MF	GO:0046789	host cell surface receptor binding	IEA	PlasmoDB
MF	GO:0046812	host cell surface binding	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
MF	GO:0050839	cell adhesion molecule binding	TAS	PlasmoDB
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051701	interaction with host	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051707	response to other organism	None	Extended
BP	GO:0051805	evasion or tolerance of immune response of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051807	evasion or tolerance of defense response of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051809	passive evasion of immune response of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051832	avoidance of defenses of other organism involved in symbiotic interaction	None	Extended
BP	GO:0051834	evasion or tolerance of defenses of other organism involved in symbiotic interaction	None	Extended
BP	GO:0052173	response to defenses of other organism involved in symbiotic interaction	None	Extended
BP	GO:0052564	response to immune response of other organism involved in symbiotic interaction	None	Extended
BP	GO:0065007	biological regulation	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
CC	GO:0000781	chromosome, telomeric region	IEP	Predicted GO
MF	GO:0003826	alpha-ketoacid dehydrogenase activity	IEP	Predicted GO
MF	GO:0004129	cytochrome-c oxidase activity	IEP	Predicted GO
MF	GO:0004690	cyclic nucleotide-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0004692	cGMP-dependent protein kinase activity	IEP	Predicted GO
MF	GO:0005200	structural constituent of cytoskeleton	IEP	Predicted GO
MF	GO:0005326	neurotransmitter transporter activity	IEP	Predicted GO
MF	GO:0005328	neurotransmitter:sodium symporter activity	IEP	Predicted GO
CC	GO:0005813	centrosome	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
CC	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex	IEP	Predicted GO
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predicted GO
BP	GO:0006091	generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0006655	phosphatidylglycerol biosynthetic process	IEP	Predicted GO
BP	GO:0006836	neurotransmitter transport	IEP	Predicted GO
MF	GO:0008324	cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	IEP	Predicted GO
MF	GO:0009055	electron transfer activity	IEP	Predicted GO
BP	GO:0009060	aerobic respiration	IEP	Predicted GO
MF	GO:0015002	heme-copper terminal oxidase activity	IEP	Predicted GO
MF	GO:0015075	ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015081	sodium ion transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015293	symporter activity	IEP	Predicted GO
MF	GO:0015294	solute:cation symporter activity	IEP	Predicted GO
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015370	solute:sodium symporter activity	IEP	Predicted GO
CC	GO:0015629	actin cytoskeleton	IEP	Predicted GO
BP	GO:0015980	energy derivation by oxidation of organic compounds	IEP	Predicted GO
MF	GO:0016409	palmitoyltransferase activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	IEP	Predicted GO
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	IEP	Predicted GO
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
MF	GO:0017169	CDP-alcohol phosphatidyltransferase activity	IEP	Predicted GO
BP	GO:0018345	protein palmitoylation	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
MF	GO:0022890	inorganic cation transmembrane transporter activity	IEP	Predicted GO
BP	GO:0022900	electron transport chain	IEP	Predicted GO
BP	GO:0022904	respiratory electron transport chain	IEP	Predicted GO
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
MF	GO:0042162	telomeric DNA binding	IEP	Predicted GO
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	IEP	Predicted GO
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	IEP	Predicted GO
BP	GO:0045333	cellular respiration	IEP	Predicted GO
BP	GO:0046471	phosphatidylglycerol metabolic process	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO
CC	GO:0098687	chromosomal region	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR029211	PfEMP1_ATS	1778	2264
IPR004258	DBL	642	808
IPR004258	DBL	1509	1652
IPR008602	Duffy-antigen_binding	960	1184
IPR008602	Duffy-antigen_binding	124	286
IPR029210	PfEMP1_NTS	17	54

External Links

PlasmoDB	813645
PlasmoDB	PFI1830c

PF3D7_0937800 (VAR)

Expression Profile

Co-expression Networks

Functional Annotation