Aliases : VAR
Description : SSF140924: No description available. Pfam domain(s): PF15447: N-terminal segments of PfEMP1, PF05424: Duffy binding domain, PF03011: PFEMP DBL domain, PF15445: "acidic terminal segments, variant surface antigen of PfEMP1".
Gene families : OG_01_0000012 (Orthofinderv1.1.8) Phylogenetic Tree(s): OG0000012_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Pfa RNA-seq: PF3D7_1200400 | No neighbors in network |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0000166 | nucleotide binding | IEA | PlasmoDB |
MF | GO:0003676 | nucleic acid binding | IEA | PlasmoDB |
MF | GO:0003887 | DNA-directed DNA polymerase activity | IEA | PlasmoDB |
BP | GO:0009405 | pathogenesis | IEA | Interproscan predictions |
BP | GO:0009405 | pathogenesis | IEA | PlasmoDB |
CC | GO:0016021 | integral component of membrane | IEA | Interproscan predictions |
CC | GO:0016021 | integral component of membrane | IEA | PlasmoDB |
CC | GO:0020002 | host cell plasma membrane | TAS | PlasmoDB |
BP | GO:0020013 | modulation by symbiont of host erythrocyte aggregation | TAS | PlasmoDB |
CC | GO:0020030 | infected host cell surface knob | TAS | PlasmoDB |
BP | GO:0020033 | antigenic variation | TAS | PlasmoDB |
BP | GO:0020035 | cytoadherence to microvasculature, mediated by symbiont protein | TAS | PlasmoDB |
MF | GO:0046789 | host cell surface receptor binding | TAS | PlasmoDB |
MF | GO:0046789 | host cell surface receptor binding | IEA | Interproscan predictions |
MF | GO:0046789 | host cell surface receptor binding | IEA | PlasmoDB |
MF | GO:0050839 | cell adhesion molecule binding | TAS | PlasmoDB |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR029211 | PfEMP1_ATS | 2438 | 2860 |
IPR029210 | PfEMP1_NTS | 25 | 61 |
IPR008602 | Duffy-antigen_binding | 1732 | 1876 |
IPR008602 | Duffy-antigen_binding | 862 | 1011 |
IPR008602 | Duffy-antigen_binding | 2114 | 2259 |
IPR008602 | Duffy-antigen_binding | 123 | 272 |
IPR008602 | Duffy-antigen_binding | 1284 | 1472 |
IPR004258 | DBL | 582 | 725 |
PlasmoDB | 2277.t00004 |
PlasmoDB | 811062 |
PlasmoDB | MAL12P1.4 |
PlasmoDB | PFL0020w |